STRINGSTRING
PRPF38A PRPF38A NFYC NFYC FANCC FANCC MUS81 MUS81 HLTF HLTF DNA2 DNA2 SMARCAL1 SMARCAL1 ZRANB3 ZRANB3 FANCD2 FANCD2 RAD51 RAD51 ZFP69 ZFP69 RIMS3 RIMS3 FEN1 FEN1 LOC108633924 LOC108633924 MYBL2 MYBL2 BLM BLM CENPA CENPA H2AX H2AX EXO1 EXO1 WRN WRN SLX4 SLX4 FANCA FANCA EXO5 EXO5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PRPF38APre-mRNA processing factor 38A. (312 aa)
NFYCNuclear transcription factor Y subunit gamma. (335 aa)
FANCCFanconi anemia group C protein homolog; DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Upon IFNG induction, may facilitate STAT1 activation by recruiting STAT1 to IFNGR1. (568 aa)
MUS81MUS81 structure-specific endonuclease subunit. (552 aa)
HLTFHelicase like transcription factor. (1011 aa)
DNA2DNA replication helicase/nuclease 2. (1062 aa)
SMARCAL1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1; Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily. (930 aa)
ZRANB3Zinc finger RANBP2-type containing 3. (1070 aa)
FANCD2FA complementation group D2. (1423 aa)
RAD51DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (339 aa)
ZFP69ZFP69 zinc finger protein. (524 aa)
RIMS3Regulating synaptic membrane exocytosis 3. (308 aa)
FEN1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (380 aa)
LOC108633924Histone domain-containing protein. (138 aa)
MYBL2MYB proto-oncogene like 2. (686 aa)
BLMBLM RecQ like helicase. (1429 aa)
CENPACentromere protein A. (138 aa)
H2AXHistone H2A; Belongs to the histone H2A family. (143 aa)
EXO1Exonuclease 1. (835 aa)
WRNWRN RecQ like helicase. (1405 aa)
SLX4SLX4 structure-specific endonuclease subunit. (1752 aa)
FANCAFA complementation group A. (1416 aa)
EXO5Exonuclease 5. (370 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.