STRINGSTRING
CLIC3 CLIC3 SHMT2 SHMT2 CTLA4 CTLA4 ALDH1L1 ALDH1L1 CXCL12 CXCL12 CCT3 CCT3 MTHFD2L MTHFD2L PNO1 PNO1 MRPL49 MRPL49 SHMT1 SHMT1 CXCR4 CXCR4 PXDN PXDN PERM1 PERM1 IFNG IFNG PPT2 PPT2 CD274 CD274 CCNA2 CCNA2 CXXC5 CXXC5 WDHD1 WDHD1 CDH2 CDH2 SKP2 SKP2 ALDH1L2 ALDH1L2 CAVIN3 CAVIN3 MTHFD2 MTHFD2 PLK1 PLK1 MTHFR MTHFR MTHFD1L MTHFD1L MCM7 MCM7
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CLIC3Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (237 aa)
SHMT2Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (502 aa)
CTLA4Cytotoxic T-lymphocyte associated protein 4. (221 aa)
ALDH1L110-formyltetrahydrofolate dehydrogenase; In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily. (899 aa)
CXCL12C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family. (116 aa)
CCT3T-complex protein 1 subunit gamma. (545 aa)
MTHFD2LMethylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like. (347 aa)
PNO1Partner of NOB1 homolog. (252 aa)
MRPL49Mitochondrial ribosomal protein L49. (173 aa)
SHMT1Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (484 aa)
CXCR4C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family. (353 aa)
PXDNPeroxidasin. (1525 aa)
PERM1PPARGC1 and ESRR induced regulator, muscle 1. (862 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity); Belongs to the type II (or gamma) interferon family. (166 aa)
PPT2Palmitoyl-protein thioesterase 2. (330 aa)
CD274CD274 molecule. (289 aa)
CCNA2Cyclin A2; Belongs to the cyclin family. (430 aa)
CXXC5CXXC finger protein 5. (315 aa)
WDHD1WD repeat and HMG-box DNA binding protein 1. (1124 aa)
CDH2Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins. (906 aa)
SKP2F-box domain-containing protein. (424 aa)
ALDH1L210-formyltetrahydrofolate dehydrogenase; In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily. (923 aa)
CAVIN3Caveolae associated protein 3. (260 aa)
MTHFD2Uncharacterized protein. (352 aa)
PLK1Serine/threonine-protein kinase PLK. (602 aa)
MTHFRMethylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (655 aa)
MTHFD1LMethylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like. (975 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (719 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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