28 items (Capra hircus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DDX3X	Uncharacterized protein; Belongs to the DEAD box helicase family. (661 aa)
	DDX21	Uncharacterized protein. (754 aa)
	LIG4	DNA ligase. (911 aa)
	DDX39B	DExD-box helicase 39B. (428 aa)
	DDX41	DEAD-box helicase 41. (622 aa)
	DDX5	DEAD-box helicase 5; Belongs to the DEAD box helicase family. (622 aa)
	BTBD19	BTB domain containing 19. (291 aa)
	MYC	Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (439 aa)
	PCNA	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
	PXDN	Peroxidasin. (1525 aa)
	EME1	Essential meiotic structure-specific endonuclease 1. (580 aa)
	SLX4	SLX4 structure-specific endonuclease subunit. (1752 aa)
	SNRPN	Small nuclear ribonucleoprotein-associated protein. (240 aa)
	ELL	Elongation factor for RNA polymerase II. (599 aa)
	DHX9	DExH-box helicase 9. (1271 aa)
	SETX	Senataxin. (2659 aa)
	ENDOG	Endonuclease. (299 aa)
	DDX17	DEAD-box helicase 17; Belongs to the DEAD box helicase family. (729 aa)
	RPL13A	Uncharacterized protein; Belongs to the universal ribosomal protein uL13 family. (203 aa)
	APOE	Apolipoprotein E. (326 aa)
	MUS81	MUS81 structure-specific endonuclease subunit. (552 aa)
	HLTF	Helicase like transcription factor. (1011 aa)
	TOP1	DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (767 aa)
	SMARCAL1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1; Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily. (930 aa)
	GADD45A	Growth arrest and DNA damage inducible alpha. (165 aa)
	ZRANB3	Zinc finger RANBP2-type containing 3. (1070 aa)
	DHX15	DEAH-box helicase 15. (795 aa)
	RAD51	DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (339 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APOE	PXDN	ENSCHIP00000025098	ENSCHIP00000015493	Apolipoprotein E.	Peroxidasin.	0.717
BTBD19	RPL13A	ENSCHIP00000011355	ENSCHIP00000024652	BTB domain containing 19.	Uncharacterized protein; Belongs to the universal ribosomal protein uL13 family.	0.549
BTBD19	SETX	ENSCHIP00000011355	ENSCHIP00000022951	BTB domain containing 19.	Senataxin.	0.445
BTBD19	SNRPN	ENSCHIP00000011355	ENSCHIP00000017774	BTB domain containing 19.	Small nuclear ribonucleoprotein-associated protein.	0.449
DDX17	DDX21	ENSCHIP00000023972	ENSCHIP00000000347	DEAD-box helicase 17; Belongs to the DEAD box helicase family.	Uncharacterized protein.	0.429
DDX17	DDX39B	ENSCHIP00000023972	ENSCHIP00000002143	DEAD-box helicase 17; Belongs to the DEAD box helicase family.	DExD-box helicase 39B.	0.532
DDX17	DDX3X	ENSCHIP00000023972	ENSCHIP00000029996	DEAD-box helicase 17; Belongs to the DEAD box helicase family.	Uncharacterized protein; Belongs to the DEAD box helicase family.	0.684
DDX17	DDX41	ENSCHIP00000023972	ENSCHIP00000005738	DEAD-box helicase 17; Belongs to the DEAD box helicase family.	DEAD-box helicase 41.	0.407
DDX17	DDX5	ENSCHIP00000023972	ENSCHIP00000008777	DEAD-box helicase 17; Belongs to the DEAD box helicase family.	DEAD-box helicase 5; Belongs to the DEAD box helicase family.	0.893
DDX17	DHX15	ENSCHIP00000023972	ENSCHIP00000032306	DEAD-box helicase 17; Belongs to the DEAD box helicase family.	DEAH-box helicase 15.	0.675
DDX17	DHX9	ENSCHIP00000023972	ENSCHIP00000019777	DEAD-box helicase 17; Belongs to the DEAD box helicase family.	DExH-box helicase 9.	0.914
DDX21	DDX17	ENSCHIP00000000347	ENSCHIP00000023972	Uncharacterized protein.	DEAD-box helicase 17; Belongs to the DEAD box helicase family.	0.429
DDX21	DDX39B	ENSCHIP00000000347	ENSCHIP00000002143	Uncharacterized protein.	DExD-box helicase 39B.	0.509
DDX21	DDX3X	ENSCHIP00000000347	ENSCHIP00000029996	Uncharacterized protein.	Uncharacterized protein; Belongs to the DEAD box helicase family.	0.555
DDX21	DDX41	ENSCHIP00000000347	ENSCHIP00000005738	Uncharacterized protein.	DEAD-box helicase 41.	0.511
DDX21	DDX5	ENSCHIP00000000347	ENSCHIP00000008777	Uncharacterized protein.	DEAD-box helicase 5; Belongs to the DEAD box helicase family.	0.406
DDX21	DHX15	ENSCHIP00000000347	ENSCHIP00000032306	Uncharacterized protein.	DEAH-box helicase 15.	0.720
DDX21	DHX9	ENSCHIP00000000347	ENSCHIP00000019777	Uncharacterized protein.	DExH-box helicase 9.	0.923
DDX21	HLTF	ENSCHIP00000000347	ENSCHIP00000028650	Uncharacterized protein.	Helicase like transcription factor.	0.427
DDX21	SETX	ENSCHIP00000000347	ENSCHIP00000022951	Uncharacterized protein.	Senataxin.	0.573