STRINGSTRING
LDH-A LDH-A NAMPT NAMPT ACTB ACTB LOC102181016 LOC102181016 GAPDHS GAPDHS PSPH PSPH LOC102176799 LOC102176799 SLC1A4 SLC1A4 TP53 TP53 PSAT1 PSAT1 GAPDH GAPDH SLC1A5 SLC1A5 PAX8 PAX8 RHO RHO PHGDH PHGDH PARP1 PARP1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LDH-AL-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (361 aa)
NAMPTNicotinamide phosphoribosyltransferase; Belongs to the NAPRTase family. (491 aa)
ACTBUncharacterized protein. (375 aa)
LOC102181016Gp_dh_N domain-containing protein; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (318 aa)
GAPDHSGlyceraldehyde-3-phosphate dehydrogenase. (385 aa)
PSPHPhosphoserine phosphatase. (225 aa)
LOC102176799Glyceraldehyde-3-phosphate dehydrogenase. (333 aa)
SLC1A4Solute carrier family 1 member 4. (527 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (382 aa)
PSAT1Phosphoserine aminotransferase. (370 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase. (333 aa)
SLC1A5Amino acid transporter. (530 aa)
PAX8Paired box 8. (457 aa)
RHORhodopsin. (348 aa)
PHGDHD-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (533 aa)
PARP1Poly [ADP-ribose] polymerase. (1020 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.