STRINGSTRING
COL1A1 COL1A1 P3H1 P3H1 COL2A1 COL2A1 TGFBR2 TGFBR2 TGFB1 TGFB1 DCN DCN PPIB PPIB SMAD2 SMAD2 CRTAP CRTAP GAPDH GAPDH COL1A2 COL1A2 F2 F2 PTH PTH
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
COL1A1Collagen type I alpha 1 chain. (1463 aa)
P3H1Prolyl 3-hydroxylase 1. (736 aa)
COL2A1Collagen type II alpha 1 chain. (1259 aa)
TGFBR2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (550 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
DCNDecorin; May affect the rate of fibrils formation. (360 aa)
PPIBPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (216 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
CRTAPCartilage associated protein. (404 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase. (333 aa)
COL1A2Collagen type I alpha 2 chain. (1128 aa)
F2Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (623 aa)
PTHParathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family. (115 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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