33 items (Capra hircus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PSMD1	26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa)
	ATF5	Activating transcription factor 5. (287 aa)
	SDHA	Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (665 aa)
	PSMA1	Proteasome subunit alpha type. (263 aa)
	NDUFA11	Uncharacterized protein. (141 aa)
	PSMB9	Proteasome subunit beta 9. (216 aa)
	GAPDH	Glyceraldehyde-3-phosphate dehydrogenase. (333 aa)
	COX6B1	Cytochrome c oxidase subunit 6B1. (99 aa)
	PSMB6	Proteasome subunit beta. (239 aa)
	PSMB10	Proteasome subunit beta. (273 aa)
	COX8A	Cytochrome c oxidase subunit 8A. (69 aa)
	TUBA1C	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa)
	EEF1B2	Uncharacterized protein; Belongs to the EF-1-beta/EF-1-delta family. (225 aa)
	NDUFA13	NADH:ubiquinone oxidoreductase subunit A13. (144 aa)
	TOMM20	Translocase of outer mitochondrial membrane 20. (145 aa)
	PRDX2	Thioredoxin domain-containing protein. (198 aa)
	PSMA5	Proteasome subunit alpha type. (241 aa)
	PSMD10	Proteasome 26S subunit, non-ATPase 10. (226 aa)
	PRDX1	Thioredoxin domain-containing protein. (206 aa)
	EEF1A1	Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (462 aa)
	NCK2	Cytoplasmic protein. (376 aa)
	PSMB5	Proteasome subunit beta. (263 aa)
	NCK1	Cytoplasmic protein. (377 aa)
	PSMB8	Proteasome subunit beta. (276 aa)
	ACTB	Uncharacterized protein. (375 aa)
	NDUFS1	NADH:ubiquinone oxidoreductase core subunit S1; Belongs to the complex I 75 kDa subunit family. (727 aa)
	UQCRC1	Ubiquinol-cytochrome c reductase core protein 1. (480 aa)
	AMPD1	AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (731 aa)
	PSMB7	Proteasome subunit beta. (277 aa)
	PXDN	Peroxidasin. (1525 aa)
	IFNG	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity); Belongs to the type II (or gamma) interferon family. (166 aa)
	EEF1A2	Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (463 aa)
	COX5B	Cytochrome c oxidase subunit 5B. (143 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTB	EEF1A1	ENSCHIP00000011080	ENSCHIP00000006227	Uncharacterized protein.	Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.	0.749
ACTB	EEF1A2	ENSCHIP00000011080	ENSCHIP00000016275	Uncharacterized protein.	Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.	0.647
ACTB	GAPDH	ENSCHIP00000011080	ENSCHIP00000025974	Uncharacterized protein.	Glyceraldehyde-3-phosphate dehydrogenase.	0.979
ACTB	IFNG	ENSCHIP00000011080	ENSCHIP00000016152	Uncharacterized protein.	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity); Belongs to the type II (or gamma) interferon family.	0.875
ACTB	NCK1	ENSCHIP00000011080	ENSCHIP00000009805	Uncharacterized protein.	Cytoplasmic protein.	0.880
ACTB	NCK2	ENSCHIP00000011080	ENSCHIP00000006571	Uncharacterized protein.	Cytoplasmic protein.	0.856
ACTB	PRDX1	ENSCHIP00000011080	ENSCHIP00000005982	Uncharacterized protein.	Thioredoxin domain-containing protein.	0.635
ACTB	PRDX2	ENSCHIP00000011080	ENSCHIP00000004684	Uncharacterized protein.	Thioredoxin domain-containing protein.	0.482
ACTB	PXDN	ENSCHIP00000011080	ENSCHIP00000015493	Uncharacterized protein.	Peroxidasin.	0.962
ACTB	SDHA	ENSCHIP00000011080	ENSCHIP00000018522	Uncharacterized protein.	Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).	0.726
ACTB	TOMM20	ENSCHIP00000011080	ENSCHIP00000003567	Uncharacterized protein.	Translocase of outer mitochondrial membrane 20.	0.612
ACTB	TUBA1C	ENSCHIP00000011080	ENSCHIP00000030319	Uncharacterized protein.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.743
COX5B	COX6B1	ENSCHIP00000016320	ENSCHIP00000026983	Cytochrome c oxidase subunit 5B.	Cytochrome c oxidase subunit 6B1.	0.999
COX5B	COX8A	ENSCHIP00000016320	ENSCHIP00000028754	Cytochrome c oxidase subunit 5B.	Cytochrome c oxidase subunit 8A.	0.998
COX5B	NDUFA11	ENSCHIP00000016320	ENSCHIP00000023746	Cytochrome c oxidase subunit 5B.	Uncharacterized protein.	0.997
COX5B	NDUFA13	ENSCHIP00000016320	ENSCHIP00000002346	Cytochrome c oxidase subunit 5B.	NADH:ubiquinone oxidoreductase subunit A13.	0.992
COX5B	NDUFS1	ENSCHIP00000016320	ENSCHIP00000013628	Cytochrome c oxidase subunit 5B.	NADH:ubiquinone oxidoreductase core subunit S1; Belongs to the complex I 75 kDa subunit family.	0.992
COX5B	SDHA	ENSCHIP00000016320	ENSCHIP00000018522	Cytochrome c oxidase subunit 5B.	Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).	0.892
COX5B	UQCRC1	ENSCHIP00000016320	ENSCHIP00000013966	Cytochrome c oxidase subunit 5B.	Ubiquinol-cytochrome c reductase core protein 1.	0.999
COX6B1	COX5B	ENSCHIP00000026983	ENSCHIP00000016320	Cytochrome c oxidase subunit 6B1.	Cytochrome c oxidase subunit 5B.	0.999