STRINGSTRING
SPRY4 SPRY4 E2F2 E2F2 TMPO TMPO HK2 HK2 ACTB ACTB WNT7B WNT7B ZEB1 ZEB1 MTOR MTOR GAPDH GAPDH MMUT MMUT EBF1 EBF1 TP53 TP53 CTNNB1 CTNNB1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SPRY4Sprouty RTK signaling antagonist 4. (299 aa)
E2F2E2F transcription factor 2. (437 aa)
TMPOThymopoietin. (689 aa)
HK2Hexokinase 2. (917 aa)
ACTBUncharacterized protein. (375 aa)
WNT7BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (416 aa)
ZEB1Zinc finger E-box binding homeobox 1. (1127 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2550 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase. (333 aa)
MMUTMethylmalonyl-CoA mutase. (771 aa)
EBF1EBF transcription factor 1. (490 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (382 aa)
CTNNB1Catenin beta 1. (781 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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