52 items (Capra hircus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	EFNB3	Ephrin B3; Belongs to the ephrin family. (340 aa)
	ATP5F1D	ATP synthase F1 subunit delta. (168 aa)
	DPYSL2	Dihydropyrimidinase like 2. (677 aa)
	SLC25A4	Solute carrier family 25 member 4; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa)
	ATP5PD	ATP synthase subunit d, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the cent [...] (162 aa)
	PFN1	Profilin; Belongs to the profilin family. (140 aa)
	PLP1	Proteolipid protein 1. (277 aa)
	HAPLN2	Hyaluronan and proteoglycan link protein 2. (340 aa)
	PAFAH1B1	Platelet-activating factor acetylhydrolase IB subunit alpha; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ven [...] (410 aa)
	PEA15	DED domain-containing protein. (130 aa)
	STMN1	Stathmin; Belongs to the stathmin family. (149 aa)
	PFDN5-2	Uncharacterized protein. (156 aa)
	NDUFV1	NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. (464 aa)
	PFDN2	Uncharacterized protein. (154 aa)
	ARHGDIA	Rho GDP dissociation inhibitor alpha. (204 aa)
	DCTN2	Dynactin subunit 2. (406 aa)
	GSN	Gelsolin. (785 aa)
	PFDN6	Uncharacterized protein. (129 aa)
	PFDN5	Uncharacterized protein. (154 aa)
	SIRT2	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (390 aa)
	ATP5F1C	ATP synthase subunit gamma. (298 aa)
	ENPP2	Ectonucleotide pyrophosphatase/phosphodiesterase 2. (884 aa)
	DYNLRB1	Dynein light chain roadblock; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. (97 aa)
	BIN1	Bridging integrator 1. (587 aa)
	CNTN2	Contactin 2. (1046 aa)
	ATP5MG	ATP synthase membrane subunit g. (103 aa)
	ANLN	Anillin actin binding protein. (1148 aa)
	ERMN	Ermin. (282 aa)
	SIRT7	Sirtuin 7. (405 aa)
	PRDX6	Thioredoxin domain-containing protein. (224 aa)
	CFL2	Cofilin 2; Belongs to the actin-binding proteins ADF family. (166 aa)
	SIRT3	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (333 aa)
	UQCRC1	Ubiquinol-cytochrome c reductase core protein 1. (480 aa)
	NDUFA5	NADH:ubiquinone oxidoreductase subunit A5. (108 aa)
	BCAS1	Breast carcinoma amplified sequence 1. (569 aa)
	CDC42	Uncharacterized protein. (191 aa)
	RHOA	Ras-like protein family member A. (193 aa)
	FSCN1	Fascin. (493 aa)
	RHOG	Ras homolog family member G. (191 aa)
	TPPP	Tubulin polymerization promoting protein. (221 aa)
	RHOB	RhoB. (196 aa)
	ATP5PB	ATP synthase peripheral stalk-membrane subunit b. (256 aa)
	FNTA	Uncharacterized protein. (378 aa)
	CLIC4	Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (253 aa)
	BCAN	Brevican. (910 aa)
	SIRT1	Deacetylase sirtuin-type domain-containing protein. (732 aa)
	MAG	Myelin associated glycoprotein. (626 aa)
	CNDP1	Carnosine dipeptidase 1. (509 aa)
	CRK	CRK proto-oncogene, adaptor protein. (304 aa)
	OLIG2	Oligodendrocyte transcription factor 2. (329 aa)
	SLC25A5	Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa)
