STRINGSTRING
ESM1 ESM1 SLC45A3 SLC45A3 ITM2A ITM2A CCNB2 CCNB2 HK1 HK1 ASNS ASNS VWF VWF GPIHBP1 GPIHBP1 HK2 HK2 MYH11 MYH11 GJA5 GJA5 HKDC1 HKDC1 LOC102182127 LOC102182127 AQP1 AQP1 SLC1A5 SLC1A5 BMX BMX EFNB2 EFNB2 MTOR MTOR SLC7A5 SLC7A5 PHGDH PHGDH PDGFB PDGFB SLC1A4 SLC1A4 LYVE1 LYVE1 CCND2 CCND2 TP53 TP53 HK3 HK3 PSAT1 PSAT1 NR2F2 NR2F2 SEMA3G SEMA3G LOC102174895 LOC102174895 EPHB4 EPHB4 HEY1 HEY1 ATF4 ATF4 ATF3 ATF3 MYL9 MYL9 DLL4 DLL4 CDH5 CDH5 SEMA3A SEMA3A SLC7A1 SLC7A1 FBLN5 FBLN5 FOXO1 FOXO1 SEMA3D SEMA3D PSPH PSPH MB MB TNFAIP2 TNFAIP2 SHMT2 SHMT2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ESM1Endothelial cell specific molecule 1. (184 aa)
SLC45A3Solute carrier family 45 member 3. (550 aa)
ITM2AIntegral membrane protein 2A. (230 aa)
CCNB2Cyclin B2; Belongs to the cyclin family. (398 aa)
HK1Hexokinase 1. (945 aa)
ASNSAsparagine synthetase [glutamine-hydrolyzing]. (561 aa)
VWFVon Willebrand factor. (2819 aa)
GPIHBP1Uncharacterized protein. (92 aa)
HK2Hexokinase 2. (917 aa)
MYH11Myosin heavy chain 11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1972 aa)
GJA5Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (359 aa)
HKDC1Hexokinase domain containing 1. (918 aa)
LOC102182127Clusterin; Functions as extracellular chaperone that prevents aggregation of non native proteins. Prevents stress-induced aggregation of blood plasma proteins. (439 aa)
AQP1Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (271 aa)
SLC1A5Amino acid transporter. (530 aa)
BMXTyrosine-protein kinase. (655 aa)
EFNB2Ephrin B2; Belongs to the ephrin family. (335 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2550 aa)
SLC7A5Solute carrier family 7 member 5. (505 aa)
PHGDHD-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (533 aa)
PDGFBPlatelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (241 aa)
SLC1A4Solute carrier family 1 member 4. (527 aa)
LYVE1Lymphatic vessel endothelial hyaluronan receptor 1. (322 aa)
CCND2Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (292 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (382 aa)
HK3Hexokinase 3. (924 aa)
PSAT1Phosphoserine aminotransferase. (370 aa)
NR2F2Nuclear receptor subfamily 2 group F member 2. (419 aa)
SEMA3GSemaphorin 3G; Belongs to the semaphorin family. (769 aa)
LOC102174895Uncharacterized protein. (735 aa)
EPHB4EPH receptor B4. (993 aa)
HEY1Hes related family bHLH transcription factor with YRPW motif 1. (304 aa)
ATF4Activating transcription factor 4. (352 aa)
ATF3Activating transcription factor 3. (181 aa)
MYL9Myosin light chain 9. (172 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (701 aa)
CDH5Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. (783 aa)
SEMA3ASemaphorin 3A; Belongs to the semaphorin family. (772 aa)
SLC7A1Solute carrier family 7 member 1. (629 aa)
FBLN5Fibulin 5. (448 aa)
FOXO1Forkhead box O1. (668 aa)
SEMA3DSemaphorin 3D; Belongs to the semaphorin family. (775 aa)
PSPHPhosphoserine phosphatase. (225 aa)
MBMyoglobin; Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles. (154 aa)
TNFAIP2Uncharacterized protein. (695 aa)
SHMT2Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (502 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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