STRINGSTRING
HOXC10 HOXC10 HOXA9 HOXA9 CSF1 CSF1 HOXB13 HOXB13 CTNNB1 CTNNB1 CCL2 CCL2 FGFR4 FGFR4 HOXB5 HOXB5 LOC108638461 LOC108638461 LOC108638467 LOC108638467 IL18 IL18 CXCR2 CXCR2 LOC102190602 LOC102190602 EGFR EGFR LOC108633178 LOC108633178 LOC102176598 LOC102176598 STAT3 STAT3 LOC102177285 LOC102177285 FGFR2 FGFR2 HOXB1 HOXB1 HOXB7 HOXB7 LOC102168343 LOC102168343 LOC102175759 LOC102175759 HOXA10 HOXA10 LOC102176878 LOC102176878 HOXB3 HOXB3 IL6 IL6 FGFR1 FGFR1 HOXA13 HOXA13 FGFR3 FGFR3 HOXA5 HOXA5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HOXC10Homeobox C10. (342 aa)
HOXA9Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (279 aa)
CSF1Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...] (554 aa)
HOXB13Homeobox B13. (285 aa)
CTNNB1Catenin beta 1. (781 aa)
CCL2C-C motif chemokine. (98 aa)
FGFR4Fibroblast growth factor receptor. (870 aa)
HOXB5Homeobox B5. (269 aa)
LOC108638461Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (251 aa)
LOC108638467Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (247 aa)
IL18Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (193 aa)
CXCR2G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (359 aa)
LOC102190602Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (251 aa)
EGFRReceptor protein-tyrosine kinase. (1208 aa)
LOC108633178Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (246 aa)
LOC102176598Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (250 aa)
STAT3Signal transducer and activator of transcription. (770 aa)
LOC102177285Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (246 aa)
FGFR2Fibroblast growth factor receptor. (841 aa)
HOXB1Homeobox B1. (302 aa)
HOXB7Homeobox B7. (217 aa)
LOC102168343Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (256 aa)
LOC102175759Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (254 aa)
HOXA10Homeobox A10. (413 aa)
LOC102176878Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (251 aa)
HOXB3Homeobox B3. (426 aa)
IL6Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (237 aa)
FGFR1Fibroblast growth factor receptor. (860 aa)
HOXA13Homeobox A13. (388 aa)
FGFR3Receptor protein-tyrosine kinase. (710 aa)
HOXA5Homeobox A5. (270 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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