STRINGSTRING
LOC102184245 LOC102184245 KRT5 KRT5 SERPINH1 SERPINH1 HPX HPX ERO1A ERO1A CTSD CTSD ANXA2 ANXA2 ENSCHIP00000003120 ENSCHIP00000003120 PPA2 PPA2 EEF1A1 EEF1A1 LOC102182127 LOC102182127 KRT17 KRT17 INS INS EEF1D EEF1D ARHGDIB ARHGDIB AKR1B1 AKR1B1 KEAP1 KEAP1 CLUL1 CLUL1 MSN MSN MYC MYC MYL3 MYL3 RHOA RHOA EEF2 EEF2 LITAF LITAF LARP1 LARP1 SCIN SCIN LGALS1 LGALS1 FGB FGB PIK3C3 PIK3C3 HIF1A HIF1A PKM PKM PPA1 PPA1 KDM8 KDM8 ALDH3B2 ALDH3B2 LTA4H LTA4H EZR EZR SNX6 SNX6 HSP90AB1 HSP90AB1 TUBA1B TUBA1B DPYSL3 DPYSL3 SERPINB1 SERPINB1 KRT8 KRT8 ALB ALB RUVBL1 RUVBL1 LOC102168959 LOC102168959 RDX RDX LEP LEP PSMA1 PSMA1 LOC102183600 LOC102183600 TUBB4A TUBB4A PDIA4 PDIA4 VIM VIM EGFR EGFR EHD1 EHD1 GSN GSN TUBB2B TUBB2B TF TF LOC102185401 LOC102185401 STK11 STK11 PARK7 PARK7 TUBB4B TUBB4B HSP90AA1 HSP90AA1 EEF1G EEF1G PRDX4 PRDX4 CAPZA1 CAPZA1 CLPP CLPP LARP1B LARP1B MAPRE1 MAPRE1 ALDH2 ALDH2 CALR CALR WARS1 WARS1 LOC106502860 LOC106502860 IL15 IL15 PDIA3 PDIA3 LOC102168680 LOC102168680 KRT10 KRT10 TUBB6 TUBB6 ALDH3A1 ALDH3A1 S100A4 S100A4 TUBB2A TUBB2A TUBB TUBB TUBB1 TUBB1 CCT2 CCT2 NFE2L2 NFE2L2 ALDH3B1 ALDH3B1 LOC102176354 LOC102176354 LOC102181148 LOC102181148 AHCY AHCY CS CS ALDH3A2 ALDH3A2
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
LOC102184245Alpha-carbonic anhydrase domain-containing protein; Belongs to the alpha-carbonic anhydrase family. (261 aa)
KRT5Keratin 5; Belongs to the intermediate filament family. (561 aa)
SERPINH1Serpin family H member 1; Belongs to the serpin family. (418 aa)
HPXHemopexin; Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation. (459 aa)
ERO1AEndoplasmic reticulum oxidoreductase 1 alpha. (460 aa)
CTSDPeptidase A1 domain-containing protein; Belongs to the peptidase A1 family. (412 aa)
ANXA2Annexin. (339 aa)
ENSCHIP00000003120Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (462 aa)
PPA2Uncharacterized protein. (342 aa)
EEF1A1Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (462 aa)
LOC102182127Clusterin; Functions as extracellular chaperone that prevents aggregation of non native proteins. Prevents stress-induced aggregation of blood plasma proteins. (439 aa)
KRT17Keratin 17; Belongs to the intermediate filament family. (448 aa)
INSInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (105 aa)
EEF1DUncharacterized protein; Belongs to the EF-1-beta/EF-1-delta family. (280 aa)
ARHGDIBRho GDP dissociation inhibitor beta. (200 aa)
AKR1B1Aldo_ket_red domain-containing protein. (316 aa)
KEAP1Kelch like ECH associated protein 1. (624 aa)
CLUL1Clusterin; Belongs to the clusterin family. (464 aa)
MSNMoesin. (666 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (439 aa)
MYL3Myosin light chain 3. (194 aa)
RHOARas-like protein family member A. (193 aa)
EEF2Tr-type G domain-containing protein. (858 aa)
LITAFLipopolysaccharide induced TNF factor. (161 aa)
LARP1La ribonucleoprotein domain family member 1. (1144 aa)
SCINScinderin. (715 aa)
LGALS1Galectin-1; Lectin that binds beta-galactoside and a wide array of complex carbohydrates. Plays a role in regulating apoptosis, cell proliferation and cell differentiation. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase. Strong inducer of T-cell apoptosis. Has hemaglutinating activity towards human erythrocytes. (136 aa)
FGBFibrinogen beta chain; Cleaved by the protease thrombin to yield monomers which, together with fibrinogen alpha (FGA) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re- epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However subsequent studies have shown that it i [...] (494 aa)
PIK3C3Phosphatidylinositol 3-kinase catalytic subunit type 3. (900 aa)
HIF1AUncharacterized protein. (823 aa)
PKMPyruvate kinase; Belongs to the pyruvate kinase family. (531 aa)
PPA1Pyrophosphatase (inorganic) 1. (289 aa)
KDM8Lysine demethylase 8. (406 aa)
