27 items (Capra hircus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RNASEH1	Ribonuclease H1; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (285 aa)
	LOC108633295	ZZ-type domain-containing protein. (323 aa)
	FBL	Fibrillarin. (333 aa)
	LOC106502806	Uncharacterized protein. (616 aa)
	TIA1	TIA1 cytotoxic granule associated RNA binding protein. (380 aa)
	PSPC1	Paraspeckle component 1. (520 aa)
	BCL2	BH4_2 domain-containing protein. (229 aa)
	E2F1	E2F transcription factor 1. (441 aa)
	SOD1	Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the Cu-Zn superoxide dismutase family. (154 aa)
	NCL	Uncharacterized protein. (667 aa)
	NONO	Non-POU domain containing octamer binding. (470 aa)
	LMNB1	Lamin B1; Belongs to the intermediate filament family. (586 aa)
	ACTB	Uncharacterized protein. (375 aa)
	LOC102181016	Gp_dh_N domain-containing protein; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (318 aa)
	CCND1	Cyclin D1; Belongs to the cyclin family. (295 aa)
	CASP3	Caspase 3; Belongs to the peptidase C14A family. (275 aa)
	RRM2	Ribonucleotide reductase regulatory subunit M2. (389 aa)
	GAPDHS	Glyceraldehyde-3-phosphate dehydrogenase. (385 aa)
	LOC102176799	Glyceraldehyde-3-phosphate dehydrogenase. (333 aa)
	TBP	Uncharacterized protein. (327 aa)
	FUS	FUS RNA binding protein. (522 aa)
	SUPT4H1	Transcription elongation factor SPT4; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II; Belongs to the SPT4 family. (117 aa)
	TUBB	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (444 aa)
	HNRNPA1	Uncharacterized protein. (320 aa)
	TP53	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (382 aa)
	SFPQ	Splicing factor proline and glutamine rich. (711 aa)
	GAPDH	Glyceraldehyde-3-phosphate dehydrogenase. (333 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTB	BCL2	ENSCHIP00000011080	ENSCHIP00000015831	Uncharacterized protein.	BH4_2 domain-containing protein.	0.940
ACTB	CASP3	ENSCHIP00000011080	ENSCHIP00000011490	Uncharacterized protein.	Caspase 3; Belongs to the peptidase C14A family.	0.996
ACTB	CCND1	ENSCHIP00000011080	ENSCHIP00000006815	Uncharacterized protein.	Cyclin D1; Belongs to the cyclin family.	0.890
ACTB	E2F1	ENSCHIP00000011080	ENSCHIP00000014803	Uncharacterized protein.	E2F transcription factor 1.	0.716
ACTB	FBL	ENSCHIP00000011080	ENSCHIP00000024358	Uncharacterized protein.	Fibrillarin.	0.517
ACTB	FUS	ENSCHIP00000011080	ENSCHIP00000002026	Uncharacterized protein.	FUS RNA binding protein.	0.558
ACTB	GAPDH	ENSCHIP00000011080	ENSCHIP00000025974	Uncharacterized protein.	Glyceraldehyde-3-phosphate dehydrogenase.	0.979
ACTB	GAPDHS	ENSCHIP00000011080	ENSCHIP00000005676	Uncharacterized protein.	Glyceraldehyde-3-phosphate dehydrogenase.	0.911
ACTB	HNRNPA1	ENSCHIP00000011080	ENSCHIP00000030443	Uncharacterized protein.	Uncharacterized protein.	0.567
ACTB	LMNB1	ENSCHIP00000011080	ENSCHIP00000011489	Uncharacterized protein.	Lamin B1; Belongs to the intermediate filament family.	0.904
ACTB	LOC102176799	ENSCHIP00000011080	ENSCHIP00000004827	Uncharacterized protein.	Glyceraldehyde-3-phosphate dehydrogenase.	0.937
ACTB	LOC102181016	ENSCHIP00000011080	ENSCHIP00000010405	Uncharacterized protein.	Gp_dh_N domain-containing protein; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.	0.917
ACTB	LOC106502806	ENSCHIP00000011080	ENSCHIP00000023515	Uncharacterized protein.	Uncharacterized protein.	0.608
ACTB	LOC108633295	ENSCHIP00000011080	ENSCHIP00000025087	Uncharacterized protein.	ZZ-type domain-containing protein.	0.499
ACTB	NCL	ENSCHIP00000011080	ENSCHIP00000007425	Uncharacterized protein.	Uncharacterized protein.	0.608
ACTB	NONO	ENSCHIP00000011080	ENSCHIP00000000521	Uncharacterized protein.	Non-POU domain containing octamer binding.	0.402
ACTB	RRM2	ENSCHIP00000011080	ENSCHIP00000005712	Uncharacterized protein.	Ribonucleotide reductase regulatory subunit M2.	0.424
ACTB	SOD1	ENSCHIP00000011080	ENSCHIP00000012974	Uncharacterized protein.	Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the Cu-Zn superoxide dismutase family.	0.804
ACTB	TBP	ENSCHIP00000011080	ENSCHIP00000003904	Uncharacterized protein.	Uncharacterized protein.	0.876
ACTB	TIA1	ENSCHIP00000011080	ENSCHIP00000022609	Uncharacterized protein.	TIA1 cytotoxic granule associated RNA binding protein.	0.447