STRINGSTRING
NRXN1-2 NRXN1-2 ACSL4 ACSL4 KRT5 KRT5 TAGLN3 TAGLN3 KERA KERA LOC108633809 LOC108633809 TYR TYR FUCA1 FUCA1 CDKN1A CDKN1A BGN BGN EID1 EID1 POSTN POSTN TRPM1 TRPM1 SIX3 SIX3 LAMA5 LAMA5 NANOG NANOG COL5A2 COL5A2 CENPF CENPF TOP2A TOP2A HLA-DRA HLA-DRA MUC4 MUC4 MYL3 MYL3 PLA2G7 PLA2G7 GNAT2 GNAT2 MLANA MLANA TAGLN TAGLN KRT14 KRT14 GPHA2 GPHA2 MYL4 MYL4 VSX2 VSX2 CCL20 CCL20 AREG AREG CDKN1B CDKN1B TTN TTN ACE2 ACE2 COL8A1 COL8A1 NRXN1 NRXN1 MYH6 MYH6 ATP1A1 ATP1A1 CCNA2 CCNA2 ACTA2 ACTA2 DCN DCN GPC3 GPC3 NID2 NID2 KRT15 KRT15 MUC20 MUC20 CLDN5 CLDN5 TNNT2 TNNT2 NID1 NID1 IGF2 IGF2 COL1A1 COL1A1 COL4A1 COL4A1 MUC1 MUC1 KRT3 KRT3 MMP3 MMP3 SMO SMO PAX6 PAX6 ATP1B1 ATP1B1 LUM LUM COL8A2 COL8A2 MUC15 MUC15 IL1B IL1B TMPRSS2 TMPRSS2 KRT19 KRT19 LYVE1 LYVE1 ALDH3A1 ALDH3A1 COL1A2 COL1A2 CCL21 CCL21 NNAT NNAT COL4A2 COL4A2 TYRP1 TYRP1 COL15A1 COL15A1 LOC102180880 LOC102180880 ATP1B3 ATP1B3 TAGLN2 TAGLN2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NRXN1-2LAM_G_DOMAIN domain-containing protein. (467 aa)
ACSL4Acyl-CoA synthetase long chain family member 4. (711 aa)
KRT5Keratin 5; Belongs to the intermediate filament family. (561 aa)
TAGLN3Transgelin; Belongs to the calponin family. (199 aa)
KERAKeratocan. (352 aa)
LOC108633809Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (279 aa)
TYRTyrosinase. (530 aa)
FUCA1Alpha-L-fucosidase; Alpha-L-fucosidase is responsible for hydrolyzing the alpha- 1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. (471 aa)
CDKN1ACyclin dependent kinase inhibitor 1A. (161 aa)
BGNBiglycan; May be involved in collagen fiber assembly. Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily. (373 aa)
EID1Uncharacterized protein. (191 aa)
POSTNPeriostin. (836 aa)
TRPM1Transient receptor potential cation channel subfamily M member 1. (1654 aa)
SIX3SIX homeobox 3. (325 aa)
LAMA5Laminin subunit alpha 5. (2263 aa)
NANOGHomeobox domain-containing protein. (300 aa)
COL5A2Collagen type V alpha 2 chain. (1252 aa)
CENPFCentromere protein F. (3055 aa)
TOP2ADNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1538 aa)
HLA-DRAMajor histocompatibility complex, class II, DR alpha; Belongs to the MHC class II family. (253 aa)
MUC4Uncharacterized protein. (1083 aa)
MYL3Myosin light chain 3. (194 aa)
PLA2G7Platelet-activating factor acetylhydrolase. (444 aa)
GNAT2G protein subunit alpha transducin 2. (354 aa)
MLANAMelan-A. (118 aa)
TAGLNTransgelin; Belongs to the calponin family. (201 aa)
KRT14Keratin 14; Belongs to the intermediate filament family. (514 aa)
GPHA2Glycoprotein hormone subunit alpha 2. (129 aa)
MYL4Myosin light chain 4. (193 aa)
VSX2Visual system homeobox 2. (334 aa)
CCL20C-C motif chemokine. (96 aa)
AREGAmphiregulin. (264 aa)
CDKN1BCyclin dependent kinase inhibitor 1B. (198 aa)
TTNUncharacterized protein. (2149 aa)
ACE2Angiotensin-converting enzyme. (804 aa)
COL8A1Collagen type VIII alpha 1 chain. (745 aa)
NRXN1Neurexin 1. (853 aa)
MYH6Myosin heavy chain 6; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1943 aa)
ATP1A1Sodium/potassium-transporting ATPase subunit alpha. (1028 aa)
CCNA2Cyclin A2; Belongs to the cyclin family. (430 aa)
ACTA2Actin alpha 2, smooth muscle. (377 aa)
DCNDecorin; May affect the rate of fibrils formation. (360 aa)
GPC3Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (509 aa)
NID2Nidogen 2. (1305 aa)
KRT15Keratin 15; Belongs to the intermediate filament family. (453 aa)
MUC20Uncharacterized protein. (514 aa)
CLDN5Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (218 aa)
TNNT2Troponin T2, cardiac type. (267 aa)
NID1Nidogen 1. (1252 aa)
IGF2Insulin-like growth factor II. (179 aa)
COL1A1Collagen type I alpha 1 chain. (1463 aa)
COL4A1Collagen type IV alpha 1 chain. (1608 aa)
MUC1SEA domain-containing protein. (578 aa)
KRT3Keratin 3; Belongs to the intermediate filament family. (629 aa)
MMP3Matrix metallopeptidase 3. (477 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (780 aa)
PAX6Paired box 6. (486 aa)
ATP1B1Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (303 aa)
LUMLumican. (342 aa)
COL8A2Collagen type VIII alpha 2 chain. (704 aa)
MUC15Mucin 15, cell surface associated. (330 aa)
IL1BInterleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (266 aa)
TMPRSS2Transmembrane serine protease 2; Belongs to the peptidase S1 family. (492 aa)
KRT19Keratin 19; Belongs to the intermediate filament family. (399 aa)
LYVE1Lymphatic vessel endothelial hyaluronan receptor 1. (322 aa)
ALDH3A1Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (453 aa)
COL1A2Collagen type I alpha 2 chain. (1128 aa)
CCL21C-C motif chemokine ligand 21. (131 aa)
NNATNeuronatin. (81 aa)
COL4A2Collagen type IV alpha 2 chain. (1607 aa)
TYRP1Uncharacterized protein. (537 aa)
COL15A1Collagen type XV alpha 1 chain. (1375 aa)
LOC102180880C-C motif chemokine. (92 aa)
ATP1B3ATPase Na+/K+ transporting subunit beta 3. (279 aa)
TAGLN2Transgelin; Belongs to the calponin family. (199 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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