ALDH3B2Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (466 aa)
LTA4HLeukotriene A(4) hydrolase; Belongs to the peptidase M1 family. (611 aa)
EZREzrin. (581 aa)
SNX6Sorting nexin; Involved in several stages of intracellular trafficking. (406 aa)
HSP90AB1Heat shock protein 90 alpha family class B member 1. (724 aa)
TUBA1BTubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (456 aa)
DPYSL3Dihydropyrimidinase like 3. (684 aa)
SERPINB1Serpin family B member 1; Belongs to the serpin family. (390 aa)
KRT8Keratin 8; Belongs to the intermediate filament family. (484 aa)
ALBSerum albumin. (608 aa)
RUVBL1RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa)
LOC102168959Hemoglobin subunit alpha-2; Involved in oxygen transport from the lung to the various peripheral tissues. (142 aa)
RDXRadixin. (602 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways (By similarity). In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, inc [...] (192 aa)
PSMA1Proteasome subunit alpha type. (263 aa)
LOC102183600Clusterin; Belongs to the clusterin family. (463 aa)
TUBB4ATubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (444 aa)
PDIA4Protein disulfide-isomerase A4. (644 aa)
VIMVimentin; Belongs to the intermediate filament family. (471 aa)
EGFRReceptor protein-tyrosine kinase. (1208 aa)
EHD1Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (534 aa)
GSNGelsolin. (785 aa)
TUBB2BTubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (445 aa)
TFTransferrin; Belongs to the transferrin family. (698 aa)
LOC102185401SERPIN domain-containing protein; Belongs to the serpin family. (441 aa)
STK11Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (442 aa)
PARK7Parkinsonism associated deglycase. (189 aa)
TUBB4BTubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (446 aa)
HSP90AA1Heat shock protein 90 alpha family class A member 1. (733 aa)
EEF1GUncharacterized protein. (440 aa)
PRDX4Peroxiredoxin 4. (275 aa)
CAPZA1F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (287 aa)
CLPPATP-dependent Clp protease proteolytic subunit. (272 aa)
LARP1BLa ribonucleoprotein domain family member 1B. (930 aa)
MAPRE1Microtubule associated protein RP/EB family member 1. (268 aa)
ALDH2Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (524 aa)
CALRCalreticulin. (417 aa)
WARS1Tryptophanyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (482 aa)
LOC106502860Alpha-carbonic anhydrase domain-containing protein; Belongs to the alpha-carbonic anhydrase family. (261 aa)
IL15Interleukin; Belongs to the IL-15/IL-21 family. (161 aa)
PDIA3Protein disulfide-isomerase. (505 aa)
LOC102168680Hemoglobin subunit alpha-1; Involved in oxygen transport from the lung to the various peripheral tissues. (142 aa)
KRT10Keratin 10; Belongs to the intermediate filament family. (564 aa)
TUBB6Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (446 aa)
ALDH3A1Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (453 aa)
S100A4Protein S100; Belongs to the S-100 family. (101 aa)
TUBB2ATubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (445 aa)
TUBBTubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (444 aa)
TUBB1Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
CCT2Chaperonin containing TCP1 subunit 2. (535 aa)
NFE2L2Nuclear factor erythroid 2-related factor 2. (616 aa)
ALDH3B1Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (468 aa)
LOC102176354Uncharacterized protein; Belongs to the peptidase S1 family. (401 aa)
LOC102181148Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (450 aa)
AHCYAdenosylhomocysteinase; Belongs to the adenosylhomocysteinase family. (432 aa)
CSCitrate synthase; Belongs to the citrate synthase family. (454 aa)
ALDH3A2Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (500 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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