(23 nodes) (2022) The MicroRNA-signaling-peroxisome proliferator-activated receptor gamma connection in the modulation of adipogenesis: bioinformatics projection on chicken. network (Capra hircus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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Your Input:
	LRP6	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1613 aa)
	LRP5	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1615 aa)
	ZNF423	Zinc finger protein 423. (1308 aa)
	BCL6	BCL6 transcription repressor. (706 aa)
	MAP3K1	Mitogen-activated protein kinase kinase kinase 1. (1507 aa)
	CTNNB1	Catenin beta 1. (781 aa)
	WNT1	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
	TGFB3	Transforming growth factor beta; Belongs to the TGF-beta family. (452 aa)
	SIRT1	Deacetylase sirtuin-type domain-containing protein. (732 aa)
	TGFBR2	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (550 aa)
	TGFB1	Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
	FGF10	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (213 aa)
	SMAD3	Mothers against decapentaplegic homolog. (425 aa)
	FOXO1	Forkhead box O1. (668 aa)
	TGFB2	Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
	TGFBR1	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (501 aa)
	STAT5A	Signal transducer and activator of transcription. (810 aa)
	MAP2K5	Mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily. (463 aa)
	STAT5B	Signal transducer and activator of transcription. (808 aa)
	MAP2K1	Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (397 aa)
	BMP4	Bone morphogenetic protein 4. (409 aa)
	SMAD2	Mothers against decapentaplegic homolog. (467 aa)
	FGF21	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (209 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BCL6	FOXO1	ENSCHIP00000032540	ENSCHIP00000018991	BCL6 transcription repressor.	Forkhead box O1.	0.821
BCL6	SIRT1	ENSCHIP00000032540	ENSCHIP00000007571	BCL6 transcription repressor.	Deacetylase sirtuin-type domain-containing protein.	0.691
BCL6	STAT5A	ENSCHIP00000032540	ENSCHIP00000025473	BCL6 transcription repressor.	Signal transducer and activator of transcription.	0.481
BCL6	STAT5B	ENSCHIP00000032540	ENSCHIP00000024716	BCL6 transcription repressor.	Signal transducer and activator of transcription.	0.472
BMP4	CTNNB1	ENSCHIP00000023678	ENSCHIP00000031016	Bone morphogenetic protein 4.	Catenin beta 1.	0.800
BMP4	FGF10	ENSCHIP00000023678	ENSCHIP00000010028	Bone morphogenetic protein 4.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.887
BMP4	FGF21	ENSCHIP00000023678	ENSCHIP00000030527	Bone morphogenetic protein 4.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.460
BMP4	LRP5	ENSCHIP00000023678	ENSCHIP00000021146	Bone morphogenetic protein 4.	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.	0.503
BMP4	LRP6	ENSCHIP00000023678	ENSCHIP00000013402	Bone morphogenetic protein 4.	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.	0.466
BMP4	SMAD2	ENSCHIP00000023678	ENSCHIP00000022106	Bone morphogenetic protein 4.	Mothers against decapentaplegic homolog.	0.866
BMP4	SMAD3	ENSCHIP00000023678	ENSCHIP00000011729	Bone morphogenetic protein 4.	Mothers against decapentaplegic homolog.	0.808
BMP4	TGFB1	ENSCHIP00000023678	ENSCHIP00000008885	Bone morphogenetic protein 4.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.495
BMP4	TGFBR1	ENSCHIP00000023678	ENSCHIP00000025782	Bone morphogenetic protein 4.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.799
BMP4	TGFBR2	ENSCHIP00000023678	ENSCHIP00000008226	Bone morphogenetic protein 4.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.657
BMP4	WNT1	ENSCHIP00000023678	ENSCHIP00000020293	Bone morphogenetic protein 4.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.618
CTNNB1	BMP4	ENSCHIP00000031016	ENSCHIP00000023678	Catenin beta 1.	Bone morphogenetic protein 4.	0.800
CTNNB1	FGF10	ENSCHIP00000031016	ENSCHIP00000010028	Catenin beta 1.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.668
CTNNB1	FGF21	ENSCHIP00000031016	ENSCHIP00000030527	Catenin beta 1.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.515
CTNNB1	FOXO1	ENSCHIP00000031016	ENSCHIP00000018991	Catenin beta 1.	Forkhead box O1.	0.858
CTNNB1	LRP5	ENSCHIP00000031016	ENSCHIP00000021146	Catenin beta 1.	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.	0.957