STRINGSTRING
MMUT MMUT ARHGAP35 ARHGAP35 TP53 TP53 GNAT1 GNAT1 CTNNB1 CTNNB1 AXIN1 AXIN1 AGO2 AGO2 HMGA1 HMGA1 ABCB5 ABCB5 TNK2 TNK2 PXDN PXDN MMP9 MMP9 NOP2 NOP2 ALB ALB USP39 USP39 TRIM65 TRIM65 GAPDH GAPDH
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MMUTMethylmalonyl-CoA mutase. (771 aa)
ARHGAP35Rho GTPase activating protein 35. (1500 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (382 aa)
GNAT1G protein subunit alpha transducin 1. (350 aa)
CTNNB1Catenin beta 1. (781 aa)
AXIN1Axin 1. (867 aa)
AGO2Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] (860 aa)
HMGA1High mobility group AT-hook 1. (105 aa)
ABCB5ATP binding cassette subfamily B member 5. (1250 aa)
TNK2Tyrosine kinase non receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1086 aa)
PXDNPeroxidasin. (1525 aa)
MMP9Uncharacterized protein. (709 aa)
NOP2SAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (823 aa)
ALBSerum albumin. (608 aa)
USP39Ubiquitin specific peptidase 39. (565 aa)
TRIM65Tripartite motif containing 65. (511 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase. (333 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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