STRINGSTRING
FBH1 FBH1 RAD51 RAD51 BRCA1 BRCA1 HDAC9 HDAC9 UBN1 UBN1 MUS81 MUS81 LOC102189503 LOC102189503 BRCA2 BRCA2 RAD51D RAD51D DNA2 DNA2 HDAC4 HDAC4 ASF1B ASF1B HDAC5 HDAC5 EME1 EME1 PXDN PXDN EXO1 EXO1 HDAC7 HDAC7 AGO1 AGO1 LOC102169981 LOC102169981 LOC102171353 LOC102171353 CENPB CENPB LOC108633916 LOC108633916 LOC106503499 LOC106503499 LOC102180554 LOC102180554 ZGRF1 ZGRF1 LOC102191748 LOC102191748 LOC102185882 LOC102185882 LOC108633554 LOC108633554 LOC102182848 LOC102182848 RAD50 RAD50 LOC108636012 LOC108636012 H3-4 H3-4 LOC108634231 LOC108634231 ASF1A ASF1A RAD52 RAD52
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FBH1F-box DNA helicase 1. (1048 aa)
RAD51DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (339 aa)
BRCA1Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (1843 aa)
HDAC9Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1069 aa)
UBN1Ubinuclein 1. (1131 aa)
MUS81MUS81 structure-specific endonuclease subunit. (552 aa)
LOC102189503Histone H3; Belongs to the histone H3 family. (136 aa)
BRCA2BRCA2 DNA repair associated. (3405 aa)
RAD51DDNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents; Belongs to the RecA family. RAD51 subfamily. (338 aa)
DNA2DNA replication helicase/nuclease 2. (1062 aa)
HDAC4Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1089 aa)
ASF1BUncharacterized protein. (202 aa)
HDAC5Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1142 aa)
EME1Essential meiotic structure-specific endonuclease 1. (580 aa)
PXDNPeroxidasin. (1525 aa)
EXO1Exonuclease 1. (835 aa)
HDAC7Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1062 aa)
AGO1Uncharacterized protein; Belongs to the argonaute family. (916 aa)
LOC102169981Histone domain-containing protein. (136 aa)
LOC102171353Histone H3; Belongs to the histone H3 family. (136 aa)
CENPBCentromere protein B. (600 aa)
LOC108633916Histone H3; Belongs to the histone H3 family. (136 aa)
LOC106503499Histone H3; Belongs to the histone H3 family. (136 aa)
LOC102180554Histone H3; Belongs to the histone H3 family. (136 aa)
ZGRF1Uncharacterized protein. (1855 aa)
LOC102191748Histone domain-containing protein. (136 aa)
LOC102185882Histone H3; Belongs to the histone H3 family. (136 aa)
LOC108633554Histone domain-containing protein. (136 aa)
LOC102182848Histone H3; Belongs to the histone H3 family. (136 aa)
RAD50Zinc-hook domain-containing protein. (1332 aa)
LOC108636012Histone H3; Belongs to the histone H3 family. (136 aa)
H3-4Histone H3; Belongs to the histone H3 family. (136 aa)
LOC108634231Histone H3; Belongs to the histone H3 family. (136 aa)
ASF1AAnti-silencing function 1A histone chaperone. (204 aa)
RAD52RAD52 homolog, DNA repair protein. (416 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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