19 items (Capra hircus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CDT1	Chromatin licensing and DNA replication factor 1. (637 aa)
	CASP3	Caspase 3; Belongs to the peptidase C14A family. (275 aa)
	ORC6	Origin recognition complex subunit 6. (252 aa)
	MCM4	DNA helicase; Belongs to the MCM family. (851 aa)
	POLA1	DNA polymerase. (1468 aa)
	CDC45	Cell division cycle 45. (524 aa)
	GMNN	Geminin DNA replication inhibitor. (186 aa)
	POLD1	DNA polymerase. (1115 aa)
	PRIM1	DNA primase; Belongs to the eukaryotic-type primase small subunit family. (401 aa)
	POLE2	DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (518 aa)
	ORC4	Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (436 aa)
	DONSON	Downstream neighbor of SON. (561 aa)
	VCL	Vinculin. (1134 aa)
	POLE	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2281 aa)
	CDC6	Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (562 aa)
	POLD2	DNA polymerase delta 2, accessory subunit. (469 aa)
	GINS1	GINS complex subunit 1. (196 aa)
	MCM5	DNA helicase; Belongs to the MCM family. (734 aa)
	OR6C4	Olfactory receptor. (309 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CASP3	VCL	ENSCHIP00000011490	ENSCHIP00000000453	Caspase 3; Belongs to the peptidase C14A family.	Vinculin.	0.690
CDC45	CDC6	ENSCHIP00000013791	ENSCHIP00000005199	Cell division cycle 45.	Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family.	0.987
CDC45	CDT1	ENSCHIP00000013791	ENSCHIP00000009696	Cell division cycle 45.	Chromatin licensing and DNA replication factor 1.	0.985
CDC45	DONSON	ENSCHIP00000013791	ENSCHIP00000022716	Cell division cycle 45.	Downstream neighbor of SON.	0.571
CDC45	GINS1	ENSCHIP00000013791	ENSCHIP00000006760	Cell division cycle 45.	GINS complex subunit 1.	0.992
CDC45	GMNN	ENSCHIP00000013791	ENSCHIP00000021437	Cell division cycle 45.	Geminin DNA replication inhibitor.	0.805
CDC45	MCM4	ENSCHIP00000013791	ENSCHIP00000018829	Cell division cycle 45.	DNA helicase; Belongs to the MCM family.	0.999
CDC45	MCM5	ENSCHIP00000013791	ENSCHIP00000008177	Cell division cycle 45.	DNA helicase; Belongs to the MCM family.	0.999
CDC45	ORC4	ENSCHIP00000013791	ENSCHIP00000028287	Cell division cycle 45.	Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family.	0.909
CDC45	ORC6	ENSCHIP00000013791	ENSCHIP00000025848	Cell division cycle 45.	Origin recognition complex subunit 6.	0.954
CDC45	POLA1	ENSCHIP00000013791	ENSCHIP00000016749	Cell division cycle 45.	DNA polymerase.	0.984
CDC45	POLD1	ENSCHIP00000013791	ENSCHIP00000019836	Cell division cycle 45.	DNA polymerase.	0.911
CDC45	POLD2	ENSCHIP00000013791	ENSCHIP00000005641	Cell division cycle 45.	DNA polymerase delta 2, accessory subunit.	0.716
CDC45	POLE	ENSCHIP00000013791	ENSCHIP00000003433	Cell division cycle 45.	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.	0.982
CDC45	POLE2	ENSCHIP00000013791	ENSCHIP00000028310	Cell division cycle 45.	DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family.	0.996
CDC45	PRIM1	ENSCHIP00000013791	ENSCHIP00000033299	Cell division cycle 45.	DNA primase; Belongs to the eukaryotic-type primase small subunit family.	0.959
CDC6	CDC45	ENSCHIP00000005199	ENSCHIP00000013791	Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family.	Cell division cycle 45.	0.987
CDC6	CDT1	ENSCHIP00000005199	ENSCHIP00000009696	Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family.	Chromatin licensing and DNA replication factor 1.	0.999
CDC6	DONSON	ENSCHIP00000005199	ENSCHIP00000022716	Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family.	Downstream neighbor of SON.	0.410
CDC6	GINS1	ENSCHIP00000005199	ENSCHIP00000006760	Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family.	GINS complex subunit 1.	0.672