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CKM CKM GLUL GLUL PFKM PFKM ATP5PD ATP5PD PYGB PYGB OBSCN OBSCN MAP1LC3B MAP1LC3B SLC25A4 SLC25A4 MYH2 MYH2 PYGL PYGL ATP5F1D ATP5F1D PGAM2 PGAM2 NDUFA13 NDUFA13 ANXA2 ANXA2 CASQ1 CASQ1 MYL6B MYL6B TNNT3 TNNT3 DYSF DYSF LOC102176799 LOC102176799 ACTG2 ACTG2 GAPDHS GAPDHS PGK1 PGK1 MYOD1 MYOD1 HSP90B1 HSP90B1 LOC102191741 LOC102191741 ATP5PO ATP5PO LDHB LDHB TNNC2 TNNC2 ATP5F1B ATP5F1B MYH4 MYH4 SIRT1 SIRT1 PYGM PYGM DDIT3 DDIT3 LOC102181016 LOC102181016 ACTA1 ACTA1 GOT2 GOT2 VDAC2 VDAC2 ALDOA ALDOA ACTN3 ACTN3 RHOA RHOA NDUFA9 NDUFA9 CDC42 CDC42 NEB NEB TPM2 TPM2 TFEB TFEB ATP5F1A ATP5F1A RYR1 RYR1 NDUFA4 NDUFA4 NDUFS1 NDUFS1 STX17 STX17 UQCRC1 UQCRC1 MDH1 MDH1 CFL2 CFL2 TPI1 TPI1 PKM PKM PXDN PXDN MYL1 MYL1 TTN TTN TNNI1 TNNI1 UQCRC2 UQCRC2 BAG2 BAG2 BNIP3 BNIP3 VAMP8 VAMP8 HSPA8 HSPA8 ATP5MG ATP5MG FBP2 FBP2 PRKAA1 PRKAA1 TPM3 TPM3 CKB CKB HSP90AB1 HSP90AB1 FOXO3 FOXO3 VCP VCP ATP5F1C ATP5F1C CKMT1A CKMT1A SNAP29 SNAP29 CKMT2 CKMT2 ALB ALB ENO3 ENO3 MYL2 MYL2 TPM1 TPM1 MYH3 MYH3 VDAC3 VDAC3 TRIM72 TRIM72 MYH7 MYH7 ATP5MF ATP5MF LOC108633295 LOC108633295 HSP90AA1 HSP90AA1 GAPDH GAPDH NDUFV1 NDUFV1 CSRP3 CSRP3 COX6B1 COX6B1 VDAC1 VDAC1 MDH2 MDH2 HSPA5 HSPA5 MYLPF MYLPF TCAP TCAP TNNI2 TNNI2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CKMCreatine kinase, M-type; Belongs to the ATP:guanido phosphotransferase family. (381 aa)
GLULGlutamine synthetase. (373 aa)
PFKMATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (838 aa)
ATP5PDATP synthase subunit d, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the cent [...] (162 aa)
PYGBAlpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (846 aa)
OBSCNObscurin, cytoskeletal calmodulin and titin-interacting RhoGEF. (8641 aa)
MAP1LC3BUncharacterized protein. (143 aa)
SLC25A4Solute carrier family 25 member 4; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa)
MYH2Myosin heavy chain 2; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1936 aa)
PYGLAlpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (851 aa)
ATP5F1DATP synthase F1 subunit delta. (168 aa)
PGAM2Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (253 aa)
NDUFA13NADH:ubiquinone oxidoreductase subunit A13. (144 aa)
ANXA2Annexin. (339 aa)
CASQ1Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (397 aa)
MYL6BMyosin light chain 6B. (211 aa)
TNNT3Troponin T3, fast skeletal type. (258 aa)
DYSFDysferlin. (2039 aa)
LOC102176799Glyceraldehyde-3-phosphate dehydrogenase. (333 aa)
ACTG2Actin gamma 2, smooth muscle. (376 aa)
GAPDHSGlyceraldehyde-3-phosphate dehydrogenase. (385 aa)
PGK1Phosphoglycerate kinase. (424 aa)
MYOD1Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (319 aa)
HSP90B1Heat shock protein 90 beta family member 1. (836 aa)
LOC102191741Uncharacterized protein. (152 aa)
ATP5POUncharacterized protein. (196 aa)
LDHBL-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (334 aa)
TNNC2Uncharacterized protein. (160 aa)
ATP5F1BATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (528 aa)
MYH4Myosin heavy chain 4; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1931 aa)
SIRT1Deacetylase sirtuin-type domain-containing protein. (732 aa)
PYGMAlpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (857 aa)
DDIT3DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (168 aa)
LOC102181016Gp_dh_N domain-containing protein; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (318 aa)
ACTA1Uncharacterized protein; Belongs to the actin family. (223 aa)
GOT2Aspartate aminotransferase. (430 aa)
