10 items (Capra hircus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	BGN	Biglycan; May be involved in collagen fiber assembly. Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily. (373 aa)
	POSTN	Periostin. (836 aa)
	CD4	CD4 molecule. (455 aa)
	COL5A2	Collagen type V alpha 2 chain. (1252 aa)
	CXCL13	C-X-C motif chemokine. (109 aa)
	COL1A1	Collagen type I alpha 1 chain. (1463 aa)
	FBN1	Fibrillin 1. (2860 aa)
	LOC102182683	C-X-C motif chemokine. (109 aa)
	IL1B	Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (266 aa)
	COL1A2	Collagen type I alpha 2 chain. (1128 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BGN	COL1A1	ENSCHIP00000003173	ENSCHIP00000023918	Biglycan; May be involved in collagen fiber assembly. Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.	Collagen type I alpha 1 chain.	0.910
BGN	COL1A2	ENSCHIP00000003173	ENSCHIP00000031191	Biglycan; May be involved in collagen fiber assembly. Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.	Collagen type I alpha 2 chain.	0.824
BGN	COL5A2	ENSCHIP00000003173	ENSCHIP00000009695	Biglycan; May be involved in collagen fiber assembly. Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.	Collagen type V alpha 2 chain.	0.868
BGN	FBN1	ENSCHIP00000003173	ENSCHIP00000023927	Biglycan; May be involved in collagen fiber assembly. Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.	Fibrillin 1.	0.721
BGN	IL1B	ENSCHIP00000003173	ENSCHIP00000029274	Biglycan; May be involved in collagen fiber assembly. Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.	Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family.	0.431
BGN	POSTN	ENSCHIP00000003173	ENSCHIP00000004170	Biglycan; May be involved in collagen fiber assembly. Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.	Periostin.	0.728
CD4	COL1A1	ENSCHIP00000006662	ENSCHIP00000023918	CD4 molecule.	Collagen type I alpha 1 chain.	0.454
CD4	CXCL13	ENSCHIP00000006662	ENSCHIP00000016774	CD4 molecule.	C-X-C motif chemokine.	0.913
CD4	IL1B	ENSCHIP00000006662	ENSCHIP00000029274	CD4 molecule.	Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family.	0.970
CD4	LOC102182683	ENSCHIP00000006662	ENSCHIP00000028640	CD4 molecule.	C-X-C motif chemokine.	0.834
COL1A1	BGN	ENSCHIP00000023918	ENSCHIP00000003173	Collagen type I alpha 1 chain.	Biglycan; May be involved in collagen fiber assembly. Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.	0.910
COL1A1	CD4	ENSCHIP00000023918	ENSCHIP00000006662	Collagen type I alpha 1 chain.	CD4 molecule.	0.454
COL1A1	COL1A2	ENSCHIP00000023918	ENSCHIP00000031191	Collagen type I alpha 1 chain.	Collagen type I alpha 2 chain.	0.999
COL1A1	COL5A2	ENSCHIP00000023918	ENSCHIP00000009695	Collagen type I alpha 1 chain.	Collagen type V alpha 2 chain.	0.962
COL1A1	FBN1	ENSCHIP00000023918	ENSCHIP00000023927	Collagen type I alpha 1 chain.	Fibrillin 1.	0.867
COL1A1	IL1B	ENSCHIP00000023918	ENSCHIP00000029274	Collagen type I alpha 1 chain.	Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family.	0.677
COL1A1	POSTN	ENSCHIP00000023918	ENSCHIP00000004170	Collagen type I alpha 1 chain.	Periostin.	0.834
COL1A2	BGN	ENSCHIP00000031191	ENSCHIP00000003173	Collagen type I alpha 2 chain.	Biglycan; May be involved in collagen fiber assembly. Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.	0.824
COL1A2	COL1A1	ENSCHIP00000031191	ENSCHIP00000023918	Collagen type I alpha 2 chain.	Collagen type I alpha 1 chain.	0.999
COL1A2	COL5A2	ENSCHIP00000031191	ENSCHIP00000009695	Collagen type I alpha 2 chain.	Collagen type V alpha 2 chain.	0.970