STRINGSTRING
LRAT LRAT ALDH3A2 ALDH3A2 RXRG RXRG ALDH3B1 ALDH3B1 ALDH3A1 ALDH3A1 CCN2 CCN2 TIMP2 TIMP2 SREBF1 SREBF1 LTBP1 LTBP1 RXRA RXRA RARG RARG PAX6 PAX6 ALDH8A1 ALDH8A1 TGFB2 TGFB2 MMP3 MMP3 GAPDH GAPDH IL17A IL17A COL4A1 COL4A1 APOE APOE LOXL1 LOXL1 FBN1 FBN1 COL1A1 COL1A1 CYP26C1 CYP26C1 RBP1 RBP1 ALDH1A3 ALDH1A3 SMAD2 SMAD2 LEP LEP CRABP1 CRABP1 ALB ALB MFAP2 MFAP2 FBLN1 FBLN1 ALDH1A1 ALDH1A1 FBLN5 FBLN5 CYP26B1 CYP26B1 CYP26A1 CYP26A1 ALDH3B2 ALDH3B2 RDH10 RDH10 WNT5A WNT5A PXDN PXDN PPARG PPARG HPRT1 HPRT1 RDH5 RDH5 PPARD PPARD ACTB ACTB IL6 IL6 RARB RARB RBP3 RBP3 TGFBR2 TGFBR2 TTR TTR CRABP2 CRABP2 LTBP2 LTBP2 ENSCHIP00000003120 ENSCHIP00000003120 RORC RORC CD38 CD38 HSD17B2 HSD17B2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LRATLecithin retinol acyltransferase. (230 aa)
ALDH3A2Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (500 aa)
RXRGRetinoid X receptor gamma. (539 aa)
ALDH3B1Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (468 aa)
ALDH3A1Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (453 aa)
CCN2Cellular communication network factor 2. (349 aa)
TIMP2TIMP metallopeptidase inhibitor 2. (220 aa)
SREBF1Uncharacterized protein. (68 aa)
LTBP1Latent transforming growth factor beta binding protein 1. (1491 aa)
RXRANR LBD domain-containing protein. (106 aa)
RARGRetinoic acid receptor gamma. (458 aa)
PAX6Paired box 6. (486 aa)
ALDH8A1Aldehyde dehydrogenase 8 family member A1; Belongs to the aldehyde dehydrogenase family. (487 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
MMP3Matrix metallopeptidase 3. (477 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase. (333 aa)
IL17AInterleukin-17A. (153 aa)
COL4A1Collagen type IV alpha 1 chain. (1608 aa)
APOEApolipoprotein E. (326 aa)
LOXL1Lysyl oxidase like 1. (592 aa)
FBN1Fibrillin 1. (2860 aa)
COL1A1Collagen type I alpha 1 chain. (1463 aa)
CYP26C1Cytochrome P450 family 26 subfamily C member 1; Belongs to the cytochrome P450 family. (523 aa)
RBP1Cellular retinol binding protein 1; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (135 aa)
ALDH1A3Aldehyde dehydrogenase 1 family member A3; Belongs to the aldehyde dehydrogenase family. (512 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways (By similarity). In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, inc [...] (192 aa)
CRABP1Cellular retinoic acid binding protein 1; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (137 aa)
ALBSerum albumin. (608 aa)
MFAP2Microfibril associated protein 2. (185 aa)
FBLN1Fibulin-1; Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes. (713 aa)
ALDH1A1Aldehyde dehydrogenase 1 family member A1; Belongs to the aldehyde dehydrogenase family. (501 aa)
FBLN5Fibulin 5. (448 aa)
CYP26B1Cytochrome P450 family 26 subfamily B member 1; Belongs to the cytochrome P450 family. (512 aa)
CYP26A1Cytochrome P450 family 26 subfamily A member 1; Belongs to the cytochrome P450 family. (497 aa)
ALDH3B2Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (466 aa)
RDH10Retinol dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (341 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (381 aa)
PXDNPeroxidasin. (1525 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (505 aa)
HPRT1Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (218 aa)
RDH5Retinol dehydrogenase 5; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (318 aa)
PPARDPeroxisome proliferator activated receptor delta. (441 aa)
ACTBUncharacterized protein. (375 aa)
IL6Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (237 aa)
RARBRetinoic acid receptor beta. (448 aa)
RBP3Retinol binding protein 3. (1286 aa)
TGFBR2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (550 aa)
TTRTransthyretin; Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain. (147 aa)
CRABP2Cellular retinoic acid binding protein 2; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (138 aa)
LTBP2Latent transforming growth factor beta binding protein 2. (1842 aa)
ENSCHIP00000003120Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (462 aa)
RORCRAR related orphan receptor C. (508 aa)
CD38Uncharacterized protein. (277 aa)
HSD17B2Hydroxysteroid 17-beta dehydrogenase 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (388 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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