(18 nodes) (2022) Cellular shape reinforces niche to stem cell signaling in the small intestine. network (Capra hircus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MYH9	Myosin heavy chain 9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1986 aa)
	MYL2	Myosin light chain 2. (178 aa)
	AXIN2	Axin 2. (844 aa)
	SOX9	SRY-box transcription factor 9. (525 aa)
	EPCAM	Epithelial cell adhesion molecule. (314 aa)
	RSPO1	Ovarian R-spondin member 1. (262 aa)
	NOG	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
	OLFM4	Olfactomedin 4. (543 aa)
	LRIG1	Leucine rich repeats and immunoglobulin like domains 1. (1089 aa)
	MEX3A	Mex-3 RNA binding family member A. (520 aa)
	ACTB	Uncharacterized protein. (375 aa)
	CD24	Uncharacterized protein. (78 aa)
	WNT3A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (363 aa)
	BMI1	RING-type domain-containing protein. (437 aa)
	LGR5	Leucine rich repeat containing G protein-coupled receptor 5. (907 aa)
	MYH10	Myosin heavy chain 10; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1975 aa)
	WNT3	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (358 aa)
	ALB	Serum albumin. (608 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTB	ALB	ENSCHIP00000011080	ENSCHIP00000020234	Uncharacterized protein.	Serum albumin.	0.961
ACTB	AXIN2	ENSCHIP00000011080	ENSCHIP00000022676	Uncharacterized protein.	Axin 2.	0.666
ACTB	BMI1	ENSCHIP00000011080	ENSCHIP00000016491	Uncharacterized protein.	RING-type domain-containing protein.	0.697
ACTB	CD24	ENSCHIP00000011080	ENSCHIP00000013924	Uncharacterized protein.	Uncharacterized protein.	0.679
ACTB	EPCAM	ENSCHIP00000011080	ENSCHIP00000026828	Uncharacterized protein.	Epithelial cell adhesion molecule.	0.658
ACTB	LGR5	ENSCHIP00000011080	ENSCHIP00000019084	Uncharacterized protein.	Leucine rich repeat containing G protein-coupled receptor 5.	0.643
ACTB	MYH10	ENSCHIP00000011080	ENSCHIP00000019825	Uncharacterized protein.	Myosin heavy chain 10; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.952
ACTB	MYH9	ENSCHIP00000011080	ENSCHIP00000021370	Uncharacterized protein.	Myosin heavy chain 9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.964
ACTB	MYL2	ENSCHIP00000011080	ENSCHIP00000021875	Uncharacterized protein.	Myosin light chain 2.	0.582
ACTB	NOG	ENSCHIP00000011080	ENSCHIP00000005264	Uncharacterized protein.	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite.	0.580
ACTB	SOX9	ENSCHIP00000011080	ENSCHIP00000024523	Uncharacterized protein.	SRY-box transcription factor 9.	0.763
ACTB	WNT3	ENSCHIP00000011080	ENSCHIP00000020033	Uncharacterized protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.431
ACTB	WNT3A	ENSCHIP00000011080	ENSCHIP00000015590	Uncharacterized protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.720
ALB	ACTB	ENSCHIP00000020234	ENSCHIP00000011080	Serum albumin.	Uncharacterized protein.	0.961
ALB	AXIN2	ENSCHIP00000020234	ENSCHIP00000022676	Serum albumin.	Axin 2.	0.519
ALB	BMI1	ENSCHIP00000020234	ENSCHIP00000016491	Serum albumin.	RING-type domain-containing protein.	0.495
ALB	CD24	ENSCHIP00000020234	ENSCHIP00000013924	Serum albumin.	Uncharacterized protein.	0.659
ALB	EPCAM	ENSCHIP00000020234	ENSCHIP00000026828	Serum albumin.	Epithelial cell adhesion molecule.	0.718
ALB	LGR5	ENSCHIP00000020234	ENSCHIP00000019084	Serum albumin.	Leucine rich repeat containing G protein-coupled receptor 5.	0.570
ALB	NOG	ENSCHIP00000020234	ENSCHIP00000005264	Serum albumin.	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite.	0.781