STRINGSTRING
HK3 HK3 GOT1 GOT1 PKM PKM PAH PAH LDH-A LDH-A HK2 HK2 IL6 IL6 TGFB1 TGFB1 HKDC1 HKDC1 PKLR PKLR OCLN OCLN HK1 HK1 GOT2 GOT2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HK3Hexokinase 3. (924 aa)
GOT1Aspartate aminotransferase. (413 aa)
PKMPyruvate kinase; Belongs to the pyruvate kinase family. (531 aa)
PAHPhenylalanine hydroxylase. (466 aa)
LDH-AL-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (361 aa)
HK2Hexokinase 2. (917 aa)
IL6Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (237 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
HKDC1Hexokinase domain containing 1. (918 aa)
PKLRPyruvate kinase; Belongs to the pyruvate kinase family. (575 aa)
OCLNOccludin; May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. Belongs to the ELL/occludin family. (522 aa)
HK1Hexokinase 1. (945 aa)
GOT2Aspartate aminotransferase. (430 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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