17 items (Capra hircus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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co-expression

protein homology

Your Input:
	SHMT1	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (484 aa)
	MAPK14	Mitogen-activated protein kinase. (350 aa)
	SHMT2	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (502 aa)
	SOD2	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (222 aa)
	SRPK1	SRSF protein kinase 1. (645 aa)
	CXCL10	C-X-C motif chemokine. (102 aa)
	IL10	Interleukin 10. (177 aa)
	PHGDH	D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (533 aa)
	TLR4	TIR domain-containing protein; Belongs to the Toll-like receptor family. (841 aa)
	ALB	Serum albumin. (608 aa)
	RSAD2	Radical S-adenosyl methionine domain containing 2. (364 aa)
	TLR6	Toll-like receptor. (966 aa)
	GAPDH	Glyceraldehyde-3-phosphate dehydrogenase. (333 aa)
	PSAT1	Phosphoserine aminotransferase. (370 aa)
	MAPK13	Mitogen-activated protein kinase. (366 aa)
	DNM1L	Dynamin 1 like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (707 aa)
	IL1B	Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (266 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALB	CXCL10	ENSCHIP00000020234	ENSCHIP00000014303	Serum albumin.	C-X-C motif chemokine.	0.700
ALB	GAPDH	ENSCHIP00000020234	ENSCHIP00000025974	Serum albumin.	Glyceraldehyde-3-phosphate dehydrogenase.	0.948
ALB	IL10	ENSCHIP00000020234	ENSCHIP00000016929	Serum albumin.	Interleukin 10.	0.864
ALB	IL1B	ENSCHIP00000020234	ENSCHIP00000029274	Serum albumin.	Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family.	0.892
ALB	MAPK14	ENSCHIP00000020234	ENSCHIP00000000781	Serum albumin.	Mitogen-activated protein kinase.	0.408
ALB	SOD2	ENSCHIP00000020234	ENSCHIP00000006131	Serum albumin.	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.	0.653
ALB	TLR4	ENSCHIP00000020234	ENSCHIP00000019512	Serum albumin.	TIR domain-containing protein; Belongs to the Toll-like receptor family.	0.838
ALB	TLR6	ENSCHIP00000020234	ENSCHIP00000025720	Serum albumin.	Toll-like receptor.	0.843
CXCL10	ALB	ENSCHIP00000014303	ENSCHIP00000020234	C-X-C motif chemokine.	Serum albumin.	0.700
CXCL10	GAPDH	ENSCHIP00000014303	ENSCHIP00000025974	C-X-C motif chemokine.	Glyceraldehyde-3-phosphate dehydrogenase.	0.780
CXCL10	IL10	ENSCHIP00000014303	ENSCHIP00000016929	C-X-C motif chemokine.	Interleukin 10.	0.959
CXCL10	IL1B	ENSCHIP00000014303	ENSCHIP00000029274	C-X-C motif chemokine.	Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family.	0.911
CXCL10	RSAD2	ENSCHIP00000014303	ENSCHIP00000024819	C-X-C motif chemokine.	Radical S-adenosyl methionine domain containing 2.	0.798
CXCL10	TLR4	ENSCHIP00000014303	ENSCHIP00000019512	C-X-C motif chemokine.	TIR domain-containing protein; Belongs to the Toll-like receptor family.	0.790
CXCL10	TLR6	ENSCHIP00000014303	ENSCHIP00000025720	C-X-C motif chemokine.	Toll-like receptor.	0.825
DNM1L	RSAD2	ENSCHIP00000028514	ENSCHIP00000024819	Dynamin 1 like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Radical S-adenosyl methionine domain containing 2.	0.466
GAPDH	ALB	ENSCHIP00000025974	ENSCHIP00000020234	Glyceraldehyde-3-phosphate dehydrogenase.	Serum albumin.	0.948
GAPDH	CXCL10	ENSCHIP00000025974	ENSCHIP00000014303	Glyceraldehyde-3-phosphate dehydrogenase.	C-X-C motif chemokine.	0.780
GAPDH	IL10	ENSCHIP00000025974	ENSCHIP00000016929	Glyceraldehyde-3-phosphate dehydrogenase.	Interleukin 10.	0.885
GAPDH	IL1B	ENSCHIP00000025974	ENSCHIP00000029274	Glyceraldehyde-3-phosphate dehydrogenase.	Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family.	0.932