STRINGSTRING
CAV1 CAV1 FGR FGR IFNG IFNG IL10 IL10 SFTPC SFTPC ALB ALB IL4 IL4 CASP3 CASP3 ACTB ACTB CYBB CYBB IL6 IL6 TGFB1 TGFB1 FYN FYN FRK FRK SRC SRC CSF2 CSF2 STAT6 STAT6 ARG1 ARG1 HCK HCK IFIT1 IFIT1 EGFR EGFR LCK LCK
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
FGRTyrosine-protein kinase. (527 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity); Belongs to the type II (or gamma) interferon family. (166 aa)
IL10Interleukin 10. (177 aa)
SFTPCSurfactant protein C. (190 aa)
ALBSerum albumin. (608 aa)
IL4Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4; Belongs to the IL- [...] (135 aa)
CASP3Caspase 3; Belongs to the peptidase C14A family. (275 aa)
ACTBUncharacterized protein. (375 aa)
CYBBCytochrome b-245 beta chain. (570 aa)
IL6Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (237 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
FYNTyrosine-protein kinase. (537 aa)
FRKTyrosine-protein kinase. (515 aa)
SRCTyrosine-protein kinase. (538 aa)
CSF2Granulocyte-macrophage colony stimulating factor. (144 aa)
STAT6Signal transducer and activator of transcription. (841 aa)
ARG1Arginase. (322 aa)
HCKTyrosine-protein kinase. (528 aa)
IFIT1Interferon induced protein with tetratricopeptide repeats 1. (481 aa)
EGFRReceptor protein-tyrosine kinase. (1208 aa)
LCKTyrosine-protein kinase. (509 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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