17 items (Capra hircus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	NR4A1	Nuclear receptor subfamily 4 group A member 1. (623 aa)
	CCND1	Cyclin D1; Belongs to the cyclin family. (295 aa)
	FOXO4	Forkhead box O4. (535 aa)
	ACTB	Uncharacterized protein. (375 aa)
	CD163	CD163 molecule. (1114 aa)
	PCNA	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
	FOXO1	Forkhead box O1. (668 aa)
	FOXO6	Forkhead box O6. (567 aa)
	FOXO3	Forkhead box O3. (672 aa)
	ALB	Serum albumin. (608 aa)
	MTOR	Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2550 aa)
	NOX4	NADPH oxidase 4. (578 aa)
	GAPDH	Glyceraldehyde-3-phosphate dehydrogenase. (333 aa)
	CCNE1	Cyclin E1; Belongs to the cyclin family. (411 aa)
	TP53	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (382 aa)
	GLUL	Glutamine synthetase. (373 aa)
	CTNNB1	Catenin beta 1. (781 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTB	ALB	ENSCHIP00000011080	ENSCHIP00000020234	Uncharacterized protein.	Serum albumin.	0.961
ACTB	CCND1	ENSCHIP00000011080	ENSCHIP00000006815	Uncharacterized protein.	Cyclin D1; Belongs to the cyclin family.	0.890
ACTB	CCNE1	ENSCHIP00000011080	ENSCHIP00000029715	Uncharacterized protein.	Cyclin E1; Belongs to the cyclin family.	0.777
ACTB	CD163	ENSCHIP00000011080	ENSCHIP00000014907	Uncharacterized protein.	CD163 molecule.	0.670
ACTB	CTNNB1	ENSCHIP00000011080	ENSCHIP00000031016	Uncharacterized protein.	Catenin beta 1.	0.906
ACTB	FOXO1	ENSCHIP00000011080	ENSCHIP00000018991	Uncharacterized protein.	Forkhead box O1.	0.791
ACTB	FOXO3	ENSCHIP00000011080	ENSCHIP00000019148	Uncharacterized protein.	Forkhead box O3.	0.685
ACTB	FOXO4	ENSCHIP00000011080	ENSCHIP00000010782	Uncharacterized protein.	Forkhead box O4.	0.468
ACTB	GAPDH	ENSCHIP00000011080	ENSCHIP00000025974	Uncharacterized protein.	Glyceraldehyde-3-phosphate dehydrogenase.	0.979
ACTB	GLUL	ENSCHIP00000011080	ENSCHIP00000030828	Uncharacterized protein.	Glutamine synthetase.	0.599
ACTB	MTOR	ENSCHIP00000011080	ENSCHIP00000021872	Uncharacterized protein.	Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family.	0.734
ACTB	NOX4	ENSCHIP00000011080	ENSCHIP00000024501	Uncharacterized protein.	NADPH oxidase 4.	0.778
ACTB	TP53	ENSCHIP00000011080	ENSCHIP00000030141	Uncharacterized protein.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.907
ALB	ACTB	ENSCHIP00000020234	ENSCHIP00000011080	Serum albumin.	Uncharacterized protein.	0.961
ALB	CCND1	ENSCHIP00000020234	ENSCHIP00000006815	Serum albumin.	Cyclin D1; Belongs to the cyclin family.	0.780
ALB	CCNE1	ENSCHIP00000020234	ENSCHIP00000029715	Serum albumin.	Cyclin E1; Belongs to the cyclin family.	0.401
ALB	CD163	ENSCHIP00000020234	ENSCHIP00000014907	Serum albumin.	CD163 molecule.	0.715
ALB	CTNNB1	ENSCHIP00000020234	ENSCHIP00000031016	Serum albumin.	Catenin beta 1.	0.842
ALB	FOXO1	ENSCHIP00000020234	ENSCHIP00000018991	Serum albumin.	Forkhead box O1.	0.679
ALB	FOXO3	ENSCHIP00000020234	ENSCHIP00000019148	Serum albumin.	Forkhead box O3.	0.546