STRINGSTRING
CREB5 CREB5 PBRM1 PBRM1 SF3A1 SF3A1 LIN37 LIN37 BRD4 BRD4 SMARCB1 SMARCB1 SF3A3 SF3A3 PHF10 PHF10 BMP4 BMP4 GAPDH GAPDH MED11 MED11 ETV4 ETV4 SFPQ SFPQ DNTTIP1 DNTTIP1 IRX4 IRX4 CPSF2 CPSF2 LIN52 LIN52 SS18L1 SS18L1 NKX2-2 NKX2-2 SMARCAL1 SMARCAL1 FOXM1 FOXM1 SF3B4 SF3B4 MED22 MED22 SUMO2 SUMO2 NUDT21 NUDT21 SNRPA SNRPA NONO NONO LIN9 LIN9 ATF7IP ATF7IP FUS FUS SNRPC SNRPC ENSCHIP00000002848 ENSCHIP00000002848 SMARCC1 SMARCC1 GLI1 GLI1 ESS2 ESS2 ZNF462 ZNF462 LOC102176799 LOC102176799 MED30 MED30 TCF7L2 TCF7L2 GAPDHS GAPDHS DPF1 DPF1 CPSF6 CPSF6 ARID1A ARID1A ARID2 ARID2 SOX2 SOX2 SF3B2 SF3B2 PRPF40A PRPF40A LOC102172949 LOC102172949 SMARCE1 SMARCE1 RBM33 RBM33 BICRA BICRA LOC102181016 LOC102181016 ACTB ACTB FUBP1 FUBP1 NR0B1 NR0B1 PPP1R1A PPP1R1A CTCF CTCF CPSF4 CPSF4 CPSF7 CPSF7 TEAD1 TEAD1 LOC102176643 LOC102176643 CPSF1 CPSF1 SMARCD1 SMARCD1 CCNT2 CCNT2 PSPC1 PSPC1 CCNC CCNC CSTF2 CSTF2 MED13L MED13L NKX2-5 NKX2-5 SF3A2 SF3A2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CREB5cAMP responsive element binding protein 5. (549 aa)
PBRM1Polybromo 1. (1633 aa)
SF3A1Splicing factor 3a subunit 1. (808 aa)
LIN37Lin-37 DREAM MuvB core complex component. (240 aa)
BRD4Uncharacterized protein. (1336 aa)
SMARCB1SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; Belongs to the SNF5 family. (395 aa)
SF3A3Splicing factor 3a subunit 3. (501 aa)
PHF10PHD finger protein 10. (498 aa)
BMP4Bone morphogenetic protein 4. (409 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase. (333 aa)
MED11Mediator of RNA polymerase II transcription subunit 11; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (125 aa)
ETV4ETS variant 4. (490 aa)
SFPQSplicing factor proline and glutamine rich. (711 aa)
DNTTIP1Deoxynucleotidyltransferase terminal interacting protein 1. (329 aa)
IRX4Iroquois homeobox 4. (604 aa)
CPSF2Cleavage and polyadenylation specificity factor subunit 2. (782 aa)
LIN52Lin-52 DREAM MuvB core complex component. (116 aa)
SS18L1SS18L1 subunit of BAF chromatin remodeling complex. (402 aa)
NKX2-2NK2 homeobox 2. (273 aa)
SMARCAL1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1; Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily. (930 aa)
FOXM1Fork-head domain-containing protein. (763 aa)
SF3B4Uncharacterized protein. (424 aa)
MED22Mediator complex subunit 22. (203 aa)
SUMO2Small ubiquitin-related modifier. (95 aa)
NUDT21Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...] (227 aa)
SNRPASmall nuclear ribonucleoprotein polypeptide A. (282 aa)
NONONon-POU domain containing octamer binding. (470 aa)
LIN9Lin-9 DREAM MuvB core complex component. (558 aa)
ATF7IPActivating transcription factor 7 interacting protein. (1279 aa)
FUSFUS RNA binding protein. (522 aa)
SNRPCU1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. Belongs to the U1 [...] (152 aa)
ENSCHIP00000002848CYCLIN domain-containing protein; Belongs to the cyclin family. (236 aa)
SMARCC1SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1. (1093 aa)
GLI1GLI family zinc finger 1. (1105 aa)
ESS2Ess-2 splicing factor homolog. (480 aa)
ZNF462Zinc finger protein 462. (2502 aa)
LOC102176799Glyceraldehyde-3-phosphate dehydrogenase. (333 aa)
MED30Mediator complex subunit 30. (220 aa)
TCF7L2Transcription factor 7 like 2. (669 aa)
GAPDHSGlyceraldehyde-3-phosphate dehydrogenase. (385 aa)
DPF1Double PHD fingers 1. (414 aa)
CPSF6Cleavage and polyadenylation specific factor 6. (588 aa)
ARID1AAT-rich interaction domain 1A. (2285 aa)
ARID2AT-rich interaction domain 2. (1835 aa)
SOX2HMG box domain-containing protein. (320 aa)
SF3B2Splicing factor 3b subunit 2. (895 aa)
PRPF40APre-mRNA processing factor 40 homolog A. (890 aa)
LOC102172949U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. Belongs to the U1 [...] (159 aa)
SMARCE1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1. (411 aa)
RBM33RNA binding motif protein 33. (1129 aa)
BICRABRD4 interacting chromatin remodeling complex associated protein. (1578 aa)
LOC102181016Gp_dh_N domain-containing protein; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (318 aa)
ACTBUncharacterized protein. (375 aa)
FUBP1Uncharacterized protein. (685 aa)
NR0B1Nuclear receptor subfamily 0 group B member 1. (471 aa)
PPP1R1AProtein phosphatase 1 regulatory inhibitor subunit 1A. (162 aa)
CTCFCCCTC-binding factor. (727 aa)
CPSF4Cleavage and polyadenylation specific factor 4. (269 aa)
CPSF7Cleavage and polyadenylation specific factor 7. (471 aa)
TEAD1TEA domain transcription factor 1. (436 aa)
LOC102176643Tudor domain-containing protein. (295 aa)
CPSF1Cleavage and polyadenylation specific factor 1. (1415 aa)
SMARCD1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1. (515 aa)
CCNT2Cyclin T2; Belongs to the cyclin family. (725 aa)
PSPC1Paraspeckle component 1. (520 aa)
CCNCUncharacterized protein; Belongs to the cyclin family. (283 aa)
CSTF2Cleavage stimulation factor subunit 2. (592 aa)
MED13LMediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (2210 aa)
NKX2-5NK2 homeobox 5. (323 aa)
SF3A2Splicing factor 3a subunit 2. (477 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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