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ATP5F1C ATP5F1C CCT5 CCT5 NDUFB10 NDUFB10 EEF1A2 EEF1A2 YWHAB YWHAB NDUFA5 NDUFA5 HNRNPK HNRNPK ATP5F1A ATP5F1A COX2 COX2 AIFM1 AIFM1 NDUFA13 NDUFA13 SYNJ1 SYNJ1 GDAP1 GDAP1 SLC25A12 SLC25A12 SFXN3 SFXN3 NDUFS7 NDUFS7 AAK1 AAK1 EEF1A1 EEF1A1 INS INS EEF1D EEF1D PDHB PDHB RBM8A RBM8A ATP5PB ATP5PB YWHAQ YWHAQ VDAC2 VDAC2 LMNB2 LMNB2 LMNB1 LMNB1 SLC25A22 SLC25A22 NDUFB4 NDUFB4 ATXN3 ATXN3 NDUFA10 NDUFA10 SLC25A4 SLC25A4 ATP5PD ATP5PD VPS35 VPS35 AP2A1 AP2A1 NDUFS4 NDUFS4 CAMK2A CAMK2A HADHB HADHB NDUFA8 NDUFA8 ACLY ACLY CAMK2B CAMK2B COX6B1 COX6B1 HSP90AA1 HSP90AA1 HNRNPD HNRNPD RPS2 RPS2 RPL19 RPL19 ATP5MF ATP5MF GAD2 GAD2 VDAC3 VDAC3 CSNK2A2 CSNK2A2 SLC25A11 SLC25A11 RPS5 RPS5 CALB2 CALB2 LETM1 LETM1 EIF4G3 EIF4G3 NDUFA12 NDUFA12
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ATP5F1CATP synthase subunit gamma. (298 aa)
CCT5Chaperonin containing TCP1 subunit 5. (541 aa)
NDUFB10NADH:ubiquinone oxidoreductase subunit B10. (176 aa)
EEF1A2Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (463 aa)
YWHABTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta; Belongs to the 14-3-3 family. (246 aa)
NDUFA5NADH:ubiquinone oxidoreductase subunit A5. (108 aa)
HNRNPKUncharacterized protein. (454 aa)
ATP5F1AATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (560 aa)
COX2Cytochrome c oxidase subunit 2; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...] (227 aa)
AIFM1Apoptosis inducing factor mitochondria associated 1. (613 aa)
NDUFA13NADH:ubiquinone oxidoreductase subunit A13. (144 aa)
SYNJ1Synaptojanin 1. (1537 aa)
GDAP1Ganglioside induced differentiation associated protein 1; Belongs to the GST superfamily. (358 aa)
SLC25A12Solute carrier family 25 member 12; Belongs to the mitochondrial carrier (TC 2.A.29) family. (675 aa)
SFXN3Sidoreflexin. (321 aa)
NDUFS7NADH:ubiquinone oxidoreductase core subunit S7; Belongs to the complex I 20 kDa subunit family. (238 aa)
AAK1AP2 associated kinase 1. (969 aa)
EEF1A1Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (462 aa)
INSInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (105 aa)
EEF1DUncharacterized protein; Belongs to the EF-1-beta/EF-1-delta family. (280 aa)
PDHBPyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (359 aa)
RBM8ARNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. (174 aa)
ATP5PBATP synthase peripheral stalk-membrane subunit b. (256 aa)
YWHAQ14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (245 aa)
VDAC2Voltage dependent anion channel 2. (294 aa)
LMNB2Lamin B2; Belongs to the intermediate filament family. (641 aa)
LMNB1Lamin B1; Belongs to the intermediate filament family. (586 aa)
SLC25A22Solute carrier family 25 member 22; Belongs to the mitochondrial carrier (TC 2.A.29) family. (322 aa)
NDUFB4NADH:ubiquinone oxidoreductase subunit B4. (129 aa)
ATXN3Josephin domain-containing protein. (360 aa)
NDUFA10NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (355 aa)
SLC25A4Solute carrier family 25 member 4; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa)
ATP5PDATP synthase subunit d, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the cent [...] (162 aa)
VPS35Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. (796 aa)
AP2A1AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (985 aa)
NDUFS4NADH:ubiquinone oxidoreductase subunit S4. (175 aa)
CAMK2ACalcium/calmodulin dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (489 aa)
HADHBHydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta; Belongs to the thiolase-like superfamily. Thiolase family. (475 aa)
NDUFA8NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (175 aa)
ACLYATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. (1101 aa)
CAMK2BCalcium/calmodulin dependent protein kinase II beta. (542 aa)
COX6B1Cytochrome c oxidase subunit 6B1. (99 aa)
HSP90AA1Heat shock protein 90 alpha family class A member 1. (733 aa)
HNRNPDHeterogeneous nuclear ribonucleoprotein D. (355 aa)
RPS2S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family. (293 aa)
RPL19Ribosomal protein L19; Belongs to the eukaryotic ribosomal protein eL19 family. (198 aa)
ATP5MFUncharacterized protein. (104 aa)
GAD2Glutamate decarboxylase 2. (585 aa)
VDAC3Uncharacterized protein. (283 aa)
CSNK2A2Casein kinase 2 alpha 2; Belongs to the protein kinase superfamily. (350 aa)
SLC25A11Solute carrier family 25 member 11; Belongs to the mitochondrial carrier (TC 2.A.29) family. (315 aa)
RPS5Ribosomal protein S5; Belongs to the universal ribosomal protein uS7 family. (204 aa)
CALB2Calbindin 2. (271 aa)
LETM1Leucine zipper and EF-hand containing transmembrane protein 1. (732 aa)
EIF4G3Eukaryotic translation initiation factor 4 gamma 3. (1584 aa)
NDUFA12NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (145 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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