31 items (Capra hircus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HOXD11	Homeobox D11. (337 aa)
	HOXC6	Homeobox C6. (235 aa)
	TBX6	T-box transcription factor 6. (437 aa)
	ACVR2A	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (521 aa)
	GPM6A	Glycoprotein M6A. (278 aa)
	CYP26A1	Cytochrome P450 family 26 subfamily A member 1; Belongs to the cytochrome P450 family. (497 aa)
	HDAC5	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1142 aa)
	HDAC4	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1089 aa)
	SOX1	SRY-box transcription factor 1. (313 aa)
	SMAD4	Mothers against decapentaplegic homolog. (513 aa)
	SMAD2	Mothers against decapentaplegic homolog. (467 aa)
	HOXA11	Homeobox A11. (317 aa)
	POU5F1	POU domain protein. (360 aa)
	GLDC	Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. (1020 aa)
	UIMC1	Ubiquitin interaction motif containing 1. (795 aa)
	NR6A1	Nuclear receptor subfamily 6 group A member 1. (479 aa)
	HOXD9	Homeobox D9. (351 aa)
	CDX2	Caudal type homeobox 2. (306 aa)
	HOXC13	Homeobox C13. (330 aa)
	HDAC9	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1069 aa)
	ALDH1A2	Aldehyde dehydrogenase 1 family member A2; Belongs to the aldehyde dehydrogenase family. (518 aa)
	HOXB13	Homeobox B13. (285 aa)
	EPHA5	EPH receptor A5. (1031 aa)
	HOXD13	Homeobox D13. (340 aa)
	NCOR1	Nuclear receptor corepressor 1. (2447 aa)
	NKX1-2	NK1 homeobox 2. (301 aa)
	HOXA13	Homeobox A13. (388 aa)
	HOXC12	Homeobox C12. (278 aa)
	HOXC10	Homeobox C10. (342 aa)
	ACVR2B	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (522 aa)
	HDAC7	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1062 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACVR2A	ACVR2B	ENSCHIP00000011113	ENSCHIP00000010776	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.980
ACVR2A	SMAD2	ENSCHIP00000011113	ENSCHIP00000022106	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Mothers against decapentaplegic homolog.	0.984
ACVR2A	SMAD4	ENSCHIP00000011113	ENSCHIP00000020573	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Mothers against decapentaplegic homolog.	0.875
ACVR2B	ACVR2A	ENSCHIP00000010776	ENSCHIP00000011113	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.980
ACVR2B	SMAD2	ENSCHIP00000010776	ENSCHIP00000022106	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Mothers against decapentaplegic homolog.	0.985
ACVR2B	SMAD4	ENSCHIP00000010776	ENSCHIP00000020573	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Mothers against decapentaplegic homolog.	0.864
ALDH1A2	CYP26A1	ENSCHIP00000031730	ENSCHIP00000016557	Aldehyde dehydrogenase 1 family member A2; Belongs to the aldehyde dehydrogenase family.	Cytochrome P450 family 26 subfamily A member 1; Belongs to the cytochrome P450 family.	0.960
CDX2	POU5F1	ENSCHIP00000029734	ENSCHIP00000023987	Caudal type homeobox 2.	POU domain protein.	0.847
CDX2	SOX1	ENSCHIP00000029734	ENSCHIP00000019659	Caudal type homeobox 2.	SRY-box transcription factor 1.	0.585
CDX2	TBX6	ENSCHIP00000029734	ENSCHIP00000010988	Caudal type homeobox 2.	T-box transcription factor 6.	0.629
CYP26A1	ALDH1A2	ENSCHIP00000016557	ENSCHIP00000031730	Cytochrome P450 family 26 subfamily A member 1; Belongs to the cytochrome P450 family.	Aldehyde dehydrogenase 1 family member A2; Belongs to the aldehyde dehydrogenase family.	0.960
CYP26A1	TBX6	ENSCHIP00000016557	ENSCHIP00000010988	Cytochrome P450 family 26 subfamily A member 1; Belongs to the cytochrome P450 family.	T-box transcription factor 6.	0.557
HDAC4	HDAC5	ENSCHIP00000019494	ENSCHIP00000016766	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	0.916
HDAC4	HDAC9	ENSCHIP00000019494	ENSCHIP00000031505	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	0.411
HDAC4	NCOR1	ENSCHIP00000019494	ENSCHIP00000005863	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Nuclear receptor corepressor 1.	0.747
HDAC4	SMAD2	ENSCHIP00000019494	ENSCHIP00000022106	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Mothers against decapentaplegic homolog.	0.598
HDAC4	SMAD4	ENSCHIP00000019494	ENSCHIP00000020573	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Mothers against decapentaplegic homolog.	0.467
HDAC5	HDAC4	ENSCHIP00000016766	ENSCHIP00000019494	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	0.916
HDAC5	NCOR1	ENSCHIP00000016766	ENSCHIP00000005863	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Nuclear receptor corepressor 1.	0.737
HDAC7	NCOR1	ENSCHIP00000009920	ENSCHIP00000005863	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Nuclear receptor corepressor 1.	0.752