STRINGSTRING
IL13 IL13 LDH-A LDH-A IL10 IL10 BCL2 BCL2 RHOA RHOA CASP3 CASP3 ACTB ACTB IL6 IL6 SIRT1 SIRT1 SOD2 SOD2 CD9 CD9 PTEN PTEN CD63 CD63 GAPDH GAPDH GAP43 GAP43 IGF1R IGF1R IGF1 IGF1 ALB ALB MTOR MTOR
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
IL13Interleukin 13. (131 aa)
LDH-AL-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (361 aa)
IL10Interleukin 10. (177 aa)
BCL2BH4_2 domain-containing protein. (229 aa)
RHOARas-like protein family member A. (193 aa)
CASP3Caspase 3; Belongs to the peptidase C14A family. (275 aa)
ACTBUncharacterized protein. (375 aa)
IL6Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (237 aa)
SIRT1Deacetylase sirtuin-type domain-containing protein. (732 aa)
SOD2Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (222 aa)
CD9Tetraspanin. (226 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (402 aa)
CD63Tetraspanin. (237 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase. (333 aa)
GAP43Growth associated protein 43. (238 aa)
IGF1RTyrosine-protein kinase receptor. (1367 aa)
IGF1Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...] (188 aa)
ALBSerum albumin. (608 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2550 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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