STRINGSTRING
PLIN2 PLIN2 HSPB1 HSPB1 PXDN PXDN GSR GSR TXNIP TXNIP FASN FASN SDC1 SDC1 ALB ALB FTH1 FTH1 GPX6 GPX6 LEP LEP CA9 CA9 MTOR MTOR ENSCHIP00000023849 ENSCHIP00000023849 TF TF AASDH AASDH GAPDH GAPDH ACSL1 ACSL1 GPX8 GPX8 FABP7 FABP7 GPX7 GPX7 LYVE1 LYVE1 FABP4 FABP4 LOC102168954 LOC102168954 PRDX5 PRDX5 ACTB ACTB TXN TXN
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PLIN2Perilipin; Belongs to the perilipin family. (378 aa)
HSPB1Heat shock protein family B (small) member 1; Belongs to the small heat shock protein (HSP20) family. (201 aa)
PXDNPeroxidasin. (1525 aa)
GSRGlutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (519 aa)
TXNIPThioredoxin interacting protein. (391 aa)
FASNFatty acid synthase; Fatty acid synthetase catalyzes the formation of long-chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. This multifunctional protein has 7 catalytic activities as an acyl carrier protein. (2755 aa)
SDC1Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (312 aa)
ALBSerum albumin. (608 aa)
FTH1Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (181 aa)
GPX6Glutathione peroxidase; Belongs to the glutathione peroxidase family. (223 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways (By similarity). In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, inc [...] (192 aa)
CA9Carbonic anhydrase 9; Belongs to the alpha-carbonic anhydrase family. (445 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2550 aa)
ENSCHIP00000023849Glutathione peroxidase; Belongs to the glutathione peroxidase family. (177 aa)
TFTransferrin; Belongs to the transferrin family. (698 aa)
AASDHAminoadipate-semialdehyde dehydrogenase. (1106 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase. (333 aa)
ACSL1Acyl-CoA synthetase long chain family member 1. (719 aa)
GPX8Glutathione peroxidase; Belongs to the glutathione peroxidase family. (209 aa)
FABP7Fatty acid binding protein 7; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (132 aa)
GPX7Glutathione peroxidase; Belongs to the glutathione peroxidase family. (186 aa)
LYVE1Lymphatic vessel endothelial hyaluronan receptor 1. (322 aa)
FABP4Fatty acid binding protein 4; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (132 aa)
LOC102168954Glutathione peroxidase; Belongs to the glutathione peroxidase family. (219 aa)
PRDX5Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. (216 aa)
ACTBUncharacterized protein. (375 aa)
TXNThioredoxin; Belongs to the thioredoxin family. (105 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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