(6 nodes) (2022) Protective Effects of Recombinant Human Angiogenin in Keratinocytes: New Insights on Oxidative Stress Response Mediated by RNases. network (Capra hircus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HSPA6	Heat shock protein family A (Hsp70) member 6; Belongs to the heat shock protein 70 family. (643 aa)
	EIF4E	Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family. (217 aa)
	ACTB	Uncharacterized protein. (375 aa)
	RPS6	40S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (255 aa)
	GAPDH	Glyceraldehyde-3-phosphate dehydrogenase. (333 aa)
	PABPC1	Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (636 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTB	EIF4E	ENSCHIP00000011080	ENSCHIP00000005408	Uncharacterized protein.	Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family.	0.712
ACTB	GAPDH	ENSCHIP00000011080	ENSCHIP00000025974	Uncharacterized protein.	Glyceraldehyde-3-phosphate dehydrogenase.	0.979
ACTB	HSPA6	ENSCHIP00000011080	ENSCHIP00000030802	Uncharacterized protein.	Heat shock protein family A (Hsp70) member 6; Belongs to the heat shock protein 70 family.	0.484
ACTB	RPS6	ENSCHIP00000011080	ENSCHIP00000006669	Uncharacterized protein.	40S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family.	0.747
EIF4E	ACTB	ENSCHIP00000005408	ENSCHIP00000011080	Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family.	Uncharacterized protein.	0.712
EIF4E	GAPDH	ENSCHIP00000005408	ENSCHIP00000025974	Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family.	Glyceraldehyde-3-phosphate dehydrogenase.	0.712
EIF4E	PABPC1	ENSCHIP00000005408	ENSCHIP00000028120	Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family.	Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family.	0.979
EIF4E	RPS6	ENSCHIP00000005408	ENSCHIP00000006669	Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family.	40S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family.	0.910
GAPDH	ACTB	ENSCHIP00000025974	ENSCHIP00000011080	Glyceraldehyde-3-phosphate dehydrogenase.	Uncharacterized protein.	0.979
GAPDH	EIF4E	ENSCHIP00000025974	ENSCHIP00000005408	Glyceraldehyde-3-phosphate dehydrogenase.	Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family.	0.712
GAPDH	HSPA6	ENSCHIP00000025974	ENSCHIP00000030802	Glyceraldehyde-3-phosphate dehydrogenase.	Heat shock protein family A (Hsp70) member 6; Belongs to the heat shock protein 70 family.	0.613
GAPDH	PABPC1	ENSCHIP00000025974	ENSCHIP00000028120	Glyceraldehyde-3-phosphate dehydrogenase.	Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family.	0.440
GAPDH	RPS6	ENSCHIP00000025974	ENSCHIP00000006669	Glyceraldehyde-3-phosphate dehydrogenase.	40S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family.	0.750
HSPA6	ACTB	ENSCHIP00000030802	ENSCHIP00000011080	Heat shock protein family A (Hsp70) member 6; Belongs to the heat shock protein 70 family.	Uncharacterized protein.	0.484
HSPA6	GAPDH	ENSCHIP00000030802	ENSCHIP00000025974	Heat shock protein family A (Hsp70) member 6; Belongs to the heat shock protein 70 family.	Glyceraldehyde-3-phosphate dehydrogenase.	0.613
HSPA6	PABPC1	ENSCHIP00000030802	ENSCHIP00000028120	Heat shock protein family A (Hsp70) member 6; Belongs to the heat shock protein 70 family.	Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family.	0.791
PABPC1	EIF4E	ENSCHIP00000028120	ENSCHIP00000005408	Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family.	Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family.	0.979
PABPC1	GAPDH	ENSCHIP00000028120	ENSCHIP00000025974	Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family.	Glyceraldehyde-3-phosphate dehydrogenase.	0.440
PABPC1	HSPA6	ENSCHIP00000028120	ENSCHIP00000030802	Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family.	Heat shock protein family A (Hsp70) member 6; Belongs to the heat shock protein 70 family.	0.791
PABPC1	RPS6	ENSCHIP00000028120	ENSCHIP00000006669	Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family.	40S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family.	0.516