node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BDNF | FGF2 | ENSCHIP00000003028 | ENSCHIP00000019134 | Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. | 0.862 |
BDNF | GFAP | ENSCHIP00000003028 | ENSCHIP00000028106 | Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. | Glial fibrillary acidic protein; Belongs to the intermediate filament family. | 0.940 |
BDNF | INS | ENSCHIP00000003028 | ENSCHIP00000007610 | Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. | Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | 0.878 |
BDNF | NES | ENSCHIP00000003028 | ENSCHIP00000032395 | Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. | Nestin; Belongs to the intermediate filament family. | 0.915 |
BDNF | NTN1 | ENSCHIP00000003028 | ENSCHIP00000023624 | Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. | Netrin 1. | 0.677 |
BDNF | OLIG2 | ENSCHIP00000003028 | ENSCHIP00000003324 | Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. | Oligodendrocyte transcription factor 2. | 0.741 |
BDNF | OTX2 | ENSCHIP00000003028 | ENSCHIP00000008215 | Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. | Homeobox domain-containing protein. | 0.559 |
BDNF | PDGFRA | ENSCHIP00000003028 | ENSCHIP00000002297 | Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. | Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. | 0.856 |
BDNF | PVALB | ENSCHIP00000003028 | ENSCHIP00000029682 | Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. | Parvalbumin; Belongs to the parvalbumin family. | 0.841 |
BDNF | SOX10 | ENSCHIP00000003028 | ENSCHIP00000022016 | Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. | SRY-box transcription factor 10. | 0.575 |
CLDN11 | OLIG2 | ENSCHIP00000007680 | ENSCHIP00000003324 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. | Oligodendrocyte transcription factor 2. | 0.547 |
CLDN11 | SOX10 | ENSCHIP00000007680 | ENSCHIP00000022016 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. | SRY-box transcription factor 10. | 0.519 |
FGF2 | BDNF | ENSCHIP00000019134 | ENSCHIP00000003028 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. | Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. | 0.862 |
FGF2 | GFAP | ENSCHIP00000019134 | ENSCHIP00000028106 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. | Glial fibrillary acidic protein; Belongs to the intermediate filament family. | 0.791 |
FGF2 | INS | ENSCHIP00000019134 | ENSCHIP00000007610 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. | Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | 0.876 |
FGF2 | NES | ENSCHIP00000019134 | ENSCHIP00000032395 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. | Nestin; Belongs to the intermediate filament family. | 0.866 |
FGF2 | OLIG2 | ENSCHIP00000019134 | ENSCHIP00000003324 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. | Oligodendrocyte transcription factor 2. | 0.721 |
FGF2 | OTX2 | ENSCHIP00000019134 | ENSCHIP00000008215 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. | Homeobox domain-containing protein. | 0.599 |
FGF2 | PDGFRA | ENSCHIP00000019134 | ENSCHIP00000002297 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. | Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. | 0.947 |
FGF2 | SOX10 | ENSCHIP00000019134 | ENSCHIP00000022016 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. | SRY-box transcription factor 10. | 0.605 |