42 items (Capra hircus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	KDM6A	Lysine demethylase 6A. (1386 aa)
	LOC102191748	Histone domain-containing protein. (136 aa)
	LOC102185882	Histone H3; Belongs to the histone H3 family. (136 aa)
	LOC108633554	Histone domain-containing protein. (136 aa)
	LOC102182848	Histone H3; Belongs to the histone H3 family. (136 aa)
	LOC108633784	Big gastrin; Gastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes. It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine; Belongs to the gastrin/cholecystokinin family. (104 aa)
	EZH2	Enhancer of zeste 2 polycomb repressive complex 2 subunit. (746 aa)
	LOC108636012	Histone H3; Belongs to the histone H3 family. (136 aa)
	H3-4	Histone H3; Belongs to the histone H3 family. (136 aa)
	LOC108634231	Histone H3; Belongs to the histone H3 family. (136 aa)
	NOG	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
	NCOR2	Nuclear receptor corepressor 2. (2479 aa)
	LOC102180554	Histone H3; Belongs to the histone H3 family. (136 aa)
	LOC106503499	Histone H3; Belongs to the histone H3 family. (136 aa)
	LOC108633916	Histone H3; Belongs to the histone H3 family. (136 aa)
	LOC102171353	Histone H3; Belongs to the histone H3 family. (136 aa)
	LOC102169981	Histone domain-containing protein. (136 aa)
	NFIB	Nuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. (570 aa)
	GAST	Gastrin. (104 aa)
	KMT2C	Lysine methyltransferase 2C. (4894 aa)
	FGF10	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (213 aa)
	NCAM1	Neural cell adhesion molecule 1. (1007 aa)
	ASCL1	Achaete-scute family bHLH transcription factor 1. (219 aa)
	ACTB	Uncharacterized protein. (375 aa)
	NEUROD1	Neurogenic differentiation factor. (356 aa)
	MEIS2	Meis homeobox 2. (470 aa)
	HOXB3	Homeobox B3. (426 aa)
	DNMT3A	DNA methyltransferase 3 alpha; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (915 aa)
	KMT2D	Lysine methyltransferase 2D. (5491 aa)
	CHGA	Chromogranin A. (534 aa)
	WNT3A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (363 aa)
	HOXB7	Homeobox B7. (217 aa)
	KDM5B	Lysine demethylase 5B. (1539 aa)
	NOTCH1	Notch receptor 1. (2508 aa)
	LOC102189503	Histone H3; Belongs to the histone H3 family. (136 aa)
	HOXB9	Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (250 aa)
	HOXB5	Homeobox B5. (269 aa)
	MMUT	Methylmalonyl-CoA mutase. (771 aa)
	FOXA1	Forkhead box A1. (468 aa)
	RSPO1	Ovarian R-spondin member 1. (262 aa)
	HOXB4	Homeobox B4. (251 aa)
	HOXB2	Homeobox B2. (354 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTB	CHGA	ENSCHIP00000011080	ENSCHIP00000014620	Uncharacterized protein.	Chromogranin A.	0.431
ACTB	DNMT3A	ENSCHIP00000011080	ENSCHIP00000012630	Uncharacterized protein.	DNA methyltransferase 3 alpha; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	0.729
ACTB	EZH2	ENSCHIP00000011080	ENSCHIP00000003420	Uncharacterized protein.	Enhancer of zeste 2 polycomb repressive complex 2 subunit.	0.696
ACTB	FGF10	ENSCHIP00000011080	ENSCHIP00000010028	Uncharacterized protein.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.589
ACTB	FOXA1	ENSCHIP00000011080	ENSCHIP00000027706	Uncharacterized protein.	Forkhead box A1.	0.421
ACTB	H3-4	ENSCHIP00000011080	ENSCHIP00000004038	Uncharacterized protein.	Histone H3; Belongs to the histone H3 family.	0.904
ACTB	KDM6A	ENSCHIP00000011080	ENSCHIP00000032197	Uncharacterized protein.	Lysine demethylase 6A.	0.449
ACTB	LOC102169981	ENSCHIP00000011080	ENSCHIP00000008812	Uncharacterized protein.	Histone domain-containing protein.	0.901
ACTB	LOC102171353	ENSCHIP00000011080	ENSCHIP00000008371	Uncharacterized protein.	Histone H3; Belongs to the histone H3 family.	0.904
ACTB	LOC102180554	ENSCHIP00000011080	ENSCHIP00000006161	Uncharacterized protein.	Histone H3; Belongs to the histone H3 family.	0.920
ACTB	LOC102182848	ENSCHIP00000011080	ENSCHIP00000002894	Uncharacterized protein.	Histone H3; Belongs to the histone H3 family.	0.904
ACTB	LOC102185882	ENSCHIP00000011080	ENSCHIP00000001379	Uncharacterized protein.	Histone H3; Belongs to the histone H3 family.	0.920
ACTB	LOC102189503	ENSCHIP00000011080	ENSCHIP00000024908	Uncharacterized protein.	Histone H3; Belongs to the histone H3 family.	0.920
ACTB	LOC102191748	ENSCHIP00000011080	ENSCHIP00000000846	Uncharacterized protein.	Histone domain-containing protein.	0.904
ACTB	LOC106503499	ENSCHIP00000011080	ENSCHIP00000006566	Uncharacterized protein.	Histone H3; Belongs to the histone H3 family.	0.920
ACTB	LOC108633554	ENSCHIP00000011080	ENSCHIP00000001940	Uncharacterized protein.	Histone domain-containing protein.	0.904
ACTB	LOC108633916	ENSCHIP00000011080	ENSCHIP00000006619	Uncharacterized protein.	Histone H3; Belongs to the histone H3 family.	0.904
ACTB	LOC108634231	ENSCHIP00000011080	ENSCHIP00000004083	Uncharacterized protein.	Histone H3; Belongs to the histone H3 family.	0.904
ACTB	LOC108636012	ENSCHIP00000011080	ENSCHIP00000003430	Uncharacterized protein.	Histone H3; Belongs to the histone H3 family.	0.920
ACTB	MMUT	ENSCHIP00000011080	ENSCHIP00000027222	Uncharacterized protein.	Methylmalonyl-CoA mutase.	0.806