STRINGSTRING
EGFR EGFR GLUD1 GLUD1 MTHFD1 MTHFD1 SHMT2 SHMT2 PKLR PKLR ENSCHIP00000004162 ENSCHIP00000004162 PSPH PSPH LOC108634030 LOC108634030 SHMT1 SHMT1 MYC MYC TFAM TFAM API5 API5 PKM PKM IFNAR1 IFNAR1 TGFA TGFA PHGDH PHGDH NDUFS6 NDUFS6 GLDC GLDC PRDX4 PRDX4 PSAT1 PSAT1 HTATIP2 HTATIP2 CHCHD2 CHCHD2 GCSH GCSH
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EGFRReceptor protein-tyrosine kinase. (1208 aa)
GLUD1ELFV_dehydrog domain-containing protein; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (561 aa)
MTHFD1Methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1. (935 aa)
SHMT2Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (502 aa)
PKLRPyruvate kinase; Belongs to the pyruvate kinase family. (575 aa)
ENSCHIP00000004162Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (515 aa)
PSPHPhosphoserine phosphatase. (225 aa)
LOC108634030Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. (173 aa)
SHMT1Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (484 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (439 aa)
TFAMTranscription factor A, mitochondrial. (246 aa)
API5Apoptosis inhibitor 5. (524 aa)
PKMPyruvate kinase; Belongs to the pyruvate kinase family. (531 aa)
IFNAR1Interferon alpha and beta receptor subunit 1. (560 aa)
TGFATransforming growth factor alpha. (215 aa)
PHGDHD-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (533 aa)
NDUFS6NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (124 aa)
GLDCGlycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. (1020 aa)
PRDX4Peroxiredoxin 4. (275 aa)
PSAT1Phosphoserine aminotransferase. (370 aa)
HTATIP2HIV-1 Tat interactive protein 2. (242 aa)
CHCHD2Uncharacterized protein. (152 aa)
GCSHGlycine cleavage system protein H. (173 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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