10 items (Capra hircus) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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textmining

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protein homology

Your Input:
	POLD3	Uncharacterized protein. (464 aa)
	POLD2	DNA polymerase delta 2, accessory subunit. (469 aa)
	RTEL1	Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...] (1212 aa)
	FANCM	FA complementation group M. (2043 aa)
	PCNA	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
	POLDIP3	DNA polymerase delta interacting protein 3. (421 aa)
	ALB	Serum albumin. (608 aa)
	POLD1	DNA polymerase. (1115 aa)
	TIPIN	TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (289 aa)
	RPS6KB1	Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (518 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALB	RPS6KB1	ENSCHIP00000020234	ENSCHIP00000002789	Serum albumin.	Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.	0.457
FANCM	PCNA	ENSCHIP00000013958	ENSCHIP00000015091	FA complementation group M.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.975
FANCM	POLD1	ENSCHIP00000013958	ENSCHIP00000019836	FA complementation group M.	DNA polymerase.	0.838
FANCM	POLD2	ENSCHIP00000013958	ENSCHIP00000005641	FA complementation group M.	DNA polymerase delta 2, accessory subunit.	0.472
FANCM	POLD3	ENSCHIP00000013958	ENSCHIP00000027965	FA complementation group M.	Uncharacterized protein.	0.536
FANCM	RTEL1	ENSCHIP00000013958	ENSCHIP00000012311	FA complementation group M.	Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...]	0.851
FANCM	TIPIN	ENSCHIP00000013958	ENSCHIP00000000682	FA complementation group M.	TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family.	0.589
PCNA	FANCM	ENSCHIP00000015091	ENSCHIP00000013958	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	FA complementation group M.	0.975
PCNA	POLD1	ENSCHIP00000015091	ENSCHIP00000019836	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	DNA polymerase.	0.990
PCNA	POLD2	ENSCHIP00000015091	ENSCHIP00000005641	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	DNA polymerase delta 2, accessory subunit.	0.989
PCNA	POLD3	ENSCHIP00000015091	ENSCHIP00000027965	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	Uncharacterized protein.	0.974
PCNA	RTEL1	ENSCHIP00000015091	ENSCHIP00000012311	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...]	0.572
POLD1	FANCM	ENSCHIP00000019836	ENSCHIP00000013958	DNA polymerase.	FA complementation group M.	0.838
POLD1	PCNA	ENSCHIP00000019836	ENSCHIP00000015091	DNA polymerase.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.990
POLD1	POLD2	ENSCHIP00000019836	ENSCHIP00000005641	DNA polymerase.	DNA polymerase delta 2, accessory subunit.	0.999
POLD1	POLD3	ENSCHIP00000019836	ENSCHIP00000027965	DNA polymerase.	Uncharacterized protein.	0.999
POLD1	RTEL1	ENSCHIP00000019836	ENSCHIP00000012311	DNA polymerase.	Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...]	0.507
POLD1	TIPIN	ENSCHIP00000019836	ENSCHIP00000000682	DNA polymerase.	TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family.	0.630
POLD2	FANCM	ENSCHIP00000005641	ENSCHIP00000013958	DNA polymerase delta 2, accessory subunit.	FA complementation group M.	0.472
POLD2	PCNA	ENSCHIP00000005641	ENSCHIP00000015091	DNA polymerase delta 2, accessory subunit.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.989