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TNNI2 TNNI2 CALML4 CALML4 TNNT3 TNNT3 ARPC2 ARPC2 TPM4 TPM4 CALML5 CALML5 TTR TTR MYH8 MYH8 LOC102168811 LOC102168811 FLNA FLNA COL5A2 COL5A2 APOA4 APOA4 ACTB ACTB MYL3 MYL3 KRT77 KRT77 HDDC2 HDDC2 FGB FGB ETFA ETFA FLNB FLNB MYL1 MYL1 TTN TTN TPM3 TPM3 ACTA2 ACTA2 MYH10 MYH10 KRT8 KRT8 FKBP3 FKBP3 AEBP1 AEBP1 CNN1 CNN1 MYL2 MYL2 TPM1 TPM1 EFEMP1 EFEMP1 AHSG AHSG FLNC FLNC COL1A1 COL1A1 MYH7 MYH7 CALM1 CALM1 COL4A1 COL4A1 ARPC3 ARPC3 MDH2 MDH2 PVALB PVALB KRT10 KRT10 YWHAG YWHAG COL1A2 COL1A2 COL5A3 COL5A3 COL4A2 COL4A2 KRT1 KRT1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TNNI2Troponin I2, fast skeletal type. (170 aa)
CALML4Calmodulin like 4. (153 aa)
TNNT3Troponin T3, fast skeletal type. (258 aa)
ARPC2Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (303 aa)
TPM4Tropomyosin 4; Belongs to the tropomyosin family. (284 aa)
CALML5Calmodulin like 5. (149 aa)
TTRTransthyretin; Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain. (147 aa)
MYH8Myosin heavy chain 8; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1937 aa)
LOC102168811Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (289 aa)
FLNAFilamin A. (2647 aa)
COL5A2Collagen type V alpha 2 chain. (1252 aa)
APOA4Apolipoprotein A4. (380 aa)
ACTBUncharacterized protein. (375 aa)
MYL3Myosin light chain 3. (194 aa)
KRT77Keratin 77; Belongs to the intermediate filament family. (602 aa)
HDDC2HD domain containing 2. (205 aa)
FGBFibrinogen beta chain; Cleaved by the protease thrombin to yield monomers which, together with fibrinogen alpha (FGA) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re- epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However subsequent studies have shown that it i [...] (494 aa)
ETFAElectron transfer flavoprotein subunit alpha. (339 aa)
FLNBFilamin B. (2602 aa)
MYL1Myosin light chain 1. (174 aa)
TTNUncharacterized protein. (2149 aa)
TPM3Tropomyosin 3; Belongs to the tropomyosin family. (290 aa)
ACTA2Actin alpha 2, smooth muscle. (377 aa)
MYH10Myosin heavy chain 10; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1975 aa)
KRT8Keratin 8; Belongs to the intermediate filament family. (484 aa)
FKBP3Peptidylprolyl isomerase. (224 aa)
AEBP1AE binding protein 1. (1161 aa)
CNN1Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. (297 aa)
MYL2Myosin light chain 2. (178 aa)
TPM1Uncharacterized protein; Belongs to the tropomyosin family. (284 aa)
EFEMP1EGF containing fibulin extracellular matrix protein 1. (498 aa)
AHSGAlpha 2-HS glycoprotein. (359 aa)
FLNCFilamin C. (2720 aa)
COL1A1Collagen type I alpha 1 chain. (1463 aa)
MYH7Myosin heavy chain 7; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1955 aa)
CALM1Calmodulin 2; Belongs to the calmodulin family. (149 aa)
COL4A1Collagen type IV alpha 1 chain. (1608 aa)
ARPC3Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (194 aa)
MDH2Malate dehydrogenase. (338 aa)
PVALBParvalbumin; Belongs to the parvalbumin family. (111 aa)
KRT10Keratin 10; Belongs to the intermediate filament family. (564 aa)
YWHAGTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma; Belongs to the 14-3-3 family. (247 aa)
COL1A2Collagen type I alpha 2 chain. (1128 aa)
COL5A3Collagen type V alpha 3 chain. (1455 aa)
COL4A2Collagen type IV alpha 2 chain. (1607 aa)
KRT1Keratin 1; Belongs to the intermediate filament family. (614 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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