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SMARCE1 SMARCE1 GAPDH GAPDH KCNAB2 KCNAB2 SDHA SDHA BMS1 BMS1 UBE2E1 UBE2E1 VDR VDR ANAPC4 ANAPC4 VDAC1 VDAC1 HDAC2 HDAC2 LOC106503207 LOC106503207 CDC23 CDC23 DPH6 DPH6 WDR36 WDR36 ATP5F1D ATP5F1D GTPBP4 GTPBP4 BAZ1B BAZ1B HDAC1 HDAC1 TRPC1 TRPC1 VDAC3 VDAC3 SPARC SPARC TOP2B TOP2B FBXO4 FBXO4 ATP5PF ATP5PF NEDD4 NEDD4 UBE2D1 UBE2D1 DKC1 DKC1 RIOK2 RIOK2 UQCRC2 UQCRC2 WDR75 WDR75 ACE2 ACE2 SMARCD1 SMARCD1 NPTX2 NPTX2 PXDN PXDN TRAF6 TRAF6 LSG1 LSG1 GNL2 GNL2 ATP6V1G1 ATP6V1G1 SMARCA4 SMARCA4 UQCRFS1 UQCRFS1 UQCRC1 UQCRC1 KRT14 KRT14 ATP5F1A ATP5F1A FBXO2 FBXO2 SDHB SDHB ATP5PB ATP5PB ACE ACE SUPT16H SUPT16H NOP10 NOP10 NCOA2 NCOA2 ATP5F1B ATP5F1B UBE2E3 UBE2E3 LOC108638252 LOC108638252 TCOF1 TCOF1 SMARCC1 SMARCC1 VSNL1 VSNL1 UBE2G2 UBE2G2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SMARCE1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1. (411 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase. (333 aa)
KCNAB2Potassium voltage-gated channel subfamily A regulatory beta subunit 2. (367 aa)
SDHASuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (665 aa)
BMS1BMS1 ribosome biogenesis factor. (1285 aa)
UBE2E1Ubiquitin conjugating enzyme E2 E1; Belongs to the ubiquitin-conjugating enzyme family. (202 aa)
VDRVitamin D receptor. (491 aa)
ANAPC4Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (805 aa)
VDAC1Voltage dependent anion channel 1. (283 aa)
HDAC2Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (488 aa)
LOC106503207Angiotensin-converting enzyme. (722 aa)
CDC23Cell division cycle 23. (597 aa)
DPH6Diphthine--ammonia ligase; Amidase that catalyzes the last step of diphthamide biosynthesis using ammonium and ATP. (267 aa)
WDR36WD repeat domain 36. (895 aa)
ATP5F1DATP synthase F1 subunit delta. (168 aa)
GTPBP4Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily. (634 aa)
BAZ1BBromodomain adjacent to zinc finger domain 1B. (1482 aa)
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (464 aa)
TRPC1Transient receptor potential cation channel subfamily C member 1; Belongs to the transient receptor (TC 1.A.4) family. (794 aa)
VDAC3Uncharacterized protein. (283 aa)
SPARCOsteonectin. (303 aa)
TOP2BDNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1609 aa)
FBXO4F-box protein 4. (393 aa)
ATP5PFATP synthase-coupling factor 6, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain; Belongs to the eukaryotic ATPase subunit F6 family. (108 aa)
NEDD4E3 ubiquitin-protein ligase. (836 aa)
UBE2D1UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
DKC1Dyskerin pseudouridine synthase 1. (506 aa)
RIOK2RIO kinase 2. (548 aa)
UQCRC2Ubiquinol-cytochrome c reductase core protein 2; Belongs to the peptidase M16 family. (453 aa)
WDR75WD repeat domain 75. (831 aa)
ACE2Angiotensin-converting enzyme. (804 aa)
SMARCD1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1. (515 aa)
NPTX2Neuronal pentraxin 2. (431 aa)
PXDNPeroxidasin. (1525 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (573 aa)
LSG1Large 60S subunit nuclear export GTPase 1. (653 aa)
GNL2Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily. (731 aa)
ATP6V1G1V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (118 aa)
SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4. (1606 aa)
UQCRFS1Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (274 aa)
UQCRC1Ubiquinol-cytochrome c reductase core protein 1. (480 aa)
KRT14Keratin 14; Belongs to the intermediate filament family. (514 aa)
ATP5F1AATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (560 aa)
FBXO2F-box protein 2. (297 aa)
SDHBSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (280 aa)
ATP5PBATP synthase peripheral stalk-membrane subunit b. (256 aa)
ACEAngiotensin-converting enzyme. (1313 aa)
SUPT16HSPT16 homolog, facilitates chromatin remodeling subunit. (1047 aa)
NOP10NOP10 ribonucleoprotein. (64 aa)
NCOA2Nuclear receptor coactivator. (1473 aa)
ATP5F1BATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (528 aa)
UBE2E3Ubiquitin conjugating enzyme E2 E3; Belongs to the ubiquitin-conjugating enzyme family. (207 aa)
LOC108638252ATP synthase subunit; Mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F1 - containing the extramembraneous catalytic core, and F0 - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F1 is coupled via a rotary mechanism of the central stalk subunits to proto [...] (103 aa)
TCOF1Treacle ribosome biogenesis factor 1. (1451 aa)
SMARCC1SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1. (1093 aa)
VSNL1Visinin like 1. (191 aa)
UBE2G2Ubiquitin conjugating enzyme E2 G2; Belongs to the ubiquitin-conjugating enzyme family. (165 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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