14 items (Capra hircus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MUS81	MUS81 structure-specific endonuclease subunit. (552 aa)
	FAAP24	FA core complex associated protein 24. (215 aa)
	SLX1A	Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. Has a preference for 5'-flap structures, and promotes symmetrical cleavage of static and migrating Holliday junctions (HJs). Resolves HJs by generating two pairs of ligatable, nicked duplex products. (267 aa)
	FANCL	RING-type domain-containing protein. (379 aa)
	USP1	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (782 aa)
	PCNA	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
	RAD51C	RAD51 paralog C. (371 aa)
	FANCM	FA complementation group M. (2043 aa)
	XPA	XPA, DNA damage recognition and repair factor. (273 aa)
	FANCA	FA complementation group A. (1416 aa)
	FANCI	FA complementation group I. (1086 aa)
	FANCD2	FA complementation group D2. (1423 aa)
	ERCC1	ERCC excision repair 1, endonuclease non-catalytic subunit. (294 aa)
	ERCC4	ERCC excision repair 4, endonuclease catalytic subunit. (916 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ERCC1	ERCC4	ENSCHIP00000031141	ENSCHIP00000026065	ERCC excision repair 1, endonuclease non-catalytic subunit.	ERCC excision repair 4, endonuclease catalytic subunit.	0.999
ERCC1	FAAP24	ENSCHIP00000031141	ENSCHIP00000023626	ERCC excision repair 1, endonuclease non-catalytic subunit.	FA core complex associated protein 24.	0.867
ERCC1	FANCA	ENSCHIP00000031141	ENSCHIP00000001913	ERCC excision repair 1, endonuclease non-catalytic subunit.	FA complementation group A.	0.897
ERCC1	FANCD2	ENSCHIP00000031141	ENSCHIP00000032582	ERCC excision repair 1, endonuclease non-catalytic subunit.	FA complementation group D2.	0.927
ERCC1	FANCI	ENSCHIP00000031141	ENSCHIP00000001071	ERCC excision repair 1, endonuclease non-catalytic subunit.	FA complementation group I.	0.893
ERCC1	FANCL	ENSCHIP00000031141	ENSCHIP00000020403	ERCC excision repair 1, endonuclease non-catalytic subunit.	RING-type domain-containing protein.	0.897
ERCC1	FANCM	ENSCHIP00000031141	ENSCHIP00000013958	ERCC excision repair 1, endonuclease non-catalytic subunit.	FA complementation group M.	0.999
ERCC1	MUS81	ENSCHIP00000031141	ENSCHIP00000028466	ERCC excision repair 1, endonuclease non-catalytic subunit.	MUS81 structure-specific endonuclease subunit.	0.968
ERCC1	RAD51C	ENSCHIP00000031141	ENSCHIP00000013986	ERCC excision repair 1, endonuclease non-catalytic subunit.	RAD51 paralog C.	0.536
ERCC1	SLX1A	ENSCHIP00000031141	ENSCHIP00000023499	ERCC excision repair 1, endonuclease non-catalytic subunit.	Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. Has a preference for 5'-flap structures, and promotes symmetrical cleavage of static and migrating Holliday junctions (HJs). Resolves HJs by generating two pairs of ligatable, nicked duplex products.	0.919
ERCC1	USP1	ENSCHIP00000031141	ENSCHIP00000015291	ERCC excision repair 1, endonuclease non-catalytic subunit.	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family.	0.568
ERCC1	XPA	ENSCHIP00000031141	ENSCHIP00000006813	ERCC excision repair 1, endonuclease non-catalytic subunit.	XPA, DNA damage recognition and repair factor.	0.994
ERCC4	ERCC1	ENSCHIP00000026065	ENSCHIP00000031141	ERCC excision repair 4, endonuclease catalytic subunit.	ERCC excision repair 1, endonuclease non-catalytic subunit.	0.999
ERCC4	FAAP24	ENSCHIP00000026065	ENSCHIP00000023626	ERCC excision repair 4, endonuclease catalytic subunit.	FA core complex associated protein 24.	0.969
ERCC4	FANCA	ENSCHIP00000026065	ENSCHIP00000001913	ERCC excision repair 4, endonuclease catalytic subunit.	FA complementation group A.	0.890
ERCC4	FANCD2	ENSCHIP00000026065	ENSCHIP00000032582	ERCC excision repair 4, endonuclease catalytic subunit.	FA complementation group D2.	0.920
ERCC4	FANCI	ENSCHIP00000026065	ENSCHIP00000001071	ERCC excision repair 4, endonuclease catalytic subunit.	FA complementation group I.	0.900
ERCC4	FANCL	ENSCHIP00000026065	ENSCHIP00000020403	ERCC excision repair 4, endonuclease catalytic subunit.	RING-type domain-containing protein.	0.907
ERCC4	FANCM	ENSCHIP00000026065	ENSCHIP00000013958	ERCC excision repair 4, endonuclease catalytic subunit.	FA complementation group M.	0.932
ERCC4	MUS81	ENSCHIP00000026065	ENSCHIP00000028466	ERCC excision repair 4, endonuclease catalytic subunit.	MUS81 structure-specific endonuclease subunit.	0.965