13 items (Capra hircus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	GPR12	G protein-coupled receptor 12; Belongs to the G-protein coupled receptor 1 family. (334 aa)
	COL5A2	Collagen type V alpha 2 chain. (1252 aa)
	FBN2	Fibrillin 2. (2900 aa)
	ACTB	Uncharacterized protein. (375 aa)
	ELN	Uncharacterized protein. (504 aa)
	FOXO3	Forkhead box O3. (672 aa)
	ALB	Serum albumin. (608 aa)
	CYP19A1	Aromatase; A cytochrome P450 monooxygenase that catalyzes the conversion of C19 androgens, androst-4-ene-3,17-dione (androstenedione) and testosterone to the C18 estrogens, estrone and estradiol, respectively. Catalyzes three successive oxidations of C19 androgens: two conventional oxidations at C19 yielding 19-hydroxy and 19-oxo/19- aldehyde derivatives, followed by a third oxidative aromatization step that involves C1-beta hydrogen abstraction combined with cleavage of the C10-C19 bond to yield a phenolic A ring and formic acid. Alternatively, the third oxidative reaction yields a 19 [...] (503 aa)
	COL12A1	Collagen type XII alpha 1 chain. (3046 aa)
	BMP4	Bone morphogenetic protein 4. (409 aa)
	COL4A1	Collagen type IV alpha 1 chain. (1608 aa)
	COL1A2	Collagen type I alpha 2 chain. (1128 aa)
	COL4A2	Collagen type IV alpha 2 chain. (1607 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTB	ALB	ENSCHIP00000011080	ENSCHIP00000020234	Uncharacterized protein.	Serum albumin.	0.961
ACTB	BMP4	ENSCHIP00000011080	ENSCHIP00000023678	Uncharacterized protein.	Bone morphogenetic protein 4.	0.697
ACTB	COL1A2	ENSCHIP00000011080	ENSCHIP00000031191	Uncharacterized protein.	Collagen type I alpha 2 chain.	0.563
ACTB	CYP19A1	ENSCHIP00000011080	ENSCHIP00000020521	Uncharacterized protein.	Aromatase; A cytochrome P450 monooxygenase that catalyzes the conversion of C19 androgens, androst-4-ene-3,17-dione (androstenedione) and testosterone to the C18 estrogens, estrone and estradiol, respectively. Catalyzes three successive oxidations of C19 androgens: two conventional oxidations at C19 yielding 19-hydroxy and 19-oxo/19- aldehyde derivatives, followed by a third oxidative aromatization step that involves C1-beta hydrogen abstraction combined with cleavage of the C10-C19 bond to yield a phenolic A ring and formic acid. Alternatively, the third oxidative reaction yields a 19 [...]	0.685
ACTB	ELN	ENSCHIP00000011080	ENSCHIP00000018772	Uncharacterized protein.	Uncharacterized protein.	0.519
ACTB	FOXO3	ENSCHIP00000011080	ENSCHIP00000019148	Uncharacterized protein.	Forkhead box O3.	0.685
ALB	ACTB	ENSCHIP00000020234	ENSCHIP00000011080	Serum albumin.	Uncharacterized protein.	0.961
ALB	BMP4	ENSCHIP00000020234	ENSCHIP00000023678	Serum albumin.	Bone morphogenetic protein 4.	0.745
ALB	COL1A2	ENSCHIP00000020234	ENSCHIP00000031191	Serum albumin.	Collagen type I alpha 2 chain.	0.488
ALB	CYP19A1	ENSCHIP00000020234	ENSCHIP00000020521	Serum albumin.	Aromatase; A cytochrome P450 monooxygenase that catalyzes the conversion of C19 androgens, androst-4-ene-3,17-dione (androstenedione) and testosterone to the C18 estrogens, estrone and estradiol, respectively. Catalyzes three successive oxidations of C19 androgens: two conventional oxidations at C19 yielding 19-hydroxy and 19-oxo/19- aldehyde derivatives, followed by a third oxidative aromatization step that involves C1-beta hydrogen abstraction combined with cleavage of the C10-C19 bond to yield a phenolic A ring and formic acid. Alternatively, the third oxidative reaction yields a 19 [...]	0.540
ALB	ELN	ENSCHIP00000020234	ENSCHIP00000018772	Serum albumin.	Uncharacterized protein.	0.725
ALB	FOXO3	ENSCHIP00000020234	ENSCHIP00000019148	Serum albumin.	Forkhead box O3.	0.546
BMP4	ACTB	ENSCHIP00000023678	ENSCHIP00000011080	Bone morphogenetic protein 4.	Uncharacterized protein.	0.697
BMP4	ALB	ENSCHIP00000023678	ENSCHIP00000020234	Bone morphogenetic protein 4.	Serum albumin.	0.745
BMP4	COL4A1	ENSCHIP00000023678	ENSCHIP00000025370	Bone morphogenetic protein 4.	Collagen type IV alpha 1 chain.	0.408
COL12A1	COL1A2	ENSCHIP00000020533	ENSCHIP00000031191	Collagen type XII alpha 1 chain.	Collagen type I alpha 2 chain.	0.698
COL12A1	COL4A1	ENSCHIP00000020533	ENSCHIP00000025370	Collagen type XII alpha 1 chain.	Collagen type IV alpha 1 chain.	0.491
COL12A1	COL4A2	ENSCHIP00000020533	ENSCHIP00000032096	Collagen type XII alpha 1 chain.	Collagen type IV alpha 2 chain.	0.763
COL12A1	COL5A2	ENSCHIP00000020533	ENSCHIP00000009695	Collagen type XII alpha 1 chain.	Collagen type V alpha 2 chain.	0.661
COL1A2	ACTB	ENSCHIP00000031191	ENSCHIP00000011080	Collagen type I alpha 2 chain.	Uncharacterized protein.	0.563