STRINGSTRING
PGAM1 PGAM1 LOC102171116 LOC102171116 EIF4A3 EIF4A3 TNP1 TNP1 STAT6 STAT6 EEF1B2 EEF1B2 SCIN SCIN ATF4 ATF4 BPGM BPGM PPIC PPIC PEPD PEPD LOC102178616 LOC102178616 STAT2 STAT2 LOC108638107 LOC108638107 FKBP3 FKBP3 PPIB PPIB LEP LEP EIF1 EIF1 STAT3 STAT3 EIF3F EIF3F STAT4 STAT4 GSN GSN PRP1 PRP1 STAT5B STAT5B EIF4A1 EIF4A1 STAT5A STAT5A EEF1G EEF1G CSNK2A1 CSNK2A1 EIF3F-2 EIF3F-2 LOC102180550 LOC102180550 PGAM2 PGAM2 STAT1 STAT1 PRP6 PRP6 INS INS EIF6 EIF6 EEF1D EEF1D EIF4A2 EIF4A2 LOC102170569 LOC102170569 LOC102184390 LOC102184390 LOC102190477 LOC102190477 LOC102172503 LOC102172503 EEF2 EEF2 CDC42 CDC42 LOC100861197 LOC100861197
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PGAM1Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (254 aa)
LOC102171116Uncharacterized protein. (226 aa)
EIF4A3Eukaryotic translation initiation factor 4A3; Belongs to the DEAD box helicase family. (411 aa)
TNP1Transition protein 1. (55 aa)
STAT6Signal transducer and activator of transcription. (841 aa)
EEF1B2Uncharacterized protein; Belongs to the EF-1-beta/EF-1-delta family. (225 aa)
SCINScinderin. (715 aa)
ATF4Activating transcription factor 4. (352 aa)
BPGMPhosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (259 aa)
PPICPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (212 aa)
PEPDPeptidase D. (493 aa)
LOC102178616Uncharacterized protein. (265 aa)
STAT2Signal transducer and activator of transcription. (851 aa)
LOC108638107Uncharacterized protein. (238 aa)
FKBP3Peptidylprolyl isomerase. (224 aa)
PPIBPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (216 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways (By similarity). In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, inc [...] (192 aa)
EIF1Eukaryotic translation initiation factor 1. (113 aa)
STAT3Signal transducer and activator of transcription. (770 aa)
EIF3FEukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (369 aa)
STAT4Signal transducer and activator of transcription. (797 aa)
GSNGelsolin. (785 aa)
PRP1Prolactin-related protein-1. (238 aa)
STAT5BSignal transducer and activator of transcription. (808 aa)
EIF4A1Eukaryotic translation initiation factor 4A1; Belongs to the DEAD box helicase family. (406 aa)
STAT5ASignal transducer and activator of transcription. (810 aa)
EEF1GUncharacterized protein. (440 aa)
CSNK2A1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (391 aa)
EIF3F-2Eukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (334 aa)
LOC102180550Uncharacterized protein. (237 aa)
PGAM2Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (253 aa)
STAT1Signal transducer and activator of transcription. (834 aa)
PRP6Prolactin-related protein-6. (239 aa)
INSInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (105 aa)
EIF6Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...] (245 aa)
EEF1DUncharacterized protein; Belongs to the EF-1-beta/EF-1-delta family. (280 aa)
EIF4A2Eukaryotic translation initiation factor 4A2; Belongs to the DEAD box helicase family. (408 aa)
LOC102170569Uncharacterized protein. (211 aa)
LOC102184390Uncharacterized protein. (287 aa)
LOC102190477Uncharacterized protein. (238 aa)
LOC102172503Eukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (369 aa)
EEF2Tr-type G domain-containing protein. (858 aa)
CDC42Uncharacterized protein. (191 aa)
LOC100861197Glutathione S-transferase P; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Regulates negatively CDK5 activity via p25/p35 translocation to prevent neurodegeneration (By similarity); Belongs to the GST superfamily. Pi family. (210 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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