VDAC2Voltage dependent anion channel 2. (294 aa)
ALDOAFructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (416 aa)
ACTN3Actinin alpha 3 (gene/pseudogene). (902 aa)
RHOARas-like protein family member A. (193 aa)
NDUFA9NADH:ubiquinone oxidoreductase subunit A9. (382 aa)
CDC42Uncharacterized protein. (191 aa)
NEBNebulin. (6655 aa)
TPM2Uncharacterized protein; Belongs to the tropomyosin family. (284 aa)
TFEBTranscription factor EB. (478 aa)
ATP5F1AATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (560 aa)
RYR1Ryanodine receptor 1. (5010 aa)
NDUFA4NADH dehydrogenase (Ubiquinone) 1 alpha subcomplex 4. (82 aa)
NDUFS1NADH:ubiquinone oxidoreductase core subunit S1; Belongs to the complex I 75 kDa subunit family. (727 aa)
STX17Syntaxin 17; Belongs to the syntaxin family. (301 aa)
UQCRC1Ubiquinol-cytochrome c reductase core protein 1. (480 aa)
MDH1Malate dehydrogenase. (334 aa)
CFL2Cofilin 2; Belongs to the actin-binding proteins ADF family. (166 aa)
TPI1Triosephosphate isomerase. (295 aa)
PKMPyruvate kinase; Belongs to the pyruvate kinase family. (531 aa)
PXDNPeroxidasin. (1525 aa)
MYL1Myosin light chain 1. (174 aa)
TTNUncharacterized protein. (2149 aa)
TNNI1Troponin I1, slow skeletal type. (187 aa)
UQCRC2Ubiquinol-cytochrome c reductase core protein 2; Belongs to the peptidase M16 family. (453 aa)
BAG2BCL2 associated athanogene 2. (211 aa)
BNIP3BCL2 interacting protein 3. (193 aa)
VAMP8Vesicle associated membrane protein 8. (101 aa)
HSPA8Uncharacterized protein; Belongs to the heat shock protein 70 family. (646 aa)
ATP5MGATP synthase membrane subunit g. (103 aa)
FBP2Fructose-bisphosphatase 2; Belongs to the FBPase class 1 family. (350 aa)
PRKAA1Non-specific serine/threonine protein kinase. (559 aa)
TPM3Tropomyosin 3; Belongs to the tropomyosin family. (290 aa)
CKBCreatine kinase B; Belongs to the ATP:guanido phosphotransferase family. (381 aa)
HSP90AB1Heat shock protein 90 alpha family class B member 1. (724 aa)
FOXO3Forkhead box O3. (672 aa)
VCPValosin containing protein; Belongs to the AAA ATPase family. (816 aa)
ATP5F1CATP synthase subunit gamma. (298 aa)
CKMT1AUncharacterized protein; Belongs to the ATP:guanido phosphotransferase family. (416 aa)
SNAP29Synaptosome associated protein 29. (258 aa)
CKMT2Creatine kinase, mitochondrial 2; Belongs to the ATP:guanido phosphotransferase family. (419 aa)
ALBSerum albumin. (608 aa)
ENO3Enolase 3. (444 aa)
MYL2Myosin light chain 2. (178 aa)
TPM1Uncharacterized protein; Belongs to the tropomyosin family. (284 aa)
MYH3Myosin heavy chain 3; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1940 aa)
VDAC3Uncharacterized protein. (283 aa)
TRIM72Tripartite motif containing 72. (487 aa)
MYH7Myosin heavy chain 7; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1955 aa)
ATP5MFUncharacterized protein. (104 aa)
LOC108633295ZZ-type domain-containing protein. (323 aa)
HSP90AA1Heat shock protein 90 alpha family class A member 1. (733 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase. (333 aa)
NDUFV1NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. (464 aa)
CSRP3Cysteine and glycine rich protein 3. (194 aa)
COX6B1Cytochrome c oxidase subunit 6B1. (99 aa)
VDAC1Voltage dependent anion channel 1. (283 aa)
MDH2Malate dehydrogenase. (338 aa)
HSPA5Heat shock 70kDa protein 5; Belongs to the heat shock protein 70 family. (655 aa)
MYLPFUncharacterized protein. (169 aa)
TCAPUncharacterized protein. (167 aa)
TNNI2Troponin I2, fast skeletal type. (170 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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