36 items (Capra hircus) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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protein homology

Your Input:
	EIF5B	Eukaryotic translation initiation factor 5B. (1220 aa)
	WDR43	WD repeat domain 43. (681 aa)
	LOC108638252	ATP synthase subunit; Mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F1 - containing the extramembraneous catalytic core, and F0 - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F1 is coupled via a rotary mechanism of the central stalk subunits to proto [...] (103 aa)
	EIF4E	Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family. (217 aa)
	MYOD1	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (319 aa)
	LOC102191741	Uncharacterized protein. (152 aa)
	WDR3	WD repeat domain 3. (943 aa)
	ATP5F1B	ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (528 aa)
	SIRT1	Deacetylase sirtuin-type domain-containing protein. (732 aa)
	INS	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (105 aa)
	EIF2S1	Eukaryotic translation initiation factor 2 subunit alpha. (315 aa)
	MCM5	DNA helicase; Belongs to the MCM family. (734 aa)
	EIF4B	RRM domain-containing protein. (615 aa)
	CALCR	Calcitonin receptor; Belongs to the G-protein coupled receptor 2 family. (547 aa)
	CASP3	Caspase 3; Belongs to the peptidase C14A family. (275 aa)
	MYF5	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (260 aa)
	UTP15	UTP15 small subunit processome component. (528 aa)
	YAP1	Yes associated protein 1. (503 aa)
	ATP5MG	ATP synthase membrane subunit g. (103 aa)
	NUMB	NUMB endocytic adaptor protein. (650 aa)
	SDHA	Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (665 aa)
	MTOR	Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2550 aa)
	CDC20	WD_REPEATS_REGION domain-containing protein. (499 aa)
	TIA1	TIA1 cytotoxic granule associated RNA binding protein. (380 aa)
	MYOG	Myogenin. (224 aa)
	EIF4E2	Eukaryotic translation initiation factor 4E family member 2; Belongs to the eukaryotic initiation factor 4E family. (249 aa)
	NUMBL	NUMB like endocytic adaptor protein. (594 aa)
	RPS15	Uncharacterized protein; Belongs to the universal ribosomal protein uS19 family. (144 aa)
	PAX7	Paired box 7. (503 aa)
	AURKA	Aurora kinase A; Belongs to the protein kinase superfamily. (405 aa)
	TP53	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (382 aa)
	CTNNB1	Catenin beta 1. (781 aa)
	MAPK6	Mitogen-activated protein kinase 6. (722 aa)
	DEK	DEK proto-oncogene. (378 aa)
	CREB1	cAMP responsive element binding protein 1. (341 aa)
	ATP5F1D	ATP synthase F1 subunit delta. (168 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATP5F1B	ATP5F1D	ENSCHIP00000007152	ENSCHIP00000033869	ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane.	ATP synthase F1 subunit delta.	0.999
ATP5F1B	ATP5MG	ENSCHIP00000007152	ENSCHIP00000017212	ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane.	ATP synthase membrane subunit g.	0.996
ATP5F1B	AURKA	ENSCHIP00000007152	ENSCHIP00000029258	ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane.	Aurora kinase A; Belongs to the protein kinase superfamily.	0.711
ATP5F1B	CDC20	ENSCHIP00000007152	ENSCHIP00000021954	ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane.	WD_REPEATS_REGION domain-containing protein.	0.432
ATP5F1B	EIF5B	ENSCHIP00000007152	ENSCHIP00000033655	ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane.	Eukaryotic translation initiation factor 5B.	0.455
ATP5F1B	LOC102191741	ENSCHIP00000007152	ENSCHIP00000006057	ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane.	Uncharacterized protein.	0.908
ATP5F1B	LOC108638252	ENSCHIP00000007152	ENSCHIP00000004776	ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane.	ATP synthase subunit; Mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F1 - containing the extramembraneous catalytic core, and F0 - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F1 is coupled via a rotary mechanism of the central stalk subunits to proto [...]	0.996
ATP5F1B	RPS15	ENSCHIP00000007152	ENSCHIP00000027185	ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane.	Uncharacterized protein; Belongs to the universal ribosomal protein uS19 family.	0.452
ATP5F1B	SDHA	ENSCHIP00000007152	ENSCHIP00000018522	ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane.	Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).	0.894
ATP5F1D	ATP5F1B	ENSCHIP00000033869	ENSCHIP00000007152	ATP synthase F1 subunit delta.	ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane.	0.999
ATP5F1D	ATP5MG	ENSCHIP00000033869	ENSCHIP00000017212	ATP synthase F1 subunit delta.	ATP synthase membrane subunit g.	0.999
ATP5F1D	EIF5B	ENSCHIP00000033869	ENSCHIP00000033655	ATP synthase F1 subunit delta.	Eukaryotic translation initiation factor 5B.	0.427
ATP5F1D	LOC102191741	ENSCHIP00000033869	ENSCHIP00000006057	ATP synthase F1 subunit delta.	Uncharacterized protein.	0.927
ATP5F1D	LOC108638252	ENSCHIP00000033869	ENSCHIP00000004776	ATP synthase F1 subunit delta.	ATP synthase subunit; Mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F1 - containing the extramembraneous catalytic core, and F0 - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F1 is coupled via a rotary mechanism of the central stalk subunits to proto [...]	0.999
ATP5F1D	RPS15	ENSCHIP00000033869	ENSCHIP00000027185	ATP synthase F1 subunit delta.	Uncharacterized protein; Belongs to the universal ribosomal protein uS19 family.	0.575
ATP5F1D	SDHA	ENSCHIP00000033869	ENSCHIP00000018522	ATP synthase F1 subunit delta.	Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).	0.872
ATP5F1D	WDR3	ENSCHIP00000033869	ENSCHIP00000006797	ATP synthase F1 subunit delta.	WD repeat domain 3.	0.452
ATP5MG	ATP5F1B	ENSCHIP00000017212	ENSCHIP00000007152	ATP synthase membrane subunit g.	ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane.	0.996
ATP5MG	ATP5F1D	ENSCHIP00000017212	ENSCHIP00000033869	ATP synthase membrane subunit g.	ATP synthase F1 subunit delta.	0.999
ATP5MG	LOC102191741	ENSCHIP00000017212	ENSCHIP00000006057	ATP synthase membrane subunit g.	Uncharacterized protein.	0.767