(13 nodes) (2022) Co-option of the piRNA pathway to regulate neural crest specification. network (Capra hircus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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Known Interactions

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Predicted Interactions

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Your Input:
	TPM4	Tropomyosin 4; Belongs to the tropomyosin family. (284 aa)
	TPM1	Uncharacterized protein; Belongs to the tropomyosin family. (284 aa)
	PIWIL2	Piwi like RNA-mediated gene silencing 2; Belongs to the argonaute family. (967 aa)
	PAX7	Paired box 7. (503 aa)
	SNAI2	Snail family transcriptional repressor 2. (268 aa)
	KITLG	Processed kit ligand; Stimulates the proliferation of mast cells. Able to augment the proliferation of both myeloid and lymphoid hematopoietic progenitors in bone marrow culture. Mediates also cell-cell adhesion. Acts synergistically with other cytokines, probably interleukins (By similarity); Belongs to the SCF family. (274 aa)
	PNLDC1	PARN like, ribonuclease domain containing 1. (530 aa)
	TPM3	Tropomyosin 3; Belongs to the tropomyosin family. (290 aa)
	ACTB	Uncharacterized protein. (375 aa)
	TDRD3	Tudor domain containing 3. (762 aa)
	TDRD1	Tudor domain containing 1. (1185 aa)
	TDRD9	Tudor domain containing 9. (1375 aa)
	MYB	MYB proto-oncogene, transcription factor. (640 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTB	KITLG	ENSCHIP00000011080	ENSCHIP00000030559	Uncharacterized protein.	Processed kit ligand; Stimulates the proliferation of mast cells. Able to augment the proliferation of both myeloid and lymphoid hematopoietic progenitors in bone marrow culture. Mediates also cell-cell adhesion. Acts synergistically with other cytokines, probably interleukins (By similarity); Belongs to the SCF family.	0.654
ACTB	PAX7	ENSCHIP00000011080	ENSCHIP00000027759	Uncharacterized protein.	Paired box 7.	0.523
ACTB	SNAI2	ENSCHIP00000011080	ENSCHIP00000029179	Uncharacterized protein.	Snail family transcriptional repressor 2.	0.721
ACTB	TPM1	ENSCHIP00000011080	ENSCHIP00000022213	Uncharacterized protein.	Uncharacterized protein; Belongs to the tropomyosin family.	0.511
ACTB	TPM3	ENSCHIP00000011080	ENSCHIP00000017836	Uncharacterized protein.	Tropomyosin 3; Belongs to the tropomyosin family.	0.501
ACTB	TPM4	ENSCHIP00000011080	ENSCHIP00000005470	Uncharacterized protein.	Tropomyosin 4; Belongs to the tropomyosin family.	0.504
KITLG	ACTB	ENSCHIP00000030559	ENSCHIP00000011080	Processed kit ligand; Stimulates the proliferation of mast cells. Able to augment the proliferation of both myeloid and lymphoid hematopoietic progenitors in bone marrow culture. Mediates also cell-cell adhesion. Acts synergistically with other cytokines, probably interleukins (By similarity); Belongs to the SCF family.	Uncharacterized protein.	0.654
PAX7	ACTB	ENSCHIP00000027759	ENSCHIP00000011080	Paired box 7.	Uncharacterized protein.	0.523
PAX7	SNAI2	ENSCHIP00000027759	ENSCHIP00000029179	Paired box 7.	Snail family transcriptional repressor 2.	0.643
PIWIL2	TDRD1	ENSCHIP00000026734	ENSCHIP00000010163	Piwi like RNA-mediated gene silencing 2; Belongs to the argonaute family.	Tudor domain containing 1.	0.964
PIWIL2	TDRD9	ENSCHIP00000026734	ENSCHIP00000008361	Piwi like RNA-mediated gene silencing 2; Belongs to the argonaute family.	Tudor domain containing 9.	0.842
PNLDC1	TDRD1	ENSCHIP00000001655	ENSCHIP00000010163	PARN like, ribonuclease domain containing 1.	Tudor domain containing 1.	0.718
PNLDC1	TDRD9	ENSCHIP00000001655	ENSCHIP00000008361	PARN like, ribonuclease domain containing 1.	Tudor domain containing 9.	0.689
SNAI2	ACTB	ENSCHIP00000029179	ENSCHIP00000011080	Snail family transcriptional repressor 2.	Uncharacterized protein.	0.721
SNAI2	PAX7	ENSCHIP00000029179	ENSCHIP00000027759	Snail family transcriptional repressor 2.	Paired box 7.	0.643
TDRD1	PIWIL2	ENSCHIP00000010163	ENSCHIP00000026734	Tudor domain containing 1.	Piwi like RNA-mediated gene silencing 2; Belongs to the argonaute family.	0.964
TDRD1	PNLDC1	ENSCHIP00000010163	ENSCHIP00000001655	Tudor domain containing 1.	PARN like, ribonuclease domain containing 1.	0.718
TDRD1	TDRD3	ENSCHIP00000010163	ENSCHIP00000021807	Tudor domain containing 1.	Tudor domain containing 3.	0.454
TDRD1	TDRD9	ENSCHIP00000010163	ENSCHIP00000008361	Tudor domain containing 1.	Tudor domain containing 9.	0.754
TDRD3	TDRD1	ENSCHIP00000021807	ENSCHIP00000010163	Tudor domain containing 3.	Tudor domain containing 1.	0.454