STRINGSTRING
TP53 TP53 LOC102191748 LOC102191748 LOC102185882 LOC102185882 LOC108633554 LOC108633554 NUP205 NUP205 CDKN1A CDKN1A LOC102182848 LOC102182848 LOC108636012 LOC108636012 H3-4 H3-4 LOC108634231 LOC108634231 LOC102180554 LOC102180554 LOC106503499 LOC106503499 LOC108633916 LOC108633916 TMPO TMPO LOC102171353 LOC102171353 LOC102169981 LOC102169981 LMNB2 LMNB2 LMNB1 LMNB1 PXDN PXDN PDX1 PDX1 E2F4 E2F4 NUP155 NUP155 NUP85 NUP85 NUP210 NUP210 COL1A1 COL1A1 LOC102189503 LOC102189503 GAPDH GAPDH PLK1 PLK1 NUP35 NUP35 MMUT MMUT NUP107 NUP107 NUP54 NUP54
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (382 aa)
LOC102191748Histone domain-containing protein. (136 aa)
LOC102185882Histone H3; Belongs to the histone H3 family. (136 aa)
LOC108633554Histone domain-containing protein. (136 aa)
NUP205Nucleoporin 205. (2003 aa)
CDKN1ACyclin dependent kinase inhibitor 1A. (161 aa)
LOC102182848Histone H3; Belongs to the histone H3 family. (136 aa)
LOC108636012Histone H3; Belongs to the histone H3 family. (136 aa)
H3-4Histone H3; Belongs to the histone H3 family. (136 aa)
LOC108634231Histone H3; Belongs to the histone H3 family. (136 aa)
LOC102180554Histone H3; Belongs to the histone H3 family. (136 aa)
LOC106503499Histone H3; Belongs to the histone H3 family. (136 aa)
LOC108633916Histone H3; Belongs to the histone H3 family. (136 aa)
TMPOThymopoietin. (689 aa)
LOC102171353Histone H3; Belongs to the histone H3 family. (136 aa)
LOC102169981Histone domain-containing protein. (136 aa)
LMNB2Lamin B2; Belongs to the intermediate filament family. (641 aa)
LMNB1Lamin B1; Belongs to the intermediate filament family. (586 aa)
PXDNPeroxidasin. (1525 aa)
PDX1Pancreatic and duodenal homeobox 1. (284 aa)
E2F4E2F transcription factor 4. (405 aa)
NUP155Nucleoporin 155. (1391 aa)
NUP85Nuclear pore complex protein Nup85; Functions as a component of the nuclear pore complex (NPC). (656 aa)
NUP210Nucleoporin 210. (1889 aa)
COL1A1Collagen type I alpha 1 chain. (1463 aa)
LOC102189503Histone H3; Belongs to the histone H3 family. (136 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase. (333 aa)
PLK1Serine/threonine-protein kinase PLK. (602 aa)
NUP35Nucleoporin NUP53; Functions as a component of the nuclear pore complex (NPC). Belongs to the Nup35 family. (310 aa)
MMUTMethylmalonyl-CoA mutase. (771 aa)
NUP107Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC). (925 aa)
NUP54Nucleoporin 54. (510 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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