50 items (Capra hircus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	KRT4	Keratin 4; Belongs to the intermediate filament family. (555 aa)
	COL2A1	Collagen type II alpha 1 chain. (1259 aa)
	CXCL14	C-X-C motif chemokine ligand 14. (99 aa)
	ACKR4	Atypical chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family. (350 aa)
	TBP	Uncharacterized protein. (327 aa)
	HHEX	Hematopoietically expressed homeobox. (271 aa)
	MFSD2A	Major facilitator superfamily domain containing 2A. (524 aa)
	FOXD1	Forkhead box D1. (479 aa)
	COL13A1	Collagen type XIII alpha 1 chain. (440 aa)
	PTGS2	Prostaglandin-endoperoxide synthase 2. (604 aa)
	EPCAM	Epithelial cell adhesion molecule. (314 aa)
	COL14A1	Collagen type XIV alpha 1 chain. (1775 aa)
	GAPDH	Glyceraldehyde-3-phosphate dehydrogenase. (333 aa)
	COL4A1	Collagen type IV alpha 1 chain. (1608 aa)
	CYP11A1	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...] (520 aa)
	FRZB	Frizzled related protein. (325 aa)
	GSN	Gelsolin. (785 aa)
	COL1A1	Collagen type I alpha 1 chain. (1463 aa)
	MYL9	Myosin light chain 9. (172 aa)
	SPARC	Osteonectin. (303 aa)
	KRT7	Keratin 7; Belongs to the intermediate filament family. (466 aa)
	PAX8	Paired box 8. (457 aa)
	ITGA4	Integrin subunit alpha 4; Belongs to the integrin alpha chain family. (1033 aa)
	ALB	Serum albumin. (608 aa)
	FOXF1	Forkhead box F1. (391 aa)
	KRT8	Keratin 8; Belongs to the intermediate filament family. (484 aa)
	SPON2	Spondin 2. (332 aa)
	LHX9	LIM homeobox 9. (397 aa)
	ACTA2	Actin alpha 2, smooth muscle. (377 aa)
	IL11	Interleukin 11. (191 aa)
	REN	Renin; Belongs to the peptidase A1 family. (403 aa)
	TCF21	Transcription factor 21. (179 aa)
	KRT14	Keratin 14; Belongs to the intermediate filament family. (514 aa)
	TAGLN	Transgelin; Belongs to the calponin family. (201 aa)
	WNT7B	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (416 aa)
	FOXA2	Forkhead box A2. (467 aa)
	CCL2	C-C motif chemokine. (98 aa)
	NUBP2	Cytosolic Fe-S cluster assembly factor NUBP2; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily. (273 aa)
	OLFML1	Olfactomedin like 1. (402 aa)
	MFAP4	Microfibril associated protein 4. (255 aa)
	RCC2	Regulator of chromosome condensation 2. (520 aa)
	COL1A2	Collagen type I alpha 2 chain. (1128 aa)
	TNFSF18	TNF superfamily member 18. (194 aa)
	TGFB1	Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
	PI16	Peptidase inhibitor 16; Belongs to the CRISP family. (464 aa)
	TBX20	T-box transcription factor 20. (449 aa)
	SERPINB5	Serpin family B member 5; Belongs to the serpin family. (375 aa)
	EHF	ETS homologous factor. (311 aa)
	LOC102182127	Clusterin; Functions as extracellular chaperone that prevents aggregation of non native proteins. Prevents stress-induced aggregation of blood plasma proteins. (439 aa)
	BMP7	Bone morphogenetic protein 7. (431 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACKR4	CCL2	ENSCHIP00000003939	ENSCHIP00000027804	Atypical chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family.	C-C motif chemokine.	0.541
ACKR4	PI16	ENSCHIP00000003939	ENSCHIP00000008802	Atypical chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family.	Peptidase inhibitor 16; Belongs to the CRISP family.	0.520
ACKR4	TNFSF18	ENSCHIP00000003939	ENSCHIP00000008887	Atypical chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family.	TNF superfamily member 18.	0.655
ACTA2	ALB	ENSCHIP00000018506	ENSCHIP00000020234	Actin alpha 2, smooth muscle.	Serum albumin.	0.476
ACTA2	COL1A1	ENSCHIP00000018506	ENSCHIP00000023918	Actin alpha 2, smooth muscle.	Collagen type I alpha 1 chain.	0.803
ACTA2	COL1A2	ENSCHIP00000018506	ENSCHIP00000031191	Actin alpha 2, smooth muscle.	Collagen type I alpha 2 chain.	0.654
ACTA2	COL4A1	ENSCHIP00000018506	ENSCHIP00000025370	Actin alpha 2, smooth muscle.	Collagen type IV alpha 1 chain.	0.505
ACTA2	EPCAM	ENSCHIP00000018506	ENSCHIP00000026828	Actin alpha 2, smooth muscle.	Epithelial cell adhesion molecule.	0.477
ACTA2	GAPDH	ENSCHIP00000018506	ENSCHIP00000025974	Actin alpha 2, smooth muscle.	Glyceraldehyde-3-phosphate dehydrogenase.	0.669
ACTA2	GSN	ENSCHIP00000018506	ENSCHIP00000023939	Actin alpha 2, smooth muscle.	Gelsolin.	0.465
ACTA2	KRT14	ENSCHIP00000018506	ENSCHIP00000013319	Actin alpha 2, smooth muscle.	Keratin 14; Belongs to the intermediate filament family.	0.507
ACTA2	KRT8	ENSCHIP00000018506	ENSCHIP00000019928	Actin alpha 2, smooth muscle.	Keratin 8; Belongs to the intermediate filament family.	0.480
ACTA2	MYL9	ENSCHIP00000018506	ENSCHIP00000023463	Actin alpha 2, smooth muscle.	Myosin light chain 9.	0.983
ACTA2	PI16	ENSCHIP00000018506	ENSCHIP00000008802	Actin alpha 2, smooth muscle.	Peptidase inhibitor 16; Belongs to the CRISP family.	0.472
ACTA2	TAGLN	ENSCHIP00000018506	ENSCHIP00000013286	Actin alpha 2, smooth muscle.	Transgelin; Belongs to the calponin family.	0.933
ACTA2	TBP	ENSCHIP00000018506	ENSCHIP00000003904	Actin alpha 2, smooth muscle.	Uncharacterized protein.	0.563
ACTA2	TCF21	ENSCHIP00000018506	ENSCHIP00000014722	Actin alpha 2, smooth muscle.	Transcription factor 21.	0.484
ACTA2	TGFB1	ENSCHIP00000018506	ENSCHIP00000008885	Actin alpha 2, smooth muscle.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.546
ALB	ACTA2	ENSCHIP00000020234	ENSCHIP00000018506	Serum albumin.	Actin alpha 2, smooth muscle.	0.476
ALB	BMP7	ENSCHIP00000020234	ENSCHIP00000006043	Serum albumin.	Bone morphogenetic protein 7.	0.611