(26 nodes) (2022) Molecular cloning, characterization, and functional analysis of the uncharacterized C11orf96 gene. network (Capra hircus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MYCN	MYCN proto-oncogene, bHLH transcription factor. (554 aa)
	ALB	Serum albumin. (608 aa)
	RPS5	Ribosomal protein S5; Belongs to the universal ribosomal protein uS7 family. (204 aa)
	LDLR	Low density lipoprotein receptor. (787 aa)
	KCNQ1	Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (670 aa)
	VAPA	VAMP associated protein A. (294 aa)
	TMCO3	Transmembrane and coiled-coil domains 3. (677 aa)
	MX1	MX dynamin like GTPase 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (654 aa)
	TMEM117	Transmembrane protein 117. (524 aa)
	EIF4E	Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family. (217 aa)
	CD4	CD4 molecule. (455 aa)
	RPS6	40S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (255 aa)
	PHLDA2	Pleckstrin homology like domain family A member 2. (128 aa)
	CDKN1C	Cyclin dependent kinase inhibitor 1C. (254 aa)
	ACTB	Uncharacterized protein. (375 aa)
	TM4SF19	Uncharacterized protein. (202 aa)
	ACE2	Angiotensin-converting enzyme. (804 aa)
	GAPDH	Glyceraldehyde-3-phosphate dehydrogenase. (333 aa)
	MARCHF4	Membrane associated ring-CH-type finger 4. (409 aa)
	TMEM106C	Transmembrane protein 106C. (249 aa)
	VAPB	VAMP associated protein B and C. (243 aa)
	PLEK2	Pleckstrin 2. (354 aa)
	ISG15	Interferon-stimulated protein 17/ubiquitin cross-reactive protein. (157 aa)
	SLC22A18	Solute carrier family 22 member 18. (432 aa)
	PLEK	Pleckstrin. (356 aa)
	ZNF331	Zinc finger protein 331. (486 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACE2	ACTB	ENSCHIP00000016062	ENSCHIP00000011080	Angiotensin-converting enzyme.	Uncharacterized protein.	0.720
ACE2	ALB	ENSCHIP00000016062	ENSCHIP00000020234	Angiotensin-converting enzyme.	Serum albumin.	0.884
ACE2	CD4	ENSCHIP00000016062	ENSCHIP00000006662	Angiotensin-converting enzyme.	CD4 molecule.	0.844
ACE2	GAPDH	ENSCHIP00000016062	ENSCHIP00000025974	Angiotensin-converting enzyme.	Glyceraldehyde-3-phosphate dehydrogenase.	0.733
ACE2	ISG15	ENSCHIP00000016062	ENSCHIP00000017154	Angiotensin-converting enzyme.	Interferon-stimulated protein 17/ubiquitin cross-reactive protein.	0.430
ACTB	ACE2	ENSCHIP00000011080	ENSCHIP00000016062	Uncharacterized protein.	Angiotensin-converting enzyme.	0.720
ACTB	ALB	ENSCHIP00000011080	ENSCHIP00000020234	Uncharacterized protein.	Serum albumin.	0.961
ACTB	CD4	ENSCHIP00000011080	ENSCHIP00000006662	Uncharacterized protein.	CD4 molecule.	0.883
ACTB	EIF4E	ENSCHIP00000011080	ENSCHIP00000005408	Uncharacterized protein.	Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family.	0.712
ACTB	GAPDH	ENSCHIP00000011080	ENSCHIP00000025974	Uncharacterized protein.	Glyceraldehyde-3-phosphate dehydrogenase.	0.979
ACTB	ISG15	ENSCHIP00000011080	ENSCHIP00000017154	Uncharacterized protein.	Interferon-stimulated protein 17/ubiquitin cross-reactive protein.	0.722
ACTB	MX1	ENSCHIP00000011080	ENSCHIP00000001236	Uncharacterized protein.	MX dynamin like GTPase 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.720
ACTB	MYCN	ENSCHIP00000011080	ENSCHIP00000018462	Uncharacterized protein.	MYCN proto-oncogene, bHLH transcription factor.	0.589
ACTB	PLEK	ENSCHIP00000011080	ENSCHIP00000018122	Uncharacterized protein.	Pleckstrin.	0.599
ACTB	PLEK2	ENSCHIP00000011080	ENSCHIP00000027528	Uncharacterized protein.	Pleckstrin 2.	0.578
ACTB	RPS6	ENSCHIP00000011080	ENSCHIP00000006669	Uncharacterized protein.	40S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family.	0.747
ALB	ACE2	ENSCHIP00000020234	ENSCHIP00000016062	Serum albumin.	Angiotensin-converting enzyme.	0.884
ALB	ACTB	ENSCHIP00000020234	ENSCHIP00000011080	Serum albumin.	Uncharacterized protein.	0.961
ALB	CD4	ENSCHIP00000020234	ENSCHIP00000006662	Serum albumin.	CD4 molecule.	0.977
ALB	EIF4E	ENSCHIP00000020234	ENSCHIP00000005408	Serum albumin.	Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family.	0.530