(12 nodes) (2021) PRSS55 plays an important role in the structural differentiation and energy metabolism of sperm and is required for male fertility in mice. network (Capra hircus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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Your Input:
	ALB	Serum albumin. (608 aa)
	BAX	BCL2 associated X, apoptosis regulator. (192 aa)
	MYH10	Myosin heavy chain 10; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1975 aa)
	BCL2	BH4_2 domain-containing protein. (229 aa)
	CYTB	Cytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis. (379 aa)
	PRSS37	Serine protease 37. (235 aa)
	PRSS55	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (254 aa)
	MYL6B	Myosin light chain 6B. (211 aa)
	ACTB	Uncharacterized protein. (375 aa)
	CASP3	Caspase 3; Belongs to the peptidase C14A family. (275 aa)
	PRSS54	Peptidase S1 domain-containing protein. (327 aa)
	MYH9	Myosin heavy chain 9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1986 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTB	ALB	ENSCHIP00000011080	ENSCHIP00000020234	Uncharacterized protein.	Serum albumin.	0.961
ACTB	BCL2	ENSCHIP00000011080	ENSCHIP00000015831	Uncharacterized protein.	BH4_2 domain-containing protein.	0.940
ACTB	CASP3	ENSCHIP00000011080	ENSCHIP00000011490	Uncharacterized protein.	Caspase 3; Belongs to the peptidase C14A family.	0.996
ACTB	CYTB	ENSCHIP00000011080	ENSCHIP00000000013	Uncharacterized protein.	Cytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.	0.639
ACTB	MYH10	ENSCHIP00000011080	ENSCHIP00000019825	Uncharacterized protein.	Myosin heavy chain 10; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.952
ACTB	MYH9	ENSCHIP00000011080	ENSCHIP00000021370	Uncharacterized protein.	Myosin heavy chain 9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.964
ACTB	MYL6B	ENSCHIP00000011080	ENSCHIP00000002873	Uncharacterized protein.	Myosin light chain 6B.	0.944
ALB	ACTB	ENSCHIP00000020234	ENSCHIP00000011080	Serum albumin.	Uncharacterized protein.	0.961
ALB	BCL2	ENSCHIP00000020234	ENSCHIP00000015831	Serum albumin.	BH4_2 domain-containing protein.	0.866
ALB	CASP3	ENSCHIP00000020234	ENSCHIP00000011490	Serum albumin.	Caspase 3; Belongs to the peptidase C14A family.	0.892
ALB	CYTB	ENSCHIP00000020234	ENSCHIP00000000013	Serum albumin.	Cytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.	0.537
BAX	BCL2	ENSCHIP00000016021	ENSCHIP00000015831	BCL2 associated X, apoptosis regulator.	BH4_2 domain-containing protein.	0.971
BAX	CASP3	ENSCHIP00000016021	ENSCHIP00000011490	BCL2 associated X, apoptosis regulator.	Caspase 3; Belongs to the peptidase C14A family.	0.765
BAX	PRSS55	ENSCHIP00000016021	ENSCHIP00000001189	BCL2 associated X, apoptosis regulator.	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.	0.455
BCL2	ACTB	ENSCHIP00000015831	ENSCHIP00000011080	BH4_2 domain-containing protein.	Uncharacterized protein.	0.940
BCL2	ALB	ENSCHIP00000015831	ENSCHIP00000020234	BH4_2 domain-containing protein.	Serum albumin.	0.866
BCL2	BAX	ENSCHIP00000015831	ENSCHIP00000016021	BH4_2 domain-containing protein.	BCL2 associated X, apoptosis regulator.	0.971
BCL2	CASP3	ENSCHIP00000015831	ENSCHIP00000011490	BH4_2 domain-containing protein.	Caspase 3; Belongs to the peptidase C14A family.	0.977
BCL2	CYTB	ENSCHIP00000015831	ENSCHIP00000000013	BH4_2 domain-containing protein.	Cytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.	0.411
CASP3	ACTB	ENSCHIP00000011490	ENSCHIP00000011080	Caspase 3; Belongs to the peptidase C14A family.	Uncharacterized protein.	0.996