46 items (Capra hircus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ANXA7	Annexin. (485 aa)
	CSN2	Beta-casein; Important role in determination of the surface properties of the casein micelles. (228 aa)
	STAT5A	Signal transducer and activator of transcription. (810 aa)
	BTN1A1	Butyrophilin subfamily 1 member A1. (526 aa)
	TLR6	Toll-like receptor. (966 aa)
	SLC20A2	Phosphate transporter; Sodium-phosphate symporter which plays a fundamental housekeeping role in phosphate transport. Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family. (645 aa)
	CIDEA	CIDE-N domain-containing protein. (219 aa)
	IL21R	Interleukin 21 receptor. (531 aa)
	IGF1R	Tyrosine-protein kinase receptor. (1367 aa)
	CD36	Uncharacterized protein; Belongs to the CD36 family. (472 aa)
	STAT6	Signal transducer and activator of transcription. (841 aa)
	F2RL1	F2R like trypsin receptor 1. (397 aa)
	SLC35D1	Solute carrier family 35 member D1. (355 aa)
	STAT5B	Signal transducer and activator of transcription. (808 aa)
	CXCL9	C-X-C motif chemokine. (125 aa)
	SLC35C1	Solute carrier family 35 member C1. (372 aa)
	LEP	Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways (By similarity). In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, inc [...] (192 aa)
	SLC20A1	Phosphate transporter; Sodium-phosphate symporter which plays a fundamental housekeeping role in phosphate transport. Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family. (681 aa)
	CXCL16	Uncharacterized protein. (252 aa)
	TYK2	Tyrosine-protein kinase. (1186 aa)
	FASN	Fatty acid synthase; Fatty acid synthetase catalyzes the formation of long-chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. This multifunctional protein has 7 catalytic activities as an acyl carrier protein. (2755 aa)
	SLC35B2	Solute carrier family 35 member B2. (437 aa)
	LOC102177285	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (246 aa)
	PLEK	Pleckstrin. (356 aa)
	CXCL11	C-X-C motif chemokine. (87 aa)
	CXCL13	C-X-C motif chemokine. (109 aa)
	SLC35G1	Solute carrier family 35 member G1. (365 aa)
	CXCL10	C-X-C motif chemokine. (102 aa)
	RPLP0	60S acidic ribosomal protein P0; Ribosomal protein P0 is the functional equivalent of E.coli protein L10. (318 aa)
	IL27RA	Interleukin 27 receptor subunit alpha. (655 aa)
	PAEP	Beta-lactoglobulin; Primary component of whey, it binds retinol and is probably involved in the transport of that molecule; Belongs to the calycin superfamily. Lipocalin family. (219 aa)
	PLIN2	Perilipin; Belongs to the perilipin family. (378 aa)
	SLC37A2	Solute carrier family 37 member 2. (505 aa)
	SLC35C2	Solute carrier family 35 member C2. (365 aa)
	SLC35E3	Solute carrier family 35 member E3. (313 aa)
	JAK1	Tyrosine-protein kinase. (1159 aa)
	PIGR	Polymeric immunoglobulin receptor. (758 aa)
	INS	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (105 aa)
	THRSP	Thyroid hormone responsive. (150 aa)
	EEF1A1	Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (462 aa)
	STAT1	Signal transducer and activator of transcription. (834 aa)
	JAK3	Tyrosine-protein kinase. (1138 aa)
	CXCL14	C-X-C motif chemokine ligand 14. (99 aa)
	SLC35E1	Solute carrier family 35 member E1. (412 aa)
	FABP4	Fatty acid binding protein 4; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (132 aa)
	JAK2	Tyrosine-protein kinase. (1132 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANXA7	INS	ENSCHIP00000000188	ENSCHIP00000007610	Annexin.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.470
ANXA7	LEP	ENSCHIP00000000188	ENSCHIP00000021235	Annexin.	Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways (By similarity). In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, inc [...]	0.420
BTN1A1	CD36	ENSCHIP00000025694	ENSCHIP00000030240	Butyrophilin subfamily 1 member A1.	Uncharacterized protein; Belongs to the CD36 family.	0.546
BTN1A1	CIDEA	ENSCHIP00000025694	ENSCHIP00000028243	Butyrophilin subfamily 1 member A1.	CIDE-N domain-containing protein.	0.495
BTN1A1	CSN2	ENSCHIP00000025694	ENSCHIP00000024801	Butyrophilin subfamily 1 member A1.	Beta-casein; Important role in determination of the surface properties of the casein micelles.	0.819
BTN1A1	FABP4	ENSCHIP00000025694	ENSCHIP00000004118	Butyrophilin subfamily 1 member A1.	Fatty acid binding protein 4; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.	0.549
BTN1A1	FASN	ENSCHIP00000025694	ENSCHIP00000019407	Butyrophilin subfamily 1 member A1.	Fatty acid synthase; Fatty acid synthetase catalyzes the formation of long-chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. This multifunctional protein has 7 catalytic activities as an acyl carrier protein.	0.628
BTN1A1	PAEP	ENSCHIP00000025694	ENSCHIP00000012525	Butyrophilin subfamily 1 member A1.	Beta-lactoglobulin; Primary component of whey, it binds retinol and is probably involved in the transport of that molecule; Belongs to the calycin superfamily. Lipocalin family.	0.445
BTN1A1	PLIN2	ENSCHIP00000025694	ENSCHIP00000011815	Butyrophilin subfamily 1 member A1.	Perilipin; Belongs to the perilipin family.	0.744
CD36	BTN1A1	ENSCHIP00000030240	ENSCHIP00000025694	Uncharacterized protein; Belongs to the CD36 family.	Butyrophilin subfamily 1 member A1.	0.546
CD36	CIDEA	ENSCHIP00000030240	ENSCHIP00000028243	Uncharacterized protein; Belongs to the CD36 family.	CIDE-N domain-containing protein.	0.455
CD36	FABP4	ENSCHIP00000030240	ENSCHIP00000004118	Uncharacterized protein; Belongs to the CD36 family.	Fatty acid binding protein 4; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.	0.825
CD36	FASN	ENSCHIP00000030240	ENSCHIP00000019407	Uncharacterized protein; Belongs to the CD36 family.	Fatty acid synthase; Fatty acid synthetase catalyzes the formation of long-chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. This multifunctional protein has 7 catalytic activities as an acyl carrier protein.	0.789
CD36	INS	ENSCHIP00000030240	ENSCHIP00000007610	Uncharacterized protein; Belongs to the CD36 family.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.745
CD36	LEP	ENSCHIP00000030240	ENSCHIP00000021235	Uncharacterized protein; Belongs to the CD36 family.	Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways (By similarity). In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, inc [...]	0.671
CD36	PLIN2	ENSCHIP00000030240	ENSCHIP00000011815	Uncharacterized protein; Belongs to the CD36 family.	Perilipin; Belongs to the perilipin family.	0.765
CD36	TLR6	ENSCHIP00000030240	ENSCHIP00000025720	Uncharacterized protein; Belongs to the CD36 family.	Toll-like receptor.	0.977
CIDEA	BTN1A1	ENSCHIP00000028243	ENSCHIP00000025694	CIDE-N domain-containing protein.	Butyrophilin subfamily 1 member A1.	0.495
CIDEA	CD36	ENSCHIP00000028243	ENSCHIP00000030240	CIDE-N domain-containing protein.	Uncharacterized protein; Belongs to the CD36 family.	0.455
CIDEA	FABP4	ENSCHIP00000028243	ENSCHIP00000004118	CIDE-N domain-containing protein.	Fatty acid binding protein 4; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.	0.717