	SIRT4	NAD-dependent protein lipoamidase sirtuin-4, mitochondrial; Acts as NAD-dependent protein lipoamidase, ADP-ribosyl transferase and deacetylase. Catalyzes more efficiently removal of lipoyl- and biotinyl- than acetyl-lysine modifications. Inhibits the pyruvate dehydrogenase complex (PDH) activity via the enzymatic hydrolysis of the lipoamide cofactor from the E2 component, DLAT, in a phosphorylation-independent manner. Catalyzes the transfer of ADP- ribosyl groups onto target proteins, including mitochondrial GLUD1, inhibiting GLUD1 enzyme activity. Acts as a negative regulator of mitoc [...] (315 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANLN	CDC42	ENSCHIP00000017037	ENSCHIP00000012064	Anillin actin binding protein.	Uncharacterized protein.	0.481
ANLN	RHOA	ENSCHIP00000017037	ENSCHIP00000011951	Anillin actin binding protein.	Ras-like protein family member A.	0.769
ANLN	RHOB	ENSCHIP00000017037	ENSCHIP00000010080	Anillin actin binding protein.	RhoB.	0.725
ANLN	RHOG	ENSCHIP00000017037	ENSCHIP00000011071	Anillin actin binding protein.	Ras homolog family member G.	0.570
ARHGDIA	CDC42	ENSCHIP00000024498	ENSCHIP00000012064	Rho GDP dissociation inhibitor alpha.	Uncharacterized protein.	0.997
ARHGDIA	CFL2	ENSCHIP00000024498	ENSCHIP00000014949	Rho GDP dissociation inhibitor alpha.	Cofilin 2; Belongs to the actin-binding proteins ADF family.	0.455
ARHGDIA	MAG	ENSCHIP00000024498	ENSCHIP00000006859	Rho GDP dissociation inhibitor alpha.	Myelin associated glycoprotein.	0.552
ARHGDIA	RHOA	ENSCHIP00000024498	ENSCHIP00000011951	Rho GDP dissociation inhibitor alpha.	Ras-like protein family member A.	0.999
ARHGDIA	RHOB	ENSCHIP00000024498	ENSCHIP00000010080	Rho GDP dissociation inhibitor alpha.	RhoB.	0.944
ARHGDIA	RHOG	ENSCHIP00000024498	ENSCHIP00000011071	Rho GDP dissociation inhibitor alpha.	Ras homolog family member G.	0.740
ATP5F1C	ATP5F1D	ENSCHIP00000019249	ENSCHIP00000033869	ATP synthase subunit gamma.	ATP synthase F1 subunit delta.	0.999
ATP5F1C	ATP5MG	ENSCHIP00000019249	ENSCHIP00000017212	ATP synthase subunit gamma.	ATP synthase membrane subunit g.	0.986
ATP5F1C	ATP5PB	ENSCHIP00000019249	ENSCHIP00000009371	ATP synthase subunit gamma.	ATP synthase peripheral stalk-membrane subunit b.	0.999
ATP5F1C	ATP5PD	ENSCHIP00000019249	ENSCHIP00000031774	ATP synthase subunit gamma.	ATP synthase subunit d, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the cent [...]	0.998
ATP5F1C	NDUFA5	ENSCHIP00000019249	ENSCHIP00000013530	ATP synthase subunit gamma.	NADH:ubiquinone oxidoreductase subunit A5.	0.835
ATP5F1C	NDUFV1	ENSCHIP00000019249	ENSCHIP00000026656	ATP synthase subunit gamma.	NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain.	0.945
ATP5F1C	SLC25A4	ENSCHIP00000019249	ENSCHIP00000032937	ATP synthase subunit gamma.	Solute carrier family 25 member 4; Belongs to the mitochondrial carrier (TC 2.A.29) family.	0.572
ATP5F1C	UQCRC1	ENSCHIP00000019249	ENSCHIP00000013966	ATP synthase subunit gamma.	Ubiquinol-cytochrome c reductase core protein 1.	0.916
ATP5F1D	ATP5F1C	ENSCHIP00000033869	ENSCHIP00000019249	ATP synthase F1 subunit delta.	ATP synthase subunit gamma.	0.999
ATP5F1D	ATP5MG	ENSCHIP00000033869	ENSCHIP00000017212	ATP synthase F1 subunit delta.	ATP synthase membrane subunit g.	0.999