24 items (Capra hircus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

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co-expression

protein homology

Your Input:
	NDUFS7	NADH:ubiquinone oxidoreductase core subunit S7; Belongs to the complex I 20 kDa subunit family. (238 aa)
	EIF4E	Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family. (217 aa)
	RPS6	40S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (255 aa)
	NDUFS8	Uncharacterized protein. (212 aa)
	SDHB	Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (280 aa)
	ACTB	Uncharacterized protein. (375 aa)
	CASP1	Uncharacterized protein; Belongs to the peptidase C14A family. (411 aa)
	NDUFA9	NADH:ubiquinone oxidoreductase subunit A9. (382 aa)
	NDUFB8	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (186 aa)
	NDUFA5	NADH:ubiquinone oxidoreductase subunit A5. (108 aa)
	UQCRC1	Ubiquinol-cytochrome c reductase core protein 1. (480 aa)
	PKM	Pyruvate kinase; Belongs to the pyruvate kinase family. (531 aa)
	PXDN	Peroxidasin. (1525 aa)
	UQCRC2	Ubiquinol-cytochrome c reductase core protein 2; Belongs to the peptidase M16 family. (453 aa)
	NDUFS3	NADH:ubiquinone oxidoreductase core subunit S3; Belongs to the complex I 30 kDa subunit family. (266 aa)
	SDHA	Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (665 aa)
	IRF3	Interferon regulatory factor 3. (418 aa)
	MTOR	Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2550 aa)
	GFAP	Glial fibrillary acidic protein; Belongs to the intermediate filament family. (428 aa)
	VDAC1	Voltage dependent anion channel 1. (283 aa)
	NDUFS2	NADH:ubiquinone oxidoreductase core subunit S2; Belongs to the complex I 49 kDa subunit family. (463 aa)
	NDUFS4	NADH:ubiquinone oxidoreductase subunit S4. (175 aa)
	COX1	Cytochrome c oxidase subunit 1; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...] (514 aa)
	PKLR	Pyruvate kinase; Belongs to the pyruvate kinase family. (575 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTB	CASP1	ENSCHIP00000011080	ENSCHIP00000011226	Uncharacterized protein.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.857
ACTB	COX1	ENSCHIP00000011080	ENSCHIP00000000003	Uncharacterized protein.	Cytochrome c oxidase subunit 1; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...]	0.675
ACTB	EIF4E	ENSCHIP00000011080	ENSCHIP00000005408	Uncharacterized protein.	Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family.	0.712
ACTB	GFAP	ENSCHIP00000011080	ENSCHIP00000028106	Uncharacterized protein.	Glial fibrillary acidic protein; Belongs to the intermediate filament family.	0.868
ACTB	IRF3	ENSCHIP00000011080	ENSCHIP00000018567	Uncharacterized protein.	Interferon regulatory factor 3.	0.793
ACTB	MTOR	ENSCHIP00000011080	ENSCHIP00000021872	Uncharacterized protein.	Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family.	0.734
ACTB	NDUFA9	ENSCHIP00000011080	ENSCHIP00000012017	Uncharacterized protein.	NADH:ubiquinone oxidoreductase subunit A9.	0.427
ACTB	NDUFB8	ENSCHIP00000011080	ENSCHIP00000012486	Uncharacterized protein.	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.	0.501
ACTB	PKM	ENSCHIP00000011080	ENSCHIP00000015417	Uncharacterized protein.	Pyruvate kinase; Belongs to the pyruvate kinase family.	0.744
ACTB	PXDN	ENSCHIP00000011080	ENSCHIP00000015493	Uncharacterized protein.	Peroxidasin.	0.962
ACTB	RPS6	ENSCHIP00000011080	ENSCHIP00000006669	Uncharacterized protein.	40S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family.	0.747
ACTB	SDHA	ENSCHIP00000011080	ENSCHIP00000018522	Uncharacterized protein.	Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).	0.726
ACTB	SDHB	ENSCHIP00000011080	ENSCHIP00000011037	Uncharacterized protein.	Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).	0.571
ACTB	UQCRC2	ENSCHIP00000011080	ENSCHIP00000016436	Uncharacterized protein.	Ubiquinol-cytochrome c reductase core protein 2; Belongs to the peptidase M16 family.	0.471
ACTB	VDAC1	ENSCHIP00000011080	ENSCHIP00000028854	Uncharacterized protein.	Voltage dependent anion channel 1.	0.742
CASP1	ACTB	ENSCHIP00000011226	ENSCHIP00000011080	Uncharacterized protein; Belongs to the peptidase C14A family.	Uncharacterized protein.	0.857
CASP1	GFAP	ENSCHIP00000011226	ENSCHIP00000028106	Uncharacterized protein; Belongs to the peptidase C14A family.	Glial fibrillary acidic protein; Belongs to the intermediate filament family.	0.687
CASP1	IRF3	ENSCHIP00000011226	ENSCHIP00000018567	Uncharacterized protein; Belongs to the peptidase C14A family.	Interferon regulatory factor 3.	0.620
CASP1	PXDN	ENSCHIP00000011226	ENSCHIP00000015493	Uncharacterized protein; Belongs to the peptidase C14A family.	Peroxidasin.	0.780
COX1	ACTB	ENSCHIP00000000003	ENSCHIP00000011080	Cytochrome c oxidase subunit 1; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...]	Uncharacterized protein.	0.675