12 items (Capra hircus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PSPH	Phosphoserine phosphatase. (225 aa)
	NCK2	Cytoplasmic protein. (376 aa)
	NCK1	Cytoplasmic protein. (377 aa)
	ACTB	Uncharacterized protein. (375 aa)
	ACTA2	Actin alpha 2, smooth muscle. (377 aa)
	PHGDH	D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (533 aa)
	EGFR	Receptor protein-tyrosine kinase. (1208 aa)
	PGAM1	Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (254 aa)
	PSAT1	Phosphoserine aminotransferase. (370 aa)
	FOXM1	Fork-head domain-containing protein. (763 aa)
	SIRT6	Sirtuin 6. (335 aa)
	KRAS	KRAS proto-oncogene, GTPase. (189 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTA2	PGAM1	ENSCHIP00000018506	ENSCHIP00000026849	Actin alpha 2, smooth muscle.	Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily.	0.495
ACTB	EGFR	ENSCHIP00000011080	ENSCHIP00000022759	Uncharacterized protein.	Receptor protein-tyrosine kinase.	0.891
ACTB	FOXM1	ENSCHIP00000011080	ENSCHIP00000030834	Uncharacterized protein.	Fork-head domain-containing protein.	0.653
ACTB	KRAS	ENSCHIP00000011080	ENSCHIP00000032733	Uncharacterized protein.	KRAS proto-oncogene, GTPase.	0.795
ACTB	NCK1	ENSCHIP00000011080	ENSCHIP00000009805	Uncharacterized protein.	Cytoplasmic protein.	0.880
ACTB	NCK2	ENSCHIP00000011080	ENSCHIP00000006571	Uncharacterized protein.	Cytoplasmic protein.	0.856
ACTB	SIRT6	ENSCHIP00000011080	ENSCHIP00000031566	Uncharacterized protein.	Sirtuin 6.	0.522
EGFR	ACTB	ENSCHIP00000022759	ENSCHIP00000011080	Receptor protein-tyrosine kinase.	Uncharacterized protein.	0.891
EGFR	FOXM1	ENSCHIP00000022759	ENSCHIP00000030834	Receptor protein-tyrosine kinase.	Fork-head domain-containing protein.	0.538
EGFR	KRAS	ENSCHIP00000022759	ENSCHIP00000032733	Receptor protein-tyrosine kinase.	KRAS proto-oncogene, GTPase.	0.995
EGFR	NCK1	ENSCHIP00000022759	ENSCHIP00000009805	Receptor protein-tyrosine kinase.	Cytoplasmic protein.	0.842
EGFR	NCK2	ENSCHIP00000022759	ENSCHIP00000006571	Receptor protein-tyrosine kinase.	Cytoplasmic protein.	0.811
FOXM1	ACTB	ENSCHIP00000030834	ENSCHIP00000011080	Fork-head domain-containing protein.	Uncharacterized protein.	0.653
FOXM1	EGFR	ENSCHIP00000030834	ENSCHIP00000022759	Fork-head domain-containing protein.	Receptor protein-tyrosine kinase.	0.538
FOXM1	PHGDH	ENSCHIP00000030834	ENSCHIP00000019405	Fork-head domain-containing protein.	D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.500
KRAS	ACTB	ENSCHIP00000032733	ENSCHIP00000011080	KRAS proto-oncogene, GTPase.	Uncharacterized protein.	0.795
KRAS	EGFR	ENSCHIP00000032733	ENSCHIP00000022759	KRAS proto-oncogene, GTPase.	Receptor protein-tyrosine kinase.	0.995
NCK1	ACTB	ENSCHIP00000009805	ENSCHIP00000011080	Cytoplasmic protein.	Uncharacterized protein.	0.880
NCK1	EGFR	ENSCHIP00000009805	ENSCHIP00000022759	Cytoplasmic protein.	Receptor protein-tyrosine kinase.	0.842
NCK1	NCK2	ENSCHIP00000009805	ENSCHIP00000006571	Cytoplasmic protein.	Cytoplasmic protein.	0.967