STRINGSTRING
BMP4 BMP4 FGF3 FGF3 FGF4 FGF4 TGFB1 TGFB1 FGF10 FGF10 CASP3 CASP3 SMAD3 SMAD3 BAMBI BAMBI ALB ALB SMAD7 SMAD7 AXIN2 AXIN2 MDK MDK WNT11 WNT11 ISL1 ISL1 SHH SHH LEF1 LEF1 CTNNB1 CTNNB1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BMP4Bone morphogenetic protein 4. (409 aa)
FGF3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (232 aa)
FGF4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (213 aa)
CASP3Caspase 3; Belongs to the peptidase C14A family. (275 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
BAMBIBMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. (260 aa)
ALBSerum albumin. (608 aa)
SMAD7Mothers against decapentaplegic homolog. (427 aa)
AXIN2Axin 2. (844 aa)
MDKMidkine. (143 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
ISL1ISL LIM homeobox 1. (349 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (443 aa)
LEF1HMG box domain-containing protein. (430 aa)
CTNNB1Catenin beta 1. (781